Effects of Mechanical Compression of a Fibrous Tissue Interface on Bone with or without High-Density Polyethylene Particles in a Rabbit Model of Prosthetic Loosening

2005 ◽  
Vol 87 (7) ◽  
pp. 1522 ◽  
Author(s):  
F.H.R. De Man
Keyword(s):  
High Density Polyethylene ◽  
Fibrous Tissue ◽  
Rabbit Model ◽  
High Density ◽  
Mechanical Compression ◽  
Prosthetic Loosening ◽  
Polyethylene Particles ◽  
Tissue Interface

The effects of the concentration of high-density polyethylene particles on the bone-implant interface

2000 ◽  
Vol 82-B (4) ◽  
pp. 595-600 ◽  
Author(s):  
R. A. Brooks ◽  
J. R. Sharpe ◽  
J. A. Wimhurst ◽  
B. J. Myer ◽  
E. N. Dawes ◽  
...  
Keyword(s):  
High Density Polyethylene ◽  
High Density ◽  
Bone Implant ◽  
Polyethylene Particles

Emulsion Crystallization of Submicron Sized High Density Polyethylene Particles Using Micromixer

2014 ◽  
Vol 47 (2) ◽  
pp. 141-145
Author(s):  
Sang Hoon Park ◽  
Seo Young Kim ◽  
Kwang Ho Song ◽  
Jaehoon Choe
Keyword(s):  
High Density Polyethylene ◽  
High Density ◽  
Polyethylene Particles

Composition and Surface Topography Effects on Apatite-Forming Ability of Ceramic-Polymer Composites

2003 ◽  
Vol 774 ◽  
Author(s):  
Susan M. Rea ◽  
Serena M. Best ◽  
William Bonfield
Keyword(s):  
Surface Topography ◽  
High Density Polyethylene ◽  
High Density ◽  
Apatite Layer ◽  
Biologically Active ◽  
Human Blood Plasma ◽  
Apatite Formation ◽  
Polyethylene Matrix ◽  
Composite Surface ◽  
X Ray

AbstractHAPEXTM (40 vol% hydroxyapatite in a high-density polyethylene matrix) and AWPEX (40 vol% apatite-wollastonite glass ceramic in a high density polyethylene matrix) are composites designed to provide bioactivity and to match the mechanical properties of human cortical bone. HAPEXTM has had clinical success in middle ear and orbital implants, and there is great potential for further orthopaedic applications of these materials. However, more detailed in vitro investigations must be performed to better understand the biological interactions of the composites and so the bioactivity of each material was assessed in this study. Specifically, the effects of controlled surface topography and ceramic filler composition on apatite layer formation in acellular simulated body fluid (SBF) with ion concentration similar to those of human blood plasma were examined. Samples were prepared as 1 cm × 1 cm × 1 mm tiles with polished, roughened, or parallel-grooved surface finishes, and were incubated in 20 ml of SBF at 36.5 °C for 1, 3, 7, or 14 days. The formation of a biologically active apatite layer on the composite surface after immersion was demonstrated by thin-film x-ray diffraction (TF-XRD), environmental scanning electron microscopy (ESEM) imaging and energy dispersive x-ray (EDX) analysis. Variations in sample weight and solution pH over the period of incubation were also recorded. Significant differences were found between the two materials tested, with greater bioactivity in AWPEX than HAPEXTM overall. Results also indicate that within each material the surface topography is highly important, with rougher samples correlated to earlier apatite formation.

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