scholarly journals Application of an Intraoperative Neuromonitoring System Using a Surface Pressure Sensor in Parotid Surgery: A Rabbit Model Study

2020 ◽  
Author(s):  
Eui-Suk Sung ◽  
Hyun-Keun Kwon ◽  
Sung-Chan Shin ◽  
Young-Il Cheon ◽  
Jung-Woo Lee ◽  
...  
Keyword(s):  
Surface Pressure ◽  
Pressure Sensor ◽  
Rabbit Model ◽  
Intraoperative Neuromonitoring ◽  
Model Study ◽  
Parotid Surgery

scholarly journals Application of Novel Intraoperative Neuromonitoring System Using an Endotracheal Tube With Pressure Sensor During Thyroid Surgery: A Porcine Model Study

2020 ◽  
Vol 13 (3) ◽  
pp. 291-298
Author(s):  
Eui-Suk Sung ◽  
Sung-Chan Shin ◽  
Hyun-Keun Kwon ◽  
Jia Kim ◽  
Da-Hee Park ◽  
...  
Keyword(s):  
Endotracheal Tube ◽  
Pressure Sensor ◽  
Pressure Sensors ◽  
Intraoperative Neuromonitoring ◽  
Injury Prediction ◽  
Laryngeal Muscle ◽  
Emg Amplitude ◽  
Muscle Twitching ◽  
Traction Injury ◽  
Model Study

Objectives. The loss of signal during intraoperative neuromonitoring (IONM) using electromyography (EMG) in thyroidectomy is one of the biggest problems. We have developed a novel IONM system with an endotracheal tube (ETT) with an attached pressure sensor instead of EMG to detect laryngeal twitching. The aim of the present study was to investigate the feasibility and reliability of this novel IONM system using an ETT with pressure sensor during thyroidectomy in a porcine model.Methods. We developed an ETT-attached pressure sensor that uses the piezoelectric effect to measure laryngeal muscle twitching. Stimulus thresholds, amplitude, and latency of laryngeal twitching evaluated using the pressure sensor were compared to those measured using transcartilage needle EMG. The measured amplitude changes by EMG and the pressure sensor during recurrent laryngeal nerve (RLN) traction injury were compared.Results. No significant differences in stimulus threshold intensity between EMG and the pressure sensor were observed. The EMG amplitude detected at 0.3 mA, increased with increasing stimulus intensity. When the stimulus was more than 1.0 mA, the amplitude showed a plateau. In a RLN traction injury experiment, the EMG amplitude did not recover even 20 minutes after stopping RLN traction. However, the pressure sensor showed a mostly recovery.Conclusion. The change in amplitude due to stimulation of the pressure sensor showed a pattern similar to EMG. Pressure sensors can be feasibly and reliably used for RLN traction injury prediction, RLN identification, and preservation through the detection of laryngeal muscle twitching. Our novel IONM system that uses an ETT with an attached pressure sensor to measure the change of surface pressure can be an alternative to EMG in the future.

A polymeric mini-stent designed to facilitate the vasectomy reversal operation. A rabbit model study

Biomaterials ◽  
2004 ◽  
Vol 25 (4) ◽  
pp. 729-734 ◽  
Author(s):  
Eric J. Vrijhof ◽  
Adriaan de Bruı̈ne ◽  
August A.B. Lycklama à Nijeholt ◽  
Leo H. Koole
Keyword(s):  
Rabbit Model ◽  
Model Study ◽  
Vasectomy Reversal

scholarly journals Detection of Pulmonary Embolism with Gallium-68 Macroaggregated Albumin Perfusion PET/CT: An Experimental Study in Rabbits

2020 ◽  
Author(s):  
Aziz Gültekin ◽  
Mustafa Çağdaş Çayır ◽  
Ayşe Uğur ◽  
Ferda Bir ◽  
Doğangün Yüksel
Keyword(s):  
Ct Perfusion ◽  
Rabbit Model ◽  
Histopathological Analysis ◽  
Model Study ◽  
Ventilation Imaging ◽  
Pet Ct ◽  
Medicine Physician ◽  
Animal Model Study ◽  
Gallium 68 ◽  
Sensitivity Specificity

Abstract This study was designed to evaluate the accuracy of to detect pulmonary emboli (PE) the Technegas SPECT/CT combined with 68Ga PET/CT in a rabbit model. One hour after artificial PE (n=6) and sham (n=6) models were created, Technegas SPECT/CT ventilation and 68Ga-MAA PET/CT perfusion scan (V/Q scan) were performed. All cases were performed ventilation imaging first. Technegas SPECT/CT and 68Ga-MAA PET/CT images were evaluated by a nuclear medicine physician who recorded the presence, number, and location of PE on a per-lobe basis. The sensitivity, specificity, and accuracy of Technegas SPECT/CT and 68Ga-MAA PET/CT for detecting PE were calculated using a histopathological evaluation as a reference standard.A total of 60 lung lobes were evaluated in 12 rabbits, and PE was detected in 20 lobes in V/Q scans and histopathological analysis. The overall sensitivity, specificity and accuracy were 100%, 100%, and 100%, respectively, for both the Technegas SPECT/CT and 68Ga-MAA PET/CT V/Q scans. Technegas/68Ga-MAA V/Q scans have good sensitivity, specificity and accuracy in the detection of PE in this animal model study.

scholarly journals Detection of Pulmonary Embolism with Gallium-68 Macroaggregated Albumin Perfusion PET/CT: An Experimental Study in Rabbits

2020 ◽  
Author(s):  
Aziz Gültekin ◽  
Mustafa Çağdaş Çayır ◽  
Ayşe Uğur ◽  
Ferda Bir ◽  
Doğangün Yüksel
Keyword(s):  
Ct Perfusion ◽  
Rabbit Model ◽  
Histopathological Analysis ◽  
Model Study ◽  
Ventilation Imaging ◽  
Pet Ct ◽  
Medicine Physician ◽  
Animal Model Study ◽  
Gallium 68 ◽  
Sensitivity Specificity

Abstract This study was designed to evaluate the accuracy of to detect pulmonary emboli (PE) the Technegas SPECT/CT combined with 68Ga PET/CT in a rabbit model. One hour after artificial PE (n=6) and sham (n=6) models were created, Technegas SPECT/CT ventilation and 68Ga-MAA PET/CT perfusion scan (V/Q scan) were performed. All cases were performed ventilation imaging first. Technegas SPECT/CT and 68Ga-MAA PET/CT images were evaluated by a nuclear medicine physician who recorded the presence, number, and location of PE on a per-lobe basis. The sensitivity, specificity, and accuracy of Technegas SPECT/CT and 68Ga-MAA PET/CT for detecting PE were calculated using a histopathological evaluation as a reference standard.A total of 60 lung lobes were evaluated in 12 rabbits, and PE was detected in 20 lobes in V/Q scans and histopathological analysis. The overall sensitivity, specificity and accuracy were 100%, 100%, and 100%, respectively, for both the Technegas SPECT/CT and 68Ga-MAA PET/CT V/Q scans. Technegas/68Ga-MAA V/Q scans have good sensitivity, specificity and accuracy in the detection of PE in this animal model study.

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