scholarly journals An isolated childhood myeloid sarcoma with germline MSH6 mutation—a case report

2021 ◽  
Vol 10 (8) ◽  
pp. 2136-2143
Author(s):  
Yu Liu ◽  
GuLiBaHa MaiMaiTi ◽  
Ying-Bin Yue ◽  
Ming-Wei Li ◽  
Shan-Bo Cao ◽  
...  
Keyword(s):  
Case Report ◽  
Myeloid Sarcoma ◽  
Msh6 Mutation

scholarly journals Isolated Gastric Myeloid Sarcoma: A Case Report and Review of the Literature

2014 ◽  
Vol 2014 ◽  
pp. 1-4 ◽  
Author(s):  
Pankit Vachhani ◽  
Prithviraj Bose
Keyword(s):  
Bone Marrow ◽  
Acute Myeloid Leukemia ◽  
Case Report ◽  
Myeloid Leukemia ◽  
Bone Marrow Involvement ◽  
Myeloid Sarcoma ◽  
Review Of The Literature ◽  
Aged Woman ◽  
Middle Aged Woman ◽  
Acute Myeloid

Myeloid sarcoma represents the proliferation of myeloblasts of acute myeloid leukemia (AML) at extramedullary sites. While extramedullary involvement in AML is uncommon in itself, isolated myeloid sarcomas, that is, myeloid sarcomas without any bone marrow involvement, are extremely rare and pose a diagnostic and therapeutic challenge. Here, we present the case of a middle-aged woman with isolated myeloid sarcoma in the stomach—an organ seldom involved by this disease. Additionally, the literature on the epidemiology, diagnosis, pathology, prognosis, and therapeutic options in myeloid sarcomas has been reviewed.

scholarly journals Nonleukemic myeloid sarcoma of the liver: a case report and review of literature

2011 ◽  
Vol 5 (2) ◽  
pp. 747-750 ◽  
Author(s):  
Xiao-Feng Hang ◽  
Hai-Guang Xin ◽  
Lei Wang ◽  
Wen-sheng Xu ◽  
Jun-xue Wang ◽  
...  
Keyword(s):  
Case Report ◽  
Myeloid Sarcoma ◽  
Review Of Literature

Blinatumomab resistant clone presenting as mixed phenotype myeloid sarcoma causing cord compression

2021 ◽  
Vol 156 (Supplement_1) ◽  
pp. S99-S100
Author(s):  
D S Dabrowski ◽  
E Wei
Keyword(s):  
African American ◽  
Case Report ◽  
Complete Remission ◽  
B Cell ◽  
African American Male ◽  
Lymphoblastic Leukemia ◽  
Cord Compression ◽  
Myeloid Sarcoma ◽  
Cell Precursor ◽  
Lower Extremity Weakness

Abstract Introduction/Objective Blinatumomab is a monoclonal antibody directed against CD19/CD3 utilized for the treatment of relapsed or refractory B-cell precursor acute lymphoblastic leukemia (ALL) and for the treatment of B-cell precursor ALL in first or second complete remission with minimal residual disease (MRD) ≥0.1%. Although Blinatumomab treatment has shown better overall survival, progression-free survival, and complete remission when compared to chemotherapy, most patients have a relapse and ultimately succumb to the disease. Interestingly, there are a number of cases reporting relapse in extramedullary places. The mechanisms for relapse in these unusual extramedullary sites are not well-understood. We herein report a case of a 20-year-old African American male with primary refractory Philadelphia-negative (Ph-) precursor B cell ALL with MLL rearrangement, who received treatment with Blinatumomab after achieving morphological remission with a pediatric-inspired regimen but found to be MRD +. Methods/Case Report A 20 year old African American male was found to have B cell precursor ALL. It was found to be Ph-. While initally receiving vincristine, prednisone, and aspariginase, the ALL proved to be refractory to treatment. Blinatumomab was used as second line therapy after the first failed remission. The patient remained with morphological response; however, remained MRD+ after three cycles of Blinatumomab. During the fourth cycle, the patient presented with back pain and lower extremity weakness. A spine MRI revealed an extradural mass in the thoracic spine causing cord compression. A thoracic laminectomy with partial removal of the mass, followed by radiation, was performed with improvement of symptoms. Pathology results of the extradural mass revealed a myeloid sarcoma with MLL rearrangement. Results (if a Case Study enter NA) NA Conclusion This case report demonstrates how patients treated with blinatumomab can have relapse in unusual extramedullary places. The possibility of leukemia manifesting in extramedullary sites should always be kept in mind by clinicians treating patients with Blinatumomab. The mechanisms of resistance against Blinatumomab are not well- understood and need further elucidation.

scholarly journals Isolated myeloid sarcoma of lumbar spine without bone marrow involvement: a rare case report and treatment dilemma

2021 ◽  
Vol 0 ◽  
pp. 0-0
Author(s):  
Janpreet S. Bhandohal ◽  
Leila Moosavi ◽  
Igor Garcia-Pacheco ◽  
Gian Yakoub ◽  
Rahul D. Polineni ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Case Report ◽  
Lumbar Spine ◽  
Rare Case ◽  
Bone Marrow Involvement ◽  
Myeloid Sarcoma ◽  
Rare Case Report

scholarly journals Gynecological Myeloid Sarcoma: Literature Review and a Case Report

2021 ◽  
Vol 14 (1) ◽  
pp. 31-44
Author(s):  
Aleksina Alekseevna Shatilova ◽  
L.L. Girshova ◽  
D.V. Zaitsev ◽  
I.G. Budaeva ◽  
Yu.V. Mirolyubova ◽  
...  
Keyword(s):  
Case Report ◽  
Literature Review ◽  
Myeloid Sarcoma

Case Report of Myeloid Sarcoma Masquerading as In-Transit Metastasis at a Previous Melanoma Site

2018 ◽  
Vol 40 (11) ◽  
pp. 831-835
Author(s):  
Jonathan L. Curry ◽  
Michael T. Tetzlaff ◽  
Sa A. Wang ◽  
Gene Landon ◽  
Nail Alouch ◽  
...  
Keyword(s):  
Case Report ◽  
Myeloid Sarcoma ◽  
In Transit

scholarly journals Myeloid sarcoma of the tongue as a first manifestation of acute promyelocytic leukemia: A case report

2020 ◽  
Vol 25 (2) ◽  
pp. 174-177
Author(s):  
Felipe L. Ignacio-Cconchoy ◽  
Vicente A. Benites-Zapata ◽  
Rommel L. Yanac-Avila ◽  
César T. Vela-Velàsquez
Keyword(s):  
Case Report ◽  
Acute Promyelocytic Leukemia ◽  
Promyelocytic Leukemia ◽  
Myeloid Sarcoma

scholarly journals Extramedullary Monoblastic Sarcoma/Myeloid Sarcoma of Paraspinal Region Without Myeloid Leukemia: A Rare Case Report

2018 ◽  
Vol 150 (suppl_1) ◽  
pp. S49-S50
Author(s):  
Mitul Modi ◽  
Vipulkumar Prajapati ◽  
Irappa Madabhavi ◽  
Himanshu Kavani ◽  
Mansi Shah
Keyword(s):  
Case Report ◽  
Myeloid Leukemia ◽  
Rare Case ◽  
Myeloid Sarcoma ◽  
Rare Case Report
Sign in / Sign up

Export Citation Format

Share Document