scholarly journals Correlation study of cytokine levels in alveolar lavage fluid with exhaled nitric oxide and lung function in children with bronchial asthma

2021 ◽  
Vol 0 (0) ◽  
pp. 0-0
Author(s):  
Ying Lou ◽  
Qiuping Ke ◽  
Huailiang Cui ◽  
Ying Shang ◽  
Chengsheng Yang
Keyword(s):  
Nitric Oxide ◽  
Lung Function ◽  
Bronchial Asthma ◽  
Lavage Fluid ◽  
Correlation Study ◽  
Exhaled Nitric Oxide ◽  
Cytokine Levels

PS-172 Serum 25-hydroxyvitamin D In Relation To Lung Function And Exhaled Nitric Oxide In Children

2014 ◽  
Vol 99 (Suppl 2) ◽  
pp. A173.2-A173
Author(s):  
J Huang ◽  
TC Yao ◽  
W Yeh ◽  
S Lai ◽  
S Liao ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Lung Function ◽  
Exhaled Nitric Oxide ◽  
Hydroxyvitamin D ◽  
25 Hydroxyvitamin D

The Utility of Serum IL-1β and CRP Together with Fractional Exhaled Nitric Oxide in the Diagnosis of Asthma in Adults

2021 ◽  
Vol 19 (8) ◽  
pp. 119-124
Author(s):  
Hayder Abdul-Amir Makki Al-Hindy ◽  
Ali Jihad Hemid Al-Athari ◽  
Mazin J. Mousa ◽  
Safa Jihad Hameed ◽  
Suhad Hafidh Obeed
Keyword(s):  
Nitric Oxide ◽  
Sensitivity And Specificity ◽  
Bronchial Asthma ◽  
High Sensitivity ◽  
Exhaled Nitric Oxide ◽  
Fractional Exhaled Nitric Oxide ◽  
Asthmatic Patients ◽  
Significant Difference ◽  
Asthma Patients ◽  
Hs Crp

Background: Bronchial asthma (BrA), recognized lately as an umbrella, covers various subtypes rather than only one disease. Asthma is a chronic inflammation of the airways, in which cytokines could play a crucial role in its pathogenesis. Hence, labors to progress noninvasive markers for asthma had centered through this era. Presently, the fractional exhaled nitric oxide (FeNO), serum C-reactive protein (CRP), and interleukin levels are emerging analytical biomarkers in this field. FeNO is a noninvasive and practical tool even in mild asthma. This study aimed to evaluate the utility of serum IL-1β and CRP together with fractional exhaled nitric oxide in the diagnosis of adult bronchial asthma. Method: The study was a case control, including 150-patients and 100-healthy controls. FeNO tests, measurements of plasma levels IL-1β and HS-CRP had undertaken for all the participants. The statistical data had examined by SPSS (V/27) for Windows. Descriptive data of the variables had compatibly used. A significance lower than or identical to 0.05 had intended. ROC curve examination of FeNO tests, IL-1β, and HS-CRP, to predict asthma from healthy control had applied. Results: there was a significant difference in the FeNo test, HS-CRP levels, and BMI, while no significant difference in all other variables between the groups. The FeNo results correlate positively, though not significantly, with the levels of IL-1β in asthmatic patients (> 0.05). There was a nonsignificant negative correlation between the FeNo results with the level of HSCRP. The accuracy, sensitivity, and specificity of the IL-1β to distinguish asthma were 68.6% and 58% at 95% CI [0.41-0.745], respectively, which was not significant (p>0.05). However, ROC analysis of HS-CRP revealed predictability for asthma patients (p-0.000), with higher accuracy, sensitivity, and specificity: 89.9%, and 68.1% at 95% CI [0.820-0.979], respectively. The FeNo tests revealed highly significant (0.000), high sensitivity, and specific (91% for both) with high 95% CI [0.938-1.000] predictability for asthma. Conclusion: The utility of circulating HS-CRP is more valuable than IL-1β when combined with fractional exhaled nitric oxide in the diagnosis of asthma. Novel biomarkers could improve the precision of this field.

P205 CONCORDANCE OF CHANGES IN EXHALED NITRIC OXIDE, ACQ7, ASTHMA SYMPTOMS AND LUNG FUNCTION

2019 ◽  
Vol 123 (5) ◽  
pp. S33-S34
Author(s):  
P. Silkoff ◽  
R. Leard ◽  
M. Sarno ◽  
V. Balasubramanyam ◽  
B. Awabdy ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Lung Function ◽  
Exhaled Nitric Oxide ◽  
Asthma Symptoms

scholarly journals Relationship between Exhaled Nitric Oxide and Small Airway Lung Function in Normal and Asthmatic Children

2011 ◽  
Vol 60 (1) ◽  
pp. 53-59 ◽  
Author(s):  
Naoki Nakajima ◽  
Hiroyuki Mochizuki ◽  
Reiko Muramatsu ◽  
Satomi Hagiwara ◽  
Takahisa Mizuno ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Lung Function ◽  
Exhaled Nitric Oxide ◽  
Small Airway ◽  
Asthmatic Children

Fractional Exhaled Nitric Oxide (FENO), Lung Function and Airway Hyperresponsiveness in Naïve Atopic Asthmatic Children

2004 ◽  
Vol 41 (7) ◽  
pp. 759-765 ◽  
Author(s):  
Michele Miraglia del Giudice ◽  
F. P. Brunese ◽  
G. L. Piacentini ◽  
M. Pedullà ◽  
C. Capristo ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Lung Function ◽  
Airway Hyperresponsiveness ◽  
Exhaled Nitric Oxide ◽  
Fractional Exhaled Nitric Oxide ◽  
Asthmatic Children

scholarly journals Exhaled nitric oxide: a new lung function test.

Thorax ◽  
1996 ◽  
Vol 51 (3) ◽  
pp. 233-237 ◽  
Author(s):  
P J Barnes ◽  
S A Kharitonov
Keyword(s):  
Nitric Oxide ◽  
Lung Function ◽  
Lung Function Test ◽  
Exhaled Nitric Oxide ◽  
Function Test
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