scholarly journals Effects of sublingual-specific immunotherapy on pulmonary function and exhaled nitric oxide levels in asthmatic children with and without allergic rhinitis

2020 ◽  
Vol 9 (5) ◽  
pp. 686-694
Author(s):  
Tao Ai ◽  
Li Wang ◽  
Ronghua Luo ◽  
Yinghong Fan ◽  
Huiling Liao ◽  
...  
2017 ◽  
Vol 2017 ◽  
pp. 1-13 ◽  
Author(s):  
Hsin-Chia Lin ◽  
Hao-Pai Lin ◽  
Hsin-Hui Yu ◽  
Li-Chieh Wang ◽  
Jyh-Hong Lee ◽  
...  

Tai-Chi-Chuan (TCC) is an exercise of low-to-moderate intensity which is suitable for asthmatic patients. The aim of our study is to investigate improvements of the lung function, airway inflammation, and quality of life of asthmatic children after TCC. Participants included sixty-one elementary school students and they were divided into asthmatic (n=29) and nonasthmatic (n=32) groups by the International Study of Asthma and Allergies in Childhood (ISAAC) questionnaire. Among them, 20 asthmatic and 18 nonasthmatic children volunteered to participate in a 60-minute TCC exercise weekly for 12 weeks. Baseline and postintervention assessments included forced expiratory volume in one second (FEV1), forced vital capacity (FVC), peak expiratory flow rate (PEFR), fractional exhaled nitric oxide (FeNO) level, and Standardised Pediatric Asthma Quality of Life Questionnaire (PAQLQ(S)). After intervention, the level of FeNO decreased significantly; PEFR and the FEV1/FVC also improved significantly in both asthmatic group and nonasthmatic group after TCC. The asthmatic children also had improved quality of life after TCC. The results indicated that TCC could improve the pulmonary function and decrease airway inflammation in both children with mild asthma and those without asthma. It also improves quality of life in mild asthmatic children. Nevertheless, further studies are required to determine the effect of TCC on children with moderate-to-severe asthma.


Children ◽  
2020 ◽  
Vol 8 (1) ◽  
pp. 3
Author(s):  
Yoon Young Jang ◽  
Ji Young Ahn

Fractional exhaled nitric oxide (FeNO) is a non-invasive test for evaluating the degree of airway inflammation and for the diagnosis, evaluation, and treatment of asthma. We attempted to measure FeNO levels in Korean children with asthma and determine its cutoff value for diagnosing asthma. We enrolled 176 children and adolescents between the ages of 5 and 18 years, who visited for the evaluation of chronic cough, shortness of breath, and wheezing. Among them, 138 patients who underwent skin prick tests or inhalation Immuno CAP (UniCAP; Pharmacia, Uppsala, Sweden) tests for allergy testing together with a pulmonary function test were included. FeNO was measured using a NIOX MINO (Aerocrine AB, Solna, Sweden) instrument according to the American Thoracic Society/European Respiratory Society (ATS/ERS) guidelines. There were 29 patients with asthma, 43 with rhinitis, and 38 with asthma and allergic rhinitis. In the asthma group, FeNO levels significantly correlated with total immunoglobulin E (r = 0.572, p < 0.001), but did not show significant correlation with pulmonary function test parameters (forced vital capacity—FVC, forced expiratory volume in one second—FEV1, FEV1/FVC) or PC20 (provocative concentration of methacholine causing a 20% fall in FEV1). The FeNO cutoff values obtained in the asthma and asthma rhinitis groups were 16.5 ppb and 18.5 ppb, respectively. Hence, we provide a FeNO cutoff value according to the presence or absence of rhinitis in pediatric patients with asthma.


1997 ◽  
Vol 24 (5) ◽  
pp. 312-318 ◽  
Author(s):  
C. A. Byrnes ◽  
S. Dinarevic ◽  
E. A. Shinebourne ◽  
P. J. Barnes ◽  
A. Bush

Author(s):  
Ricardo J. Saranz ◽  
Natalia A. Lozano ◽  
Alejandro Lozano ◽  
Graciela Alegre ◽  
Paula Robredo ◽  
...  

2011 ◽  
Vol 60 (1) ◽  
pp. 53-59 ◽  
Author(s):  
Naoki Nakajima ◽  
Hiroyuki Mochizuki ◽  
Reiko Muramatsu ◽  
Satomi Hagiwara ◽  
Takahisa Mizuno ◽  
...  

2009 ◽  
Vol 102 (6) ◽  
pp. 469-474 ◽  
Author(s):  
Hiromi Tadaki ◽  
Hiroyuki Mochizuki ◽  
Reiko Muramastu ◽  
Satomi Hagiwara ◽  
Satoru Takami ◽  
...  

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