scholarly journals Mucinous adenocarcinoma of perianal region: an uncommon disease treated with neo-adjuvant chemo-radiation

2016 ◽  
Vol 1 ◽  
pp. 52-52 ◽  
Author(s):  
Abhishek Purkayastha ◽  
Neelam Sharma ◽  
Vibha Dutta ◽  
Niharika Bisht ◽  
Tejas Pandya
2020 ◽  
Vol 2020 ◽  
pp. 1-4
Author(s):  
Fahmi Pramaditto Azmi ◽  
Nur Afdzillah Abdul Rahman ◽  
Luqman Mazlan ◽  
Normala Basiron ◽  
Farrah-Hani Imran

Mucinous adenocarcinoma of the perianal region is an oncologic rarity posing a diagnostic and therapeutic dilemma for treating oncologists. This is due to the low number of reported cases, compounded by the lack of definitive therapeutic guidelines. It accounts for 2% to 3% of all gastrointestinal malignancies and is historically known to arise from chronic anal fistulas and ischiorectal or perianal abscesses. We hereby report an interesting case of perianal mucinous adenocarcinoma in a 66-year-old male initially treated for a horseshoe abscess with complex fistulae. He presented with a 6-month history of a discharging growth in perianal region and painful defecation associated with occasional blood mixed stools. An incisional biopsy from the ulcer revealed mucinous adenocarcinoma. Contrast-enhanced computed tomography (CT) scan and magnetic resonance imaging (MRI) scan showed a localized perianal growth which involves the internal and external sphincter as well as suspicious involvement in the posterior aspect of the levator ani/puborectalis sling, which was further confirmed with colonoscopy (see figures). With no preset treatment protocol for this rare entity, he was managed with an abdominoperineal resection (APR) and vertical rectus abdominis myocutaneous flap (VRAM) tissue reconstruction. He had a turbulent postoperative period including intestinal obstruction secondary to internal herniation of bowel resulting in flap failure. The subsequent perineal wound was managed conservatively with advanced wound care and has since completely healed.


2004 ◽  
Vol 51 (3) ◽  
pp. 325
Author(s):  
Chul Hi Park ◽  
Dal Mo Yang ◽  
Jee Eun Kim ◽  
Soo Jin Choi

2008 ◽  
Vol 59 (5) ◽  
pp. 329
Author(s):  
Dong Hyun Lee ◽  
Young Hwan Lee ◽  
Kyung Jae Jung ◽  
Young Chan Park ◽  
Ho Kyun Kim ◽  
...  

2018 ◽  
Author(s):  
Galang Daphne Gayle ◽  
Nerissa Ang-Golangco ◽  
Richard Cedeno Joseph Ray

2017 ◽  
Vol 4 (41) ◽  
pp. 38
Author(s):  
Irina Strâmbu ◽  
Livia Luculescu ◽  
Ciprian Bolca ◽  
Diana Leonte ◽  
Daniela Vasile ◽  
...  

Author(s):  
Mitchell W. Couldwell ◽  
Samuel Cheshier ◽  
Philipp Taussky ◽  
Vance Mortimer ◽  
William T. Couldwell

Moyamoya is an uncommon disease that presents with stenoocclusion of the major vasculature at the base of the brain and associated collateral vessel formation. Many pediatric patients with moyamoya present with transient ischemic attacks or complete occlusions. The authors report the case of a 9-year-old girl who presented with posterior fossa hemorrhage and was treated with an emergency suboccipital craniotomy for evacuation. After emergency surgery, an angiogram was performed, and the patient was diagnosed with moyamoya disease. Six months later, the patient was treated for moyamoya using direct and indirect revascularization; after surgery there was excellent vascularization in both regions of the bypass and no further progression of moyamoya changes. This case illustrates a rare example of intracerebral hemorrhage associated with moyamoya changes in the posterior vascularization in a pediatric patient and subsequent use of direct and indirect revascularization to reduce the risk of future hemorrhage and moyamoya progression.


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