AB002. Tracheal surgery

2018 ◽  
Vol 2 ◽  
pp. AB002-AB002
Author(s):  
Douglas J. Mathisen
Keyword(s):  
Tracheal Surgery

Interventional lung assist (ILA) during neck wound repair after tracheal surgery: case report

2006 ◽  
Vol 23 (Supplement 38) ◽  
pp. 25
Author(s):  
I. Rovira ◽  
G. Fita ◽  
A. Alcón ◽  
P. Matute ◽  
M. Iglesias ◽  
...  
Keyword(s):  
Case Report ◽  
Wound Repair ◽  
Tracheal Surgery ◽  
Neck Wound ◽  
Interventional Lung Assist

scholarly journals Tracheal surgery in children: outcome of a 12-year survey

2017 ◽  
Vol 26 (4) ◽  
pp. 660-666 ◽  
Author(s):  
Luigi Arcieri ◽  
Vitali Pak ◽  
Vincenzo Poli ◽  
Roberto Baggi ◽  
Paola Serio ◽  
...  
Keyword(s):  
Tracheal Surgery

scholarly journals MacchiariniGate: The Fall from Grace of Stem Cell Healer, Paolo Macchiarini, and Clues and Concerns from the Early Literature that Cast Ethical Doubts

2018 ◽  
Vol 9 (1) ◽  
pp. 1-12
Author(s):  
Jaime A. Teixeira Da Silva
Keyword(s):  
Lung Cancer ◽  
Stem Cells ◽  
Stem Cell ◽  
High Risk ◽  
Domino Effect ◽  
Nobel Committee ◽  
Tracheal Surgery ◽  
High Profile ◽  
Ethical Approval ◽  
Made In

After a long and successful career in tracheal surgery and lung cancer, Paolo Macchiarini became very famous in 2008 with the transplantation of a trachea from a cadaver that then apparently used the patient’s own stem cells to supposedly regenerate new trachea, i.e., tissue-engineered tracheae. Among the nine patients that received this revolutionary treatment, using biological or artificial tracheae, under Macchiarini’s supervision, six have reportedly died. Although several critics had expressed concerns with the procedures, allegations of misconduct against Macchiarini first arose in August of 2014 by four Karolinska Institutet (KI) colleagues, and an independent investigation was called for by KI based on claims made in seven published papers. Among the claims were the fact that the procedure constituted a high risk, information on the patients was incomplete and that there was no or incomplete ethical approval, thus constituting misconduct. His CV was also shown to contain inaccuracies. By September 10, 2016, most of these claims have now proved to be true, and Macchiarini was found guilty of misconduct by KI. This paper looks primarily at earlier published papers by Macchiarini and his collaborators in a search for clues to better understand the evolution of altruism, or narcissism. An assessment of the controversial papers, and of letters written by critics and skeptics like Pierre R. Delaere, indicate that insufficient experimental evidence was presented for several case studies, and that claims made about the success of the procedures exceeded what was shown by the evidence. A domino effect of personal and professional tragedies ensued, in rapid succession, between 2014 and 2016. The effect on the field of stem cell research has been chilling, and the side-effects have taken their toll, with several high-profile resignations, primarily at KI, within the Swedish education system and in the Nobel Committee. This case has mesmerized the bioethics and biomedical communities for years.   

scholarly journals P-212REDO TRACHEAL SURGERY FOLLOWING PREVIOUS RESECTION

2013 ◽  
Vol 17 (suppl_1) ◽  
pp. S55-S55
Author(s):  
Ciprian Bolca ◽  
M. Dumitrescu ◽  
O. Danaila ◽  
C. Paleru ◽  
I. Cordos
Keyword(s):  
Tracheal Surgery

scholarly journals Anaesthetic Management of Tracheal Surgery Using the Laryngeal Mask Airway

1994 ◽  
Vol 22 (1) ◽  
pp. 69-73 ◽  
Author(s):  
J. V. Divatia ◽  
R. Sareen ◽  
S. M. Upadhye ◽  
K. S. Sharma ◽  
J. R. Shelgaonkar
Keyword(s):  
Laryngeal Mask Airway ◽  
Anaesthetic Management ◽  
Laryngeal Mask ◽  
Tracheal Surgery

Long-term outcomes of surgery for pulmonary artery sling in children†

2019 ◽  
Vol 56 (2) ◽  
pp. 369-376 ◽  
Author(s):  
Matthew S Yong ◽  
Michael Z L Zhu ◽  
Douglas Bell ◽  
Nelson Alphonso ◽  
Johann Brink ◽  
...  
Keyword(s):  
Pulmonary Artery ◽  
Forced Vital Capacity ◽  
Vital Capacity ◽  
Heart Association ◽  
Forced Expiratory Volume ◽  
Functional Class ◽  
Long Term Outcomes ◽  
Tracheal Surgery

Abstract OBJECTIVES Pulmonary artery (PA) sling is a rare vascular anomaly often associated with congenital tracheal stenosis. We describe the long-term outcomes with repair of this condition. METHODS A retrospective study was conducted at 2 institutions. From 1984 to 2018, 33 patients with PA sling underwent repair. RESULTS The median age at the time of surgery was 5.9 months (quartile 1–3: 2.5–12 months). Concomitant tracheal surgery was required in 21 patients (64%) where slide tracheoplasty was used in 11 patients (52%). There were no early deaths in patients who did not require tracheal surgery (n = 12). Operative mortality was 22% (2 of 9 patients) between 1984 and 1993, 11% (1 of 9 patients) between 1994 and 2003 and 6.7% (1 of 15 patients) between 2004 and 2018. The 15-year probability of survival for patients who had PA sling repair alone was 100%, and for patients who required PA sling and tracheal repair was 76 ± 10% (95% confidence interval 51–89%) (P = 0.08). The mean follow-up for survivors was 14 ± 9.8 years (3 months–33 years). All survivors were in the New York Heart Association functional class I/II at the last follow-up. Spirometry performed at a median age of 10.4 years after PA sling and tracheal surgery demonstrated obstructive lung defects with median forced expiratory volume in 1 s of 1.0 l (48% predicted), forced vital capacity of 1.5 l (74% predicted) and forced expiratory volume in 1 s/forced vital capacity of 0.69 (78% predicted). CONCLUSIONS Early mortality after PA sling repair is determined by the need for tracheal surgery. Though late survival was excellent, and the majority of survivors remained asymptomatic, long-term respiratory assessment and follow-up is warranted for these patients.

Repair of pulmonary artery sling with tracheal and intracardiac defects

2020 ◽  
Vol 28 (8) ◽  
pp. 463-469
Author(s):  
Nagarajan Muthialu ◽  
Thomas Martens ◽  
Meletios Kanakis ◽  
Laurynas Bezuska ◽  
Masakazu Nakao ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cardiopulmonary Bypass ◽  
Pulmonary Artery ◽  
Surgical Repair ◽  
Univariate Analysis ◽  
Surrogate Marker ◽  
Interquartile Range ◽  
Pulmonary Artery Sling ◽  
Tracheal Surgery ◽  
Cardiopulmonary Bypass Time

Background Pulmonary artery sling is commonly associated with tracheal stenosis and intracardiac anomalies. While surgical repair is standardized, coexistent anomalies often determine outcomes. With the paucity of risk stratification, this study aimed to review our experience and stratify risk factors for the surgical outcome of complex pulmonary artery sling repair in the presence of airway or intracardiac lesions. Methods Seventy-nine consecutive children with pulmonary artery sling were evaluated retrospectively following surgical repair. Median age at surgery was 5 months (interquartile range 3–9). Surgical approaches included pulmonary artery sling alone ( n = 10), pulmonary artery sling with tracheoplasty ( n = 41), and pulmonary artery sling with both intracardiac and tracheal surgery ( n = 28). Results There were 7 early (8.8%) deaths. Two patients after left pulmonary artery reimplantation needed revision of the anastomosis. The median intensive care and hospital stay were 11 (interquartile range 9.2–24.8) and 17.9 (interquartile range 4.3–19.8) days, and considerably longer when associated tracheal surgery ( p = 0.002). Follow-up was complete in 66/69 and 3 (3.8%) children died late: 2.7, 10.2, and 17 months after surgery. Univariate analysis showed abnormal lung and coexisting structural heart disease as risk factors. Multivariate analysis revealed total cardiopulmonary bypass time as an independent predictor of overall mortality. Conclusion Complex pulmonary artery sling repair can be performed with a good surgical outcomes even when associated with airway malformations or structural heart diseases. Lung abnormality and longer cardiopulmonary bypass time as a surrogate marker of complex surgery, are possible risk factors.

Y-shaped catheter improves carbon dioxide clearance during apnoeic oxygenation in tracheal surgery

2019 ◽  
Vol 56 (2) ◽  
pp. 393-399
Author(s):  
Naoya Yokota ◽  
Tetsuhiko Go ◽  
Atsushi Fujiwara ◽  
Natsumi Matsuura ◽  
Hiroyasu Yokomise
Keyword(s):  
Carbon Dioxide ◽  
Partial Pressure ◽  
Pure Oxygen ◽  
Tracheal Resection ◽  
Tracheal Reconstruction ◽  
Tracheal Surgery ◽  
Co2 Partial Pressure ◽  
Catheter Group ◽  
Carbon Dioxide Co2 ◽  
Apnoeic Oxygenation

AbstractOBJECTIVESApnoeic oxygenation is a ventilation method in tracheal surgery, but has the disadvantage of causing progressive hypercapnia. The aim of this experimental study was to evaluate the efficacy of a Y-shaped catheter for the prevention of accumulation of carbon dioxide (CO2) in tracheal surgery.METHODSSurgery for tracheal resection and reconstruction was performed in 10 beagles under general anaesthesia. Before transecting the trachea, the dogs were hyperventilated for 10 min with pure oxygen. After the airway was opened, ventilation was maintained with a small catheter for apnoeic oxygenation for 30 min until the end of the tracheal reconstruction. Y-shaped catheters were used in 5 dogs and straight catheters were used in 5 dogs for oxygen insufflation. Haemodynamic values and blood gas values were evaluated and compared between the 2 groups.RESULTSThe mean elevation in the CO2 partial pressure value per minute from 5 min after the start of the procedure to the end of apnoeic oxygenation was 1.34 mmHg [95% confidence interval (CI) 1.00–1.68] in the Y-shaped catheter group and 2.03 mmHg (95% CI 1.54–2.53) in the straight catheter group (P < 0.018). The total CO2 partial pressure elevation value was 59.5 mmHg in the Y-shaped catheter group and 89.0 mmHg in the straight catheter group (P < 0.006). There were no significant differences in haemodynamic values between the 2 groups.CONCLUSIONSApnoeic oxygenation using a Y-shaped catheter represses the accumulation of CO2 compared with a straight catheter in canine tracheal resection–reconstruction surgery.

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