AB004. OA01.04: Predictors of occult pleural dissemination detected intraoperatively in patients with thymic tumors

Mediastinum ◽  
2018 ◽  
Vol 2 ◽  
pp. AB004-AB004
Author(s):  
Weigang Zhao ◽  
Yi Yang
2006 ◽  
Vol 56 (2) ◽  
pp. 101-104
Author(s):  
Masayuki Sugano ◽  
Yoshimi Otani ◽  
Osamu Kawashima ◽  
Mitsuhiro Kamiyoshihara ◽  
Kimihiro Shimizu ◽  
...  

Author(s):  
D. Okazaki ◽  
K. Tatekawa ◽  
K. Uchiyama ◽  
C. Hashizume ◽  
Y. Manabe ◽  
...  

2021 ◽  
Vol 16 (1) ◽  
Author(s):  
Zuodong Song ◽  
Shu Zhu ◽  
Tangbing Chen ◽  
Weigang Zhao

Abstract Background Thymic tumors usually present with adjacent organ invasion or pleural dissemination, but very few studies have reported on occult pleural dissemination detected intraoperatively. This study aimed to investigate the risk factors that can predict pleural dissemination preoperatively. Methods Consecutive patients with thymic tumors who underwent surgery from January 2010 to January 2017 were reviewed. Only patients without pleural dissemination detected preoperatively were included in this study. Demographic, clinical, pathological, and survival data were collected for statistical analysis. Further analyses were performed to find the risk factors of occult pleural dissemination. Results A total of 352 patients with thymic tumors were included in this study. Seven patients had pleural dissemination detected intraoperatively. All pleural dissemination cases were in clinical Masaoka-Koga stage III, and most underwent the video-assisted thoracoscopic surgery (VATS) approach (or VATS exploration). Univariate analysis showed that positive squamous cell carcinoma (SCC) antigen was the only predictor of pleural dissemination (p = 0.009). Tiny nodules close to the diaphragm were detected in the computed tomography scans of 1 case after reviewing the imaging data. Tumor recurrence occurred in 5 patients during follow-up. The disease-free survival rates were better in patients with a solitary nodule than those with multiple nodules (p = 0.019). No significant difference was detected in terms of disease-free survival rates between SCC antigen positive and SCC antigen negative patients. Conclusions Positive SCC antigen was the only detected risk factor for predicting pleural dissemination in thymic tumors preoperatively in this study. The VATS approach (including VATS exploration) is suggested for patients with clinical Masaoka-Koga stage III and SCC antigen positive thymic tumors, according to our experience.


1991 ◽  
Vol 27 (3) ◽  
pp. 343
Author(s):  
Ho Son Chung ◽  
Sang Jin Lee ◽  
Mi Soo Hwang ◽  
Kil Ho Cho ◽  
Jae Chun Chang ◽  
...  
Keyword(s):  

Cancers ◽  
2021 ◽  
Vol 13 (14) ◽  
pp. 3599
Author(s):  
Francesco Gentili ◽  
Ilaria Monteleone ◽  
Francesco Giuseppe Mazzei ◽  
Luca Luzzi ◽  
Davide Del Roscio ◽  
...  

Thymic tumors are rare neoplasms even if they are the most common primary neoplasm of the anterior mediastinum. In the era of advanced imaging modalities, such as functional MRI, dual-energy CT, perfusion CT and radiomics, it is possible to improve characterization of thymic epithelial tumors and other mediastinal tumors, assessment of tumor invasion into adjacent structures and detection of secondary lymph nodes and metastases. This review aims to illustrate the actual state of the art in diagnostic imaging of thymic lesions, describing imaging findings of thymoma and differential diagnosis.


1997 ◽  
Vol 4 (1) ◽  
pp. 46-56 ◽  
Author(s):  
Paul M. Schneider ◽  
Christian Fellbaum ◽  
Ulrich Fink ◽  
Elfriede Bollschweiler ◽  
Heinz W. Präuer

2009 ◽  
Vol 19 (1) ◽  
pp. 121-131 ◽  
Author(s):  
Enrico Ruffini ◽  
Pier Luigi Filosso ◽  
Alberto Oliaro
Keyword(s):  

1986 ◽  
Vol 23 (3) ◽  
pp. 270-277 ◽  
Author(s):  
C. F. Kuper ◽  
R. B. Beems ◽  
V. M. H. Hollanders

Spontaneous thymic lesions were investigated in Wistar (Cpb:WU) rats. Thymic tumors were not uncommon and most showed medullary differentiation. Thymic involution was investigated in a limited group of animals in which the survival rate for males and females was similar. The histological pattern of thymic involution differed between sexes. Severe thymic involution occurred more frequently in males than in females and at an earlier age.


CHEST Journal ◽  
1994 ◽  
Vol 105 (6) ◽  
pp. 1884-1885 ◽  
Author(s):  
Masahiko Higashiyama ◽  
Osamu Doi ◽  
Ken Kodama ◽  
Hideoki Yokouchi

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