AB060. 156. Post-operative pain following laparoscopic right hemicolectomy for Crohn’s disease: a comparative study

2018 ◽  
Vol 2 ◽  
pp. AB060-AB060
Author(s):  
Kevin McKevitt ◽  
Shaheel Sahebally ◽  
Sinead Galvin ◽  
John Patrick Burke
Keyword(s):  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Comparative Study ◽  
Right Hemicolectomy ◽  
Post Operative Pain ◽  
Laparoscopic Right Hemicolectomy

scholarly journals AB057. 33. Post-operative pain following laparoscopic right hemicolectomy for Crohn’s disease: a comparative study

2019 ◽  
Vol 3 ◽  
pp. AB057-AB057
Author(s):  
Kevin McKevitt ◽  
Shaheel Sahebally ◽  
Aoibhlinn O’Toole ◽  
Sinead Galvin ◽  
John Patrick Burke
Keyword(s):  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Comparative Study ◽  
Right Hemicolectomy ◽  
Post Operative Pain ◽  
Laparoscopic Right Hemicolectomy

scholarly journals Post-operative pain after laparoscopic right hemicolectomy for Crohn’s disease: a case control study

2021 ◽  
Vol 84 (2) ◽  
pp. 271-274
Author(s):  
K McKevitt ◽  
S.M. Sahebally ◽  
S Patchett ◽  
A O’Toole ◽  
S Galvin ◽  
...  
Keyword(s):  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Inflammatory Response ◽  
Right Hemicolectomy ◽  
Abdominal Abscess ◽  
Patient Gender ◽  
Pain Scores ◽  
Post Operative Pain ◽  
Equivalent Length ◽  
Laparoscopic Right Hemicolectomy

Aim: Surgery for Crohn’s disease (CD) is characterized by an enhanced inflammatory response. While inflammation can induce hyperalgesia, post-operative pain following surgery for CD has not been characterized. This retrospective study compared a consecutive series of patients undergoing laparoscopic right hemicolectomy for CD and neoplasia performed by a single surgeon. Method: Elective resections performed between Jan-2016 and Aug-2017 managed in an enhanced recovery pathway were eligible for inclusion. Patients were excluded if open surgery was performed, an ileostomy was fashioned, no patient-controlled analgesia (PCA) was used or data were incomplete. Results : 38 cases were included, 20 for neoplasia and 18 for ileocolonic CD. There was no difference in patient gender (P=0.520). CD patients were younger (39.8±2.8 Vs 77.2±2.1 years, P<0.001) but had an equivalent length of resection (312.9±43.5 Vs 283.3±71.7 mm, P=0.915). CD patients had higher pain scores on post-operative day 1 (6.8±0.8 Vs 2.6±1.0, P<0.001), day 2 (5.0±0.5 Vs 1.6±0.9, P<0.001) and day 3 (4.1±0.6 Vs 1.3±0.7, P=0.008). CD patients used their PCA for longer (85.7±16.3 Vs 47.7±4.2 hours, P=0.017) and used a greater total amount of morphine (148.6±33.8 Vs 37.0±7.8 mg, P<0.001). Post-operative CRP was higher in patients with CD on day 1 (P=0.011), day 2 (P=0.001), day 3 (P=0.001) and day 4 (P=0.007), but no leak or intra-abdominal abscess occurred in either group. Results: 38 cases were included, 20 for neoplasia and 18 for ileocolonic CD. There was no difference in patient gender (P=0.520). CD patients were younger (39.8±2.8 Vs 77.2±2.1 years, P<0.001) but had an equivalent length of resection (312.9±43.5 Vs 283.3±71.7 mm, P=0.915). CD patients had higher pain scores on post-operative day 1 (6.8±0.8 Vs 2.6±1.0, P<0.001), day 2 (5.0±0.5 Vs 1.6±0.9, P<0.001) and day 3 (4.1±0.6 Vs 1.3±0.7, P=0.008). CD patients used their PCA for longer (85.7±16.3 Vs 47.7±4.2 hours, P=0.017) and used a greater total amount of morphine (148.6±33.8 Vs 37.0±7.8 mg, P<0.001). Post-operative CRP was higher in patients with CD on day 1 (P=0.011), day 2 (P=0.001), day 3 (P=0.001) and day 4 (P=0.007), but no leak or intra-abdominal abscess occurred in either group. Conclusions: CD patients experience increased post-operative pain, require more post-operative analgesia and have an enhanced post-operative inflammatory response. Further studies to elucidate the mechanism of this hyperalgesia and strategies to obviate it are required.

Laparoscopic ileo-colic resection and right hemicolectomy for Crohn’s disease and colon cancer: a preliminary comparative study on post-operative outcome

2020 ◽  
Vol 72 (3) ◽  
pp. 821-826
Author(s):  
Alessandro Tiberi ◽  
Benedetta Pesi ◽  
Francesco Giudici ◽  
Daniela Zambonin ◽  
Tommaso Nelli ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Comparative Study ◽  
Right Hemicolectomy ◽  
Operative Outcome

Sa595 DIETARY INFLAMMATORY POTENTIAL AND FOOD PATTERNS IN RELATION TO GUT MICROBIOME AMONG CHILDREN WITH CROHN'S DISEASE: A COMPARATIVE STUDY WITH HEALTHY CONTROLS

2021 ◽  
Vol 160 (6) ◽  
pp. S-566
Author(s):  
Jessica Breton ◽  
Vincent Tu ◽  
Ceylan Tanes ◽  
Maire A. Conrad ◽  
Kelly Kachelries ◽  
...  
Keyword(s):  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Comparative Study ◽  
Gut Microbiome ◽  
Healthy Controls ◽  
Food Patterns

Crohn’s disease of the gallbladder

2021 ◽  
Vol 14 (9) ◽  
pp. e243579
Author(s):  
Callam Scott ◽  
Amit Patel ◽  
Noori Maka ◽  
Jonathan C MacDonald
Keyword(s):  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Gallstone Formation ◽  
Right Hemicolectomy ◽  
Chronic Cholecystitis ◽  
Pathological Examination ◽  
Key Factors ◽  
Chronic Inflammatory Condition ◽  
History Of ◽  
Lymphoid Aggregates

Crohn’s disease (CD) is a chronic inflammatory condition, which typically involves the small and large bowel but can affect any part of the gastrointestinal tract. Common symptoms include abdominal pain, diarrhoea, fatigue, weight loss and malnutrition. Complications of CD include gallstone formation and cholecystitis. Impaired reabsorption of bile salts in the small bowel and CD-related surgeries are key factors in the development of CD-related gallstones, although other factors are also important. Direct CD-related inflammation of the gallbladder is very unusual and the typical histological features of CD are rarely encountered in cholecystectomy specimens of individuals with CD. We present a case of a man in his early 60s with CD, previous right hemicolectomy and a history of gallstones, who presented with chronic cholecystitis. Following cholecystectomy, pathological examination of the gallbladder unexpectedly demonstrated typical features of CD, including lymphoid aggregates and non-caseating mucosal granulomata.

scholarly journals Prevalence of Sleep Disturbances in Patients With Crohn's Disease (CD) – A Comparative Study

2011 ◽  
Vol 140 (5) ◽  
pp. S-425-S-426
Author(s):  
Ram Dickman ◽  
Rachel Gingold – Belfer ◽  
Sigal Levy ◽  
Nir Peled ◽  
Gerald Fraser ◽  
...  
Keyword(s):  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Comparative Study ◽  
Sleep Disturbances

Comparative Study of Two Cohorts of Newly Diagnosed Crohn's Disease Demonstrates Change in Therapeutic Strategies

Digestion ◽  
2017 ◽  
Vol 96 (3) ◽  
pp. 135-141 ◽  
Author(s):  
Oded Icht ◽  
Henit Yanai ◽  
Yulia Ron ◽  
Guy Rosner ◽  
Ayala Yaron ◽  
...  
Keyword(s):  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Comparative Study ◽  
Therapeutic Strategies ◽  
Newly Diagnosed
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