scholarly journals Combining the systemic inflammation response index and prognostic nutritional index to predict the prognosis of locally advanced elderly esophageal squamous cell carcinoma patients undergoing definitive radiotherapy

2021 ◽  
Vol 0 (0) ◽  
pp. 0-0
Author(s):  
Ke Yan ◽  
Wanyi Wei ◽  
Wenbin Shen ◽  
Xingyu Du ◽  
Shuchai Zhu ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Esophageal Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Systemic Inflammation ◽  
Squamous Cell ◽  
Locally Advanced ◽  
Prognostic Nutritional Index ◽  
Inflammation Response ◽  
Response Index ◽  
Nutritional Index

The prognostic nutritional index as a predictor of long-term outcome in patients with resected esophageal squamous cell carcinoma

2020 ◽  
Author(s):  
Tsunehiko Maruyama ◽  
Mitsugi Shimoda ◽  
Akihiro Sako ◽  
Hiroyuki Hakoda ◽  
Kazumitsu Ueda ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Esophageal Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Prognostic Nutritional Index ◽  
Long Term Outcome ◽  
Neutrophil Lymphocyte Ratio ◽  
Lymphocyte Ratio ◽  
Nutritional Index

Abstract Background Preoperative nutritional and inflammation indexes have been shown to be associated with postoperative complications and the prognosis of patients with a malignant tumor. We evaluated several clinicopathological prognostic factors in patients with resected esophageal squamous cell carcinoma (ESCC). Methods Seventy-eight patients who underwent curative resection for ESCC were included in this retrospective study. The associations of body mass index (BMI), the prognostic nutritional index (PNI), neutrophil-lymphocyte ratio (NLR), platelet-lymphocyte ratio (PLR), and protein-albumin ratio (CAR) with various clinicopathological factors were evaluated. Results In multivariate analyses, only low PNI (<46.8) independently and significantly predicted overall survival (OS) (P=0.002). Conclusions The PNI is a simple, useful marker for predicting the long-term prognosis of patients with ESCC after esophagectomy. The PNI should be included in the routine assessment of patients with ESCC.

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