scholarly journals Molecular mechanisms of right ventricular dysfunction in pulmonary arterial hypertension: focus on the coronary vasculature, sex hormones, and glucose/lipid metabolism

2020 ◽  
Vol 10 (5) ◽  
pp. 1522-1540
Author(s):  
Vineet Agrawal ◽  
Tim Lahm ◽  
Georg Hansmann ◽  
Anna R. Hemnes
Keyword(s):  
Lipid Metabolism ◽  
Pulmonary Arterial Hypertension ◽  
Arterial Hypertension ◽  
Right Ventricular ◽  
Sex Hormones ◽  
Molecular Mechanisms ◽  
Ventricular Dysfunction ◽  
Right Ventricular Dysfunction ◽  
Coronary Vasculature ◽  
Pulmonary Arterial

scholarly journals Treatment of right ventricular dysfunction and heart failure in pulmonary arterial hypertension

2020 ◽  
Vol 10 (5) ◽  
pp. 1659-1674
Author(s):  
Chakradhari Inampudi ◽  
Ryan J. Tedford ◽  
Anna R. Hemnes ◽  
Georg Hansmann ◽  
Harm-Jan Bogaard ◽  
...  
Keyword(s):  
Heart Failure ◽  
Pulmonary Arterial Hypertension ◽  
Arterial Hypertension ◽  
Right Ventricular ◽  
Ventricular Dysfunction ◽  
Right Ventricular Dysfunction ◽  
Pulmonary Arterial

scholarly journals Right Ventricular Dysfunction and Failure in Chronic Pressure Overload

2011 ◽  
Vol 2011 ◽  
pp. 1-7 ◽  
Author(s):  
Marc A. Simon ◽  
Michael R. Pinsky
Keyword(s):  
Pulmonary Arterial Hypertension ◽  
Arterial Hypertension ◽  
Right Ventricular ◽  
Cause Of Death ◽  
Ventricular Dysfunction ◽  
Pressure Overload ◽  
Right Ventricular Dysfunction ◽  
Current Understanding ◽  
Diagnosis And Treatment ◽  
Pulmonary Arterial

Right ventricular (RV) dysfunction is the main cause of death in pulmonary arterial hypertension (PAH). Our understanding of the pathophysiology of RV dysfunction is limited but improving. Methods to better diagnose RV dysfunction earlier and treatments specifically designed to minimize or reverse the remodeling process are likely to improve outcomes. We review the current understanding of RV dysfunction in chronic pressure overload and introduce some novel insights based on recent investigations into pathophysiology, diagnosis, and treatment.

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