scholarly journals Left ventricular strains correlate with aortic elastic properties in adult patients with corrected tetralogy of Fallot (Results from the CSONGRAD Registry and MAGYAR-Path Study)

2021 ◽  
Vol 11 (2) ◽  
pp. 611-622
Author(s):  
Gergely Rácz ◽  
Árpád Kormányos ◽  
Péter Domsik ◽  
Anita Kalapos ◽  
Nándor Gyenes ◽  
...  
Keyword(s):  
Tetralogy Of Fallot ◽  
Elastic Properties ◽  
Left Ventricular ◽  
Adult Patients ◽  
Aortic Elastic Properties

Left ventricular rotational abnormalities in adult patients with corrected tetralogy of Fallot following different surgical procedures – a three-dimensional speckle-tracking echocardiographic study

2020 ◽  
Vol 41 (Supplement_2) ◽  
Author(s):  
A Nemes ◽  
G Racz ◽  
A Kormanyos ◽  
P Domsik ◽  
A Kalapos ◽  
...  
Keyword(s):  
Tetralogy Of Fallot ◽  
Elastic Properties ◽  
Speckle Tracking ◽  
Aortic Stiffness ◽  
Three Dimensional ◽  
Left Ventricular ◽  
Total Correction ◽  
Apical Rotation ◽  
Rotational Mechanics ◽  
Aortic Elastic Properties

Abstract Introduction Tetralogy of Fallot (TOF) is the most common cyanotic congenital heart disease. Abnormal aortic dimensions and elasticity parameters have been long described for corrected TOF (cTOF) together with left ventricular (LV) rotational abnormalities. The present study focuses on investigating LV rotational mechanics in cTOF, and possible correlation of these parameters with aortic elastic properties. It was also aimed to be examined whether different surgical strategies has any effect on the results. Methods The study involved 26 adult cTOF patients, from which 14 had palliative surgery first [Blaloc-Taussig (n=10), Waterstone-Cooley (n=2) shunts, or Brock procedure (n=2)] (mean age at the repair: 7.3±10.2 years) and a late total correction (mean age at the repair: 10.0±13.3 years) (pcTOF), while the early total correction was the treatment of choice in 12 patients (mean age at the repair: 4.2±3.2 years) (etrTOF). Their results were compared to that of 37 age- and gender-matched healthy adults. Routine transthoracic two-dimensional Doppler echocardiography extended with assessment of aortic elastic properties and three-dimensional speckle-tracking echocardiography (3DSTE) was performed in all cTOF patients and controls. Results Sixteen out of 26 cTOF patients showed normally directed LV rotational mechanics, while apical and basal LV rotations were in the same clockwise and counterclockwise directions in 7 and 3 cTOF cases, respectively (38%). This sort of LV movement is called as LV rigid body rotation (RBR). The ratio of LV-RBR between etrTOF and pcTOF patients did not differ significantly (33% vs. 43%, p=0.70). Significantly reduced LV apical rotation (5.2±3.7 degree vs. 10.2±4.5 degree, p<0.05) and twist (9.0±3.3 degree vs. 14.6±4.9 degree, p<0.05) could be demonstrated in cTOF patients with normally directed LV rotational mechanics with preserved LV basal rotation regardless of previous procedure. pcTOF patients showed significantly reduced LV apical rotation as compared to that of etrTOF cases (3.2±3.7 degree vs. 7.1±2.5 degree, p<0.05). From the 7 cTOF patients with clockwise LV-RBR, apical and basal LV rotation proved to be −6.8±5.4 degree and −4.9±2.4 degree, respectively with LV apico-basal gradient of 4.3±3.6 degree. The mean LV apical and basal LV rotation of 3 cTOF patients with counterclockwise LV-RBR prove to be −2.1±3.4 degree and 0.2±0.9 degree, respectively with LV apico-basal gradient of 2.5±2.4 degree. Significant correlations could be demonstrated between LV apical rotation and aortic stiffness index (r=−0.55, p=0.03) and aortic distensibility (r=0.52, p=0.04). Conclusions Significant LV rotational abnormalities could be demonstrated in cTOF with the high prevalence of LV-RBR. cTOF patients with early total reconstruction proved to have beneficial results. Abnormal physiologic response of LV rotational mechanics to increased aortic stiffness can be detected in cTOF patients without LV-RBR. Funding Acknowledgement Type of funding source: None

scholarly journals 2111Prognostic value of left ventricular rotation and strain in adult patients with repaired tetralogy of Fallot

2018 ◽  
Vol 39 (suppl_1) ◽  
Author(s):  
R W J Van Grootel ◽  
A E Van Den Bosch ◽  
V J M Baggen ◽  
M E Menting ◽  
J A A E Cuypers ◽  
...  
Keyword(s):  
Tetralogy Of Fallot ◽  
Left Ventricular ◽  
Adult Patients ◽  
Repaired Tetralogy Of Fallot

scholarly journals Abnormal left ventricular rotation and twist in adult patients with corrected tetralogy of Fallot

2013 ◽  
Vol 15 (5) ◽  
pp. 566-574 ◽  
Author(s):  
M. E. Menting ◽  
J. A. Eindhoven ◽  
A. E. van den Bosch ◽  
J. A. A. E. Cuypers ◽  
T. P. E. Ruys ◽  
...  
Keyword(s):  
Tetralogy Of Fallot ◽  
Left Ventricular ◽  
Adult Patients

scholarly journals Left ventricular abnormal rotation and twist in adult patients with corrected tetralogy of fallot

2013 ◽  
Vol 34 (suppl 1) ◽  
pp. P2090-P2090 ◽  
Author(s):  
M. E. Menting ◽  
A. E. Van Den Bosch ◽  
J. A. Eindhoven ◽  
J. A. A. E. Cuypers ◽  
T. P. E. Ruys ◽  
...  
Keyword(s):  
Tetralogy Of Fallot ◽  
Left Ventricular ◽  
Adult Patients
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