Ensartinib (X-396) a novel drug for anaplastic lymphoma kinase-positive non-small cell lung cancer patients: we need smart trials to avoid wasting good bullets

Gianluca Spitaleri; Antonio Passaro; Filippo de Marinis

doi:10.21037/cco.2018.09.03

Ensartinib (X-396) a novel drug for anaplastic lymphoma kinase-positive non-small cell lung cancer patients: we need smart trials to avoid wasting good bullets

Chinese Clinical Oncology ◽

10.21037/cco.2018.09.03 ◽

2019 ◽

Vol 8 (S1) ◽

pp. S1-S1 ◽

Cited By ~ 2

Author(s):

Gianluca Spitaleri ◽

Antonio Passaro ◽

Filippo de Marinis

Keyword(s):

Lung Cancer ◽

Small Cell Lung Cancer ◽

Cancer Patients ◽

Cell Lung Cancer ◽

Anaplastic Lymphoma Kinase ◽

Small Cell ◽

Small Cell Lung ◽

Lung Cancer Patients ◽

Anaplastic Lymphoma ◽

Novel Drug

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Immunohistochemical screening for anaplastic lymphoma kinase (ALK) rearrangement in advanced non-small cell lung cancer patients

Lung Cancer ◽

10.1016/j.lungcan.2012.03.004 ◽

2012 ◽

Vol 77 (2) ◽

pp. 288-292 ◽

Cited By ~ 79

Author(s):

Heae Surng Park ◽

June Koo Lee ◽

Dong-Wan Kim ◽

Kimary Kulig ◽

Tae Min Kim ◽

...

Keyword(s):

Lung Cancer ◽

Small Cell Lung Cancer ◽

Cancer Patients ◽

Cell Lung Cancer ◽

Anaplastic Lymphoma Kinase ◽

Small Cell ◽

Small Cell Lung ◽

Alk Rearrangement ◽

Lung Cancer Patients ◽

Anaplastic Lymphoma

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PROFILing non-small-cell lung cancer patients for treatment with crizotinib according to anaplastic lymphoma kinase abnormalities: translating science into medicine

Expert Opinion on Pharmacotherapy ◽

10.1517/14656566.2013.778828 ◽

2013 ◽

Vol 14 (5) ◽

pp. 597-608 ◽

Cited By ~ 4

Author(s):

Sara Pilotto ◽

Umberto Peretti ◽

Silvia Novello ◽

Giulio Rossi ◽

Michele Milella ◽

...

Keyword(s):

Lung Cancer ◽

Small Cell Lung Cancer ◽

Cancer Patients ◽

Cell Lung Cancer ◽

Anaplastic Lymphoma Kinase ◽

Small Cell ◽

Small Cell Lung ◽

Lung Cancer Patients ◽

Anaplastic Lymphoma

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P1.14-32 Rash and Efficacy in Anaplastic Lymphoma Kinase Positive (ALK+) Non-Small Cell Lung Cancer Patients Treated with Ensartinib

Journal of Thoracic Oncology ◽

10.1016/j.jtho.2019.08.1183 ◽

2019 ◽

Vol 14 (10) ◽

pp. S566

Author(s):

H. Wakelee ◽

K. Reckamp ◽

T. Leal ◽

A. Chiappori ◽

S. Waqar ◽

...

Keyword(s):

Lung Cancer ◽

Small Cell Lung Cancer ◽

Cancer Patients ◽

Cell Lung Cancer ◽

Anaplastic Lymphoma Kinase ◽

Small Cell ◽

Small Cell Lung ◽

Lung Cancer Patients ◽

Anaplastic Lymphoma

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EP1.01-03 Real World Outcome of Crizotinib for Anaplastic Lymphoma Kinase-Positive Non-Small Cell Lung Cancer Patients

Journal of Thoracic Oncology ◽

10.1016/j.jtho.2019.08.1975 ◽

2019 ◽

Vol 14 (10) ◽

pp. S911

Author(s):

C. Choi ◽

Y.J. Kim ◽

J.C. Lee ◽

S. Kim ◽

D.H. Lee ◽

...

Keyword(s):

Lung Cancer ◽

Small Cell Lung Cancer ◽

Cancer Patients ◽

Cell Lung Cancer ◽

Real World ◽

Anaplastic Lymphoma Kinase ◽

Small Cell ◽

Small Cell Lung ◽

Lung Cancer Patients ◽

Anaplastic Lymphoma

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J-ALEX trial will crown alectinib as the standard choice for anaplastic lymphoma kinase positive untreated non-small cell lung cancer patients?

Journal of Thoracic Disease ◽

10.21037/jtd.2017.12.76 ◽

2018 ◽

Vol 10 (1) ◽

pp. 106-108 ◽

Cited By ~ 3

Author(s):

Cesare Gridelli ◽

Francesca Casaluce ◽

Assunta Sgambato ◽

Giovanni Palazzolo ◽

Paolo Maione

Keyword(s):

Lung Cancer ◽

Small Cell Lung Cancer ◽

Cancer Patients ◽

Cell Lung Cancer ◽

Anaplastic Lymphoma Kinase ◽

Small Cell ◽

Small Cell Lung ◽

Lung Cancer Patients ◽

Anaplastic Lymphoma

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Anaplastic lymphoma kinase immunohistochemistry scores do not predict sensitivity to crizotinib in fluorescence in situ hybridization-positive non-small cell lung cancer patients

The International Journal of Biological Markers ◽

10.1177/1724600818754763 ◽

2018 ◽

Vol 33 (4) ◽

pp. 549-550

Author(s):

Giulio Metro ◽

Diana Giannarelli ◽

Angelo Sidoni ◽

Rita Chiari ◽

Guido Bellezza

Keyword(s):

Lung Cancer ◽

In Situ Hybridization ◽

Small Cell Lung Cancer ◽

Cancer Patients ◽

Anaplastic Lymphoma Kinase ◽

Small Cell ◽

Small Cell Lung ◽

Lung Cancer Patients ◽

Anaplastic Lymphoma

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eXalt3: Phase III randomized study comparing ensartinib to crizotinib in anaplastic lymphoma kinase positive non-small cell lung cancer patients

Annals of Oncology ◽

10.1093/annonc/mdy292.121 ◽

2018 ◽

Vol 29 ◽

pp. viii543

Author(s):

L. Horn ◽

Y.-L. Wu ◽

M. Reck ◽

H. Wakelee ◽

C. Liang ◽

...

Keyword(s):

Lung Cancer ◽

Small Cell Lung Cancer ◽

Cancer Patients ◽

Anaplastic Lymphoma Kinase ◽

Randomized Study ◽

Small Cell ◽

Phase Iii ◽

Small Cell Lung ◽

Lung Cancer Patients ◽

Anaplastic Lymphoma

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Abstract 1718: Favorable clinical outcomes of pemetrexed treatment in anaplastic lymphoma kinase positive non-small-cell lung cancer patients were associated with low expression of thymidylate synthase in tumor

10.1158/1538-7445.am2012-1718 ◽

2012 ◽

Author(s):

Ha Yeon Lee ◽

Hee Kyung Ahn ◽

Ji Yun Jeong ◽

Mi Jung Kwon ◽

Jung-Ho Han ◽

...

Keyword(s):

Lung Cancer ◽

Small Cell Lung Cancer ◽

Cancer Patients ◽

Thymidylate Synthase ◽

Anaplastic Lymphoma Kinase ◽

Small Cell ◽

Small Cell Lung ◽

Lung Cancer Patients ◽

Anaplastic Lymphoma ◽

Low Expression

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P1.13-02 eXalt3: Phase 3 Randomized Study Comparing Ensartinib to Crizotinib in Anaplastic Lymphoma Kinase Positive Non-Small Cell Lung Cancer Patients

Journal of Thoracic Oncology ◽

10.1016/j.jtho.2018.08.858 ◽

2018 ◽

Vol 13 (10) ◽

pp. S582 ◽

Cited By ~ 1

Author(s):

L. Horn ◽

Y. Wu ◽

M. Reck ◽

H. Wakelee ◽

C. Liang ◽

...

Keyword(s):

Lung Cancer ◽

Small Cell Lung Cancer ◽

Cancer Patients ◽

Anaplastic Lymphoma Kinase ◽

Randomized Study ◽

Small Cell ◽

Small Cell Lung ◽

Phase 3 ◽

Lung Cancer Patients ◽

Anaplastic Lymphoma

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Exposure–Response Analyses of Anaplastic Lymphoma Kinase Inhibitors Crizotinib and Alectinib in Non‐Small Cell Lung Cancer Patients

Clinical Pharmacology & Therapeutics ◽

10.1002/cpt.1989 ◽

2020 ◽

Cited By ~ 1

Author(s):

Stefanie L. Groenland ◽

Dieuwertje R. Geel ◽

Julie M. Janssen ◽

Niels Vries ◽

Hilde Rosing ◽

...

Keyword(s):

Lung Cancer ◽

Small Cell Lung Cancer ◽

Cancer Patients ◽

Anaplastic Lymphoma Kinase ◽

Kinase Inhibitors ◽

Small Cell ◽

Small Cell Lung ◽

Lung Cancer Patients ◽

Anaplastic Lymphoma ◽

Exposure Response

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