scholarly journals Red blood cell distribution width independently predicts medium-term mortality and major adverse cardiac events after an acute coronary syndrome

2016 ◽  
Vol 4 (13) ◽  
pp. 254-254 ◽  
Author(s):  
Gianni Turcato ◽  
Valentina Serafini ◽  
Alice Dilda ◽  
Chiara Bovo ◽  
Beatrice Caruso ◽  
...  
Keyword(s):  
Acute Coronary Syndrome ◽  
Blood Cell ◽  
Red Blood Cell ◽  
Cell Distribution ◽  
Cardiac Events ◽  
Medium Term ◽  
Distribution Width ◽  
Coronary Syndrome ◽  
Adverse Cardiac Events ◽  
Red Blood Cell Distribution

scholarly journals HIGH RED BLOOD CELL DISTRIBUTION WIDTH IS ASSOCIATED WITH THE PRESENCE OF ACUTE CORONARY SYNDROME

2015 ◽  
Vol 65 (10) ◽  
pp. A252
Author(s):  
Ryo Nishio ◽  
Satoru Kawasaki ◽  
Takeo Tanaka ◽  
Hiroyuki Kawamori ◽  
Toshimitsu Ishii ◽  
...  
Keyword(s):  
Acute Coronary Syndrome ◽  
Blood Cell ◽  
Red Blood Cell ◽  
Cell Distribution ◽  
Distribution Width ◽  
Coronary Syndrome ◽  
Red Blood Cell Distribution

The role of plateletcrit and red blood cell distribution width as a predictor of in-hospital mortality in patients with acute coronary syndrome

2020 ◽  
Vol 41 (Supplement_2) ◽  
Author(s):  
A Sudharsono ◽  
D Khairina ◽  
A Fajar Muzakkir ◽  
A Hakim Alkatiri ◽  
M.Z Muzakkir Amir
Keyword(s):  
Acute Coronary Syndrome ◽  
Blood Cell ◽  
Hospital Mortality ◽  
Red Blood Cell ◽  
Cell Distribution ◽  
Distribution Width ◽  
Coronary Syndrome ◽  
Grace Score ◽  
Red Blood Cell Distribution

Abstract Introduction Red Blood Cell Distribution Width (RDW CV) and Plateletcrit (PCT) are part of complete blood count (CBC) examination. There are few studies have been reported the use of these parameters to predict clinical outcome including mortality, but none of them conducted in Asian population. We seek to investigate the role of PCT and RDW CV as a potential objective biomarker to predict in hospital mortality coincide with Global Registry of Acute Cardiac Events (GRACE) score in Acute Coronary Syndrome (ACS). Methods We respectively analysed patients with ACS who were admitted to the coronary care unit between June 2018 and December 2019. The GRACE and CBC were taken consecutively. Results A total of 1053 patients with ACS (46% non-ST elevated ACS (NSTE-ACS) and 54% ST elevated myocardial infarction (STEMI)] were enrolled in this study. PCT and RDW-CV was found to be significantly correlated with mortality (p<0.001). Further analysis showed significant higher level of PCT in patients with event compared to the other group (0.32 vs 0.24, p<0.001). Similar result was found for RDW (14.1 vs 13.2, p<0.001). ROC curve analysis for PCT and RDW-CV levels showed an AUC of 0.65, (cut off value: 0.25. p<0.001) and 0.69 (cut off value 13.05, p<0.001), respectively. High PCT and RDW-CV level were found to be a good predictor of mortality in ACS patients. (OR 2.6 and OR 3.4 respectively, p<0.001) In patients with high risk GRACE risk categories, we found a significantly higher levels of PCT (0.27 vs 0.24, p<0.001) and RDW-CV (13.8 vs 13.2, p<0.001) compared to low-intermediate risk group. Conclusion(s) We found that both PCT and RDW-CV may act as novel and promising tool to predict in hospital mortality directly proportional with GRACE Score among ACS patient. Figure 1. ROC curve for PCT and RDW-CV. Funding Acknowledgement Type of funding source: None

scholarly journals In-hospital evolution of red blood cell distribution with value and prognosis in patients with acute coronary syndrome

2013 ◽  
Vol 34 (suppl 1) ◽  
pp. P3091-P3091
Author(s):  
C. Vieira ◽  
S. Nabais ◽  
V. Ramos ◽  
C. Galvao Braga ◽  
J. Martins ◽  
...  
Keyword(s):  
Acute Coronary Syndrome ◽  
Blood Cell ◽  
Red Blood Cell ◽  
Cell Distribution ◽  
Coronary Syndrome ◽  
Red Blood Cell Distribution

scholarly journals The Prognostic Role of Red Blood Cell Distribution Width in Coronary Artery Disease: A Review of the Pathophysiology

2015 ◽  
Vol 2015 ◽  
pp. 1-12 ◽  
Author(s):  
Kamil Bujak ◽  
Jarosław Wasilewski ◽  
Tadeusz Osadnik ◽  
Sandra Jonczyk ◽  
Aleksandra Kołodziejska ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Bone Marrow ◽  
Coronary Artery ◽  
Blood Cell ◽  
Red Blood Cell ◽  
Cell Distribution ◽  
Distribution Width ◽  
Coronary Syndrome ◽  
Artery Disease ◽  
Red Blood Cell Distribution

Red blood cell distribution width (RDW) is a measure of red blood cell volume variations (anisocytosis) and is reported as part of a standard complete blood count. In recent years, numerous studies have noted the importance of RDW as a predictor of poor clinical outcomes in the settings of various diseases, including coronary artery disease (CAD). In this paper, we discuss the prognostic value of RDW in CAD and describe the pathophysiological connection between RDW and acute coronary syndrome. In our opinion, the negative prognostic effects of elevated RDW levels may be attributed to the adverse effects of independent risk factors such as inflammation, oxidative stress, and vitamin D3and iron deficiency on bone marrow function (erythropoiesis). Elevated RDW values may reflect the intensity of these phenomena and their unfavorable impacts on bone marrow erythropoiesis. Furthermore, decreased red blood cell deformability among patients with higher RDW values impairs blood flow through the microcirculation, resulting in the diminution of oxygen supply at the tissue level, particularly among patients suffering from myocardial infarction treated with urgent revascularization.

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