A right single-lung transplantation performed by Prof. em Dr. Fritz Derom at the University Hospital in Ghent, Belgium on 14th November 1968 in patient Aloïs Vereecken who suffered from end-stage lung fibrosis

ASVIDE ◽  
2017 ◽  
Vol 4 ◽  
pp. 583-583
Author(s):  
Federico Venuta ◽  
Dirk Van Raemdonck
2013 ◽  
Vol 154 (22) ◽  
pp. 868-871 ◽  
Author(s):  
György Lang ◽  
Krisztina Czebe ◽  
Balázs Gieszer ◽  
Ferenc Rényi-Vámos

When conservative treatment fails, lung transplantation often remains the only therapeutic option for patients with end stage parenchymal or vascular lung diseases. According to the statistics of the International Society for Heart and Lung Transplantation, in 2010 more than 3500 lung transplantations have been performed worldwide. The Department of Thoracic Surgery at the University of Vienna is considered to be one of the world’s leading lung transplantation centres; in the last year 115, since 1989 more than 1500 lung transplantation procedures under the supervision of Prof. Dr. Walter Klepetko. Similar to other Central-European countries, lung transplantation procedures of Hungarian patients have also been performed in Vienna whithin the framework of a twinning aggreement. However, many crucial tasks in the process, such indication and patient selection preoperative rehabilitation organ procurement and long term follow-up care have been stepwise taken over by the Hungarian team. Although the surgery itself is still preformed in Vienna, professional experience is already available in Hungary, since the majority of Hungarian recipients have been transplanted by hungarian surgeons who are authors of this article the professional and personal requirements of performing lung transplantations are already available in Hungary. The demand of performing lung transplantation in Hungary has been raising since 1999 and it soon reaches the extent which justifies launching of an individual national program. Providing the technical requirements is a financial an organisational issue. In order to proceed, a health policy decision has to be made. Orv. Hetil., 2013, 154, 868–871.


Thorax ◽  
1995 ◽  
Vol 50 (5) ◽  
pp. 562-564 ◽  
Author(s):  
N P Briffa ◽  
C Dennis ◽  
T Higenbottam ◽  
S A Nashef ◽  
S R Large ◽  
...  

Author(s):  
Kajetan Kiełbowski ◽  
Nikola Ruszel ◽  
Seweryn Skrzyniarz ◽  
Maria Piotrowska ◽  
Tomasz Grodzki ◽  
...  

Introduction: Single lung transplantation (SLuTx) is a challenging operation for patients with end-stage chronic pulmonary diseases. After surgery, native lung hyperinflation (NLH) and a mediastinal shift may develop, which changes the anatomical position of the lungs and heart and may lead to graft compression. Aim: We present a case report of a patient who developed NLH after SLuTx. We discuss the treatment methods and compare the outcomes with other case reports and analysis from world literature. Case study: A 56-year-old female patient was diagnosed with end-stage chronic obstructive pulmonary disease (FEV1 < 30%) and qualified for right SLuTx. After the procedure, spirometry revealed gradual loss in FEV1. Radiological images confirmed NLH and compression of the graft. Therefore, a native lung pneumonectomy was performed with positive outcomes. Results and discussion: NLH is a known complication of SLuTx. Typically, lung volume reduction surgery is performed to reduce the compression and a pneumonectomy is a rare treatment, even in centres with extensive experience with SLuTx. Conclusions: Despite SLuTx being a common approach in many pulmonary diseases, NLH should be always taken into consideration. Hyperinflation could cause a dangerous loss of respiratory efficiency and require invasive surgeries for lung transplant recipients.


2022 ◽  
Vol 16 (1) ◽  
Author(s):  
Tiphaine Goletto ◽  
Sixtine Decaux ◽  
Vincent Bunel ◽  
Gaëlle Weisenburger ◽  
Jonathan Messika ◽  
...  

Abstract Background In patients receiving single lung transplantation for idiopathic pulmonary fibrosis, worsening of fibrosis of the native lung is usually progressive over time, with no significant effects on gas exchange. Case presentation Here, we describe the cases of two Caucasian male recipients of single lung transplants for idiopathic pulmonary fibrosis, 65 and 62 years of age, who exhibited acute worsening of lung fibrosis after an episode of serious viral infection (cytomegalovirus primo-infection in one case and COVID-19 in the other). In both cases, along with opacification of the native lung over several days, the patients presented acute respiratory failure that required the use of high-flow nasal oxygen therapy. Eventually, hypoxemic respiratory failure resolved, but with rapid progression of fibrosis of the native lung. Conclusion We conclude that acute worsening of fibrosis on the native lung secondary to a severe viral infection should be added to the list of potential complications developing on the native lung after single lung transplantation for idiopathic pulmonary fibrosis.


Heart ◽  
1991 ◽  
Vol 66 (6) ◽  
pp. 431-434 ◽  
Author(s):  
J C Doig ◽  
P A Corris ◽  
C J Hilton ◽  
J H Dark ◽  
R S Bexton

Author(s):  
Tobias Moest ◽  
Rainer Lutz ◽  
Arne Eric Jahn ◽  
Katharina Heller ◽  
Mario Schiffer ◽  
...  

Abstract Objectives This retrospective study evaluates intraoral surgical and conservative treatment need in patients with a chronic kidney end-stage disease, depending on the duration of dialysis treatment and the causative nephrological disease. Material and methods This study is based on data of patients referred to the Department of Oral and Maxillofacial Surgery of the University Hospital Erlangen, Germany, prior to kidney transplantation between January 2015 and March 2020. The necessity for oral surgical or dental therapy was determined by clinical and radiological examinations. Data on renal replacement therapy, cause of underlying renal disease, lifestyle, and general health were collected. Results Data of N = 89 patients demonstrated that surgical treatment need depends on dialysis duration (p = 0.042). Patients, who had been dialyzing for 2 to 3 years showed the highest need for surgical intervention (80.0%; p = 0.024), followed by dialysis patients with a dialysis time of more than 3 years (48.1%). Similarly, dialysis patients in the second or third year of dialysis had the highest need for conservative treatment (73.3%; p > 0.05), followed by 55.6% of dialysis patients in the third year of dialysis. Conclusions Operative and conservative treatment is essential to optimize subsequent kidney transplantation. The greatest necessity could be detected for patients in the second and third years of dialysis. Clinical relevance Oral health addressing surgical and conservative treatment need depends on the duration of dialysis in patients with a chronic kidney end-stage disease.


2020 ◽  
Vol 1 (1) ◽  
Author(s):  
Hiba El Oury ◽  
Fatim-zahra Jabrane ◽  
Mohamed Amine Khalfaoui ◽  
M Sabah ◽  
G Medkouri

Introduction:  Coronavirus disease 2019: COVID 19, is a new communicable disease caused by the SARS-CoV-2 virus, which appeared in Wuhan, Hubei Province, China in December 2019, and declared a global pandemic on March 11, 2020, by the World Health Organization (WHO). This disease is generally manifested by damage to the airways, most often of a mild form, but can be complicated by acute respiratory distress syndrome. Patients with end-stage renal disease are at high risk of contracting the infection, due to their co-morbidities, the state of immunosuppression and the logistical aspect of the provision of care requiring physical movement of patients to the center dialysis.Objectives of this study: This study aims to assess the knowledge, attitude and perception, in terms of the 2019 coronavirus pandemic, of a sample of patients with chronic end-stage renal disease hemodialysis at the nephrology and dialysis center at the university hospital Cheikh Khalifa Ibn Zaid , in Casablanca, where positive COVID 19 patients were hospitalized and treated during the pandemic.Design: The investigation began after the decree of compulsory confinement and the state of health emergency by the Moroccan government. Awareness sessions, for patients and their family members, were led by nursing staff at the start of the period and during the COVID 19 pandemic. The measuring instrument used was a self-administered questionnaire, 1 month after the start of confinement, with 25 patients with chronic end-stage renal disease on hemodialysis at the rate of 3 sessions per week, at the nephrology and dialysis center at the university hospital. Sheikh Khalifa Ibn Zaid. This questionnaire was carried out after a review of the literature and included 4 headings: a) socio-demographic data b) general knowledge of COVID19 disease c) the attitude of hemodialysis patients outside and inside the dialysis center d) and their perception of this pandemic.Results : The majority of our patients were fairly well informed about the clinical presentation, the means of transmission and the prevention measures against coronavirus 2019. The means of protection were respected outside and in the university hospital center. There were no positive COVID 19 cases among our patients. Despite all the measures taken, the concern of contacting the virus was raised by most patients, especially in the hospital, during the dialysis session and in contact with medical personnel.Conclusion: Given the rapid spread and severe progression of COVID 19, it seems prudent that this profile of patients with end-stage chronic renal failure be included in high-risk populations with close medical and also psychological monitoring, tests screening and awareness and support sessions.


2002 ◽  
Vol 25 (5) ◽  
pp. 401-410 ◽  
Author(s):  
Z. Mitrev ◽  
V. Cvetanovski ◽  
N. Hristov ◽  
G. Petrusevska

Patients with terminal end-stage heart failure due to severe coronary disease associated with dilatative cardiomyopathy have an annual mortality of 30–50%. Between July 1997 and December 1999, 21 patients at the University Hospital in Frankfurt, and 25 patients from Skopje underwent total circular repair with simultaneous coronary artery bypass.


1989 ◽  
Vol 98 (3) ◽  
pp. 350-354 ◽  
Author(s):  
C.G.A. McGregor ◽  
J.H. Dark ◽  
C.J. Hilton ◽  
R. Freeman ◽  
I.D. Conacher ◽  
...  

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