scholarly journals Stereotactic body radiation therapy versus multi-fraction radiation therapy for bone metastases

2019 ◽  
Vol 8 (4) ◽  
pp. 360-363
Author(s):  
Charles B. Simone II
Keyword(s):  
Radiation Therapy ◽  
Bone Metastases ◽  
Stereotactic Body Radiation Therapy ◽  
Stereotactic Body Radiation

Radiological changes on CT after stereotactic body radiation therapy to non-spine bone metastases: a descriptive series

2016 ◽  
Vol 5 (2) ◽  
pp. 116-124 ◽  
Author(s):  
Nicholas Chiu ◽  
Linda Probyn ◽  
Srinivas Raman ◽  
Rachel McDonald ◽  
Ian Poon ◽  
...  
Keyword(s):  
Radiation Therapy ◽  
Bone Metastases ◽  
Stereotactic Body Radiation Therapy ◽  
Stereotactic Body Radiation ◽  
Radiological Changes

scholarly journals Changes in Volume and Density Parameters Measured on Computed Tomography Images Following Stereotactic Body Radiation Therapy of Nonspine Bone Metastases

2019 ◽  
Vol 18 ◽  
pp. 153303381985353
Author(s):  
Samuel Finkelstein ◽  
Srinivas Raman ◽  
Joanne Van Der Velden ◽  
Liying Zhang ◽  
Carolyn Tan ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Radiation Therapy ◽  
Soft Tissue ◽  
Bone Metastases ◽  
Treatment Response ◽  
Local Control ◽  
Stereotactic Body Radiation Therapy ◽  
Bone Lesions ◽  
Stereotactic Body Radiation ◽  
Soft Tissue Volume

Introduction: Volumetric and density parameters measured from computed tomography scans were investigated for evaluating treatment response of nonspine bone lesions following stereotactic body radiation therapy. Methods: Twenty-three patients treated with stereotactic body radiation therapy to nonspine bone metastases with pre- and post-treatment radiological follow-up with computed tomography imaging were identified in a retrospective review. An expert radiologist classified 26 lesions by type (lytic, sclerotic) and by response. Two independent radiation oncologists created separate contours of the bone and soft tissue lesion volumes. Density and volume were assessed relative to baseline values. Results: For bone-only lesions, all lesions designated as local control decreased in volume or remained within 20% of baseline volumes. Lytic lesions classified as progressive disease exhibited much larger volume increases. Lytic bone lesions showed indications of remineralization with some exhibiting immediate increases in density (1-6 months) and others decreasing initially then increasing back toward baseline between 7 and 12 months. The majority of sclerotic lesions, all classified as local control, decreased slightly in both volume and density. Lesions with both soft tissue and boney involvement resulted in contradictory results when employing both radiological and size parameters for assessing treatment response. Classification was dominated by changes in soft tissue volume, despite associated volume or density changes in the corresponding boney lesion. In contrast, when soft tissue volume changes were minimal (<20% increase), classification appeared to be related primarily to density changes and not bone volume. Conclusions: Volume and density changes show promise as quantitative parameters for classifying treatment responses of nonspine osseous lesions. Further work is required for clarifying how these metrics can be applied to lesions with both boney and soft tissue components.

Stereotactic Body Radiation Therapy for Nonspine Bone Metastases: International Practice Patterns to Guide Treatment Planning

2020 ◽  
Vol 10 (6) ◽  
pp. e452-e460 ◽  
Author(s):  
Timothy K. Nguyen ◽  
Arjun Sahgal ◽  
Roi Dagan ◽  
Wietse Eppinga ◽  
Matthias Guckenberger ◽  
...  
Keyword(s):  
Radiation Therapy ◽  
Bone Metastases ◽  
Treatment Planning ◽  
Stereotactic Body Radiation Therapy ◽  
Practice Patterns ◽  
Stereotactic Body Radiation
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