scholarly journals Successful treatment using targeted therapy, radiotherapy, and intrathecal chemotherapy in a patient with leptomeningeal metastasis with an epidermal growth factor receptor exon 20 insertion mutation: a case report

2021 ◽  
Vol 0 (0) ◽  
pp. 0-0
Author(s):  
Yunfei Ma ◽  
Hui Liu ◽  
Min Zhang ◽  
Bailong Liu ◽  
Qiuhui Ding ◽  
...  
Author(s):  
Padmaj S. Kulkarni ◽  
Girish Phadke ◽  
Mahesh M. Mandolkar ◽  
Sujit Nilegaonkar ◽  
Sonali Deshmukh

<p><span>Adenoid cystic carcinoma (ACC) is primarily found in the salivary glands and rarely at other organs but never reported as liver primary. This is a very rare case of primary ACC of the liver which was not resectable and managed with chemotherapy and targeted therapy. The patient progressed on imatinib (c-kit positive) while responded to chemotherapy and gefitinib (epidermal growth factor receptor mutation absent).</span></p>


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