Sensory reinnervation after mastectomy with implant-based reconstruction

2021 ◽  
Vol 0 ◽  
pp. 0-0
Author(s):  
Anne Warren Peled ◽  
Ziv M. Peled
Keyword(s):  
Sensory Reinnervation

scholarly journals Renal sensory and sympathetic nerves reinnervate the kidney in a similar time-dependent fashion after renal denervation in rats

2013 ◽  
Vol 304 (8) ◽  
pp. R675-R682 ◽  
Author(s):  
Jan Mulder ◽  
Tomas Hökfelt ◽  
Mark M. Knuepfer ◽  
Ulla C. Kopp
Keyword(s):  
Substance P ◽  
Optical Density ◽  
Renal Denervation ◽  
Time Course ◽  
Sympathetic Nerves ◽  
Sensory Nerves ◽  
Sensory Innervation ◽  
Multiple Time ◽  
Sensory Reinnervation ◽  
Renal Sympathetic

Efferent renal sympathetic nerves reinnervate the kidney after renal denervation in animals and humans. Therefore, the long-term reduction in arterial pressure following renal denervation in drug-resistant hypertensive patients has been attributed to lack of afferent renal sensory reinnervation. However, afferent sensory reinnervation of any organ, including the kidney, is an understudied question. Therefore, we analyzed the time course of sympathetic and sensory reinnervation at multiple time points (1, 4, and 5 days and 1, 2, 3, 4, 6, 9, and 12 wk) after renal denervation in normal Sprague-Dawley rats. Sympathetic and sensory innervation in the innervated and contralateral denervated kidney was determined as optical density (ImageJ) of the sympathetic and sensory nerves identified by immunohistochemistry using antibodies against markers for sympathetic nerves [neuropeptide Y (NPY) and tyrosine hydroxylase (TH)] and sensory nerves [substance P and calcitonin gene-related peptide (CGRP)]. In denervated kidneys, the optical density of NPY-immunoreactive (ir) fibers in the renal cortex and substance P-ir fibers in the pelvic wall was 6, 39, and 100% and 8, 47, and 100%, respectively, of that in the contralateral innervated kidney at 4 days, 4 wk, and 12 wk after denervation. Linear regression analysis of the optical density of the ratio of the denervated/innervated kidney versus time yielded similar intercept and slope values for NPY-ir, TH-ir, substance P-ir, and CGRP-ir fibers (all R2 > 0.76). In conclusion, in normotensive rats, reinnervation of the renal sensory nerves occurs over the same time course as reinnervation of the renal sympathetic nerves, both being complete at 9 to 12 wk following renal denervation.

Sensory Reinnervation of Muscles Following Nerve Section and Suture in Cats

1985 ◽  
Vol 10 (3) ◽  
pp. 340-344
Author(s):  
R. W. BANKS ◽  
D. BARKER ◽  
H. G. BROWN
Keyword(s):  
Common Peroneal Nerve ◽  
Muscle Spindles ◽  
Sensory Impairment ◽  
Normal Muscle ◽  
Axon Terminals ◽  
Reflex Action ◽  
Stretch Receptors ◽  
The Common ◽  
Sensory Reinnervation ◽  
Tendon Organ

The common peroneal nerve was transected and repaired by epineurial suture in nine cats. In a further nine the nerve was transected twice and similarly repaired so as to produce a short autograft. Recovery of stretch receptors in peroneus brevis was monitored histologically and physiologically from six to fifty weeks. In recovery after single neurotomy functionally identifiable muscle-spindle and tendon-organ afferents were reduced to 25% and 45% of normal, respectively; after double neurotomy (autograft) both were reduced to about 10% of normal. Muscle spindles were reinnervated with annulospiral terminals, or wholly abnormal fine axon terminals, or both. Recovery evidently entails not only a reduction in number of stretch afferents, but also the making of some incorrect reconnections that presumably result in abnormal proprioceptive feedback and reflex action. When a graft is used the sensory impairment is compounded.

An ulnar parametacarpal perforator flap for volar digital soft tissue reconstruction

2020 ◽  
Vol 45 (8) ◽  
pp. 842-848
Author(s):  
Satoshi Usami ◽  
Kohei Inami ◽  
Yuichi Hirase ◽  
Hiroki Mori
Keyword(s):  
Donor Site ◽  
Perforator Flap ◽  
Soft Tissue Reconstruction ◽  
Level Of Evidence ◽  
Tissue Reconstruction ◽  
The Mean ◽  
Lost To Follow Up ◽  
Pulp Repair ◽  
Sensory Reinnervation

We present outcomes of using a perforator-based ulnar parametacarpal flap in 25 patients for digital pulp defects. These included 17 free transfers to the thumb, index, middle and ring fingers and eight reverse pedicled transfers to the little fingers. This flap includes a dorsal sensory branch of the ulnar nerve, which was sutured to the digital nerve in all transfers. Each flap had one to three reliable perforators (mean 0.44 mm diameter) to the ulnar parametacarpal region and contained at least one perforator within 2 cm proximal to the palmar digital crease. All the 25 flaps survived completely. Twenty-two patients were followed for 15 months (range 12 to 24), and three were lost to follow-up. The mean static and moving two-point discrimination of the flap was 7 mm and 5 mm, respectively. At the donor site, sensory reinnervation was acceptable. We conclude that ulnar parametacarpal perforator flaps offer sensate, thick and glabrous skin for finger pulp repair, all in a single operative field. Level of evidence: IV

scholarly journals Upper limb cortical maps in amputees with targeted muscle and sensory reinnervation

Brain ◽  
2017 ◽  
Vol 140 (11) ◽  
pp. 2993-3011 ◽  
Author(s):  
Andrea Serino ◽  
Michel Akselrod ◽  
Roy Salomon ◽  
Roberto Martuzzi ◽  
Maria Laura Blefari ◽  
...  
Keyword(s):  
Upper Limb ◽  
Cortical Maps ◽  
Sensory Reinnervation

Sensory reinnervation and sensibility after superficial skin wounds in human patients

1987 ◽  
Vol 74 (3) ◽  
pp. 377-382 ◽  
Author(s):  
A. Hermanson ◽  
C.-J. Dalsgaard ◽  
H. Björklund ◽  
U. Lindblom
Keyword(s):  
Skin Wounds ◽  
Superficial Skin ◽  
Sensory Reinnervation

Muscle Flap Mass Preservation by Sensory Reinnervation with End-to-Side Neurorrhaphy: An Experimental Study in Rats

2008 ◽  
Vol 24 (07) ◽  
pp. 479-487 ◽  
Author(s):  
Sumiko Yoshitatsu ◽  
Ken Matsuda ◽  
Kenji Yano ◽  
Ko Hosokawa ◽  
Koichi Tomita
Keyword(s):  
Experimental Study ◽  
Muscle Flap ◽  
Sensory Reinnervation

Sensory reinnervation of cat peroneus brevis muscle spindles after nerve crush

1985 ◽  
Vol 333 (1) ◽  
pp. 131-138 ◽  
Author(s):  
D. Barker ◽  
J.J.A. Scott ◽  
M.J. Stacey
Keyword(s):  
Muscle Spindles ◽  
Nerve Crush ◽  
Peroneus Brevis ◽  
Sensory Reinnervation

Enhanced Sensory Reinnervation of Dental Target Tissues in Rats Following Low Level Laser (LLL) Irradiation

1999 ◽  
Vol 14 (3) ◽  
pp. 177-184 ◽  
Author(s):  
S.M. Khullar ◽  
P. Brodin ◽  
I. Fristad ◽  
I.H. Kvinnsland
Keyword(s):  
Low Level ◽  
Low Level Laser ◽  
Level Laser ◽  
Sensory Reinnervation
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