Maskless Gray Scale Lithography and its 3D Microfluidic Applications

2011 ◽  
Vol 23 (3) ◽  
pp. 426-433 ◽  
Author(s):  
Yoko Yamanishi ◽  
◽  
Takuma Nakano ◽  
Yu Sawada ◽  
Kazuyoshi Itoga ◽  
...  
Keyword(s):  
Cross Section ◽  
Mechanical Stimulation ◽  
Microfluidic Chip ◽  
Zona Pellucida ◽  
Three Dimensional ◽  
Cell Manipulation ◽  
The Novel ◽  
Gray Scale

This paper presents the novel three-dimensional fabrication using maskless exposure equipment and threedimensional (3D) microfluidic cell manipulation uses grayscale data to directly control the exposed photoresist height without using a mask. The 3D microchannel and microvalve were fabricated simply using lowcost exposure and height ranging from 0 to 200 µm. The 3D microvalve prevents liquid leakage when the membrane is closed – difficult to do using conventional 2D photolithography. We removed the oocyte zona pellucida passing through the 3D microchannel whose cross-section is gradually restricted along the path to provide mechanical stimulation omnidirectionally on the oocyte surface. The microfluidic chip may contribute to make high peeled-oocyte throughput effective without damaging the oocytes.

Design and Fabrication of All-in-One Unified Microfluidic Chip for Automation of Embryonic Cell Manipulation

2010 ◽  
Vol 22 (3) ◽  
pp. 371-379 ◽  
Author(s):  
Yoko Yamanishi ◽  
◽  
Shinya Sakuma ◽  
Tomohiro Iyanagi ◽  
Fumihito Arai ◽  
...  
Keyword(s):  
Microfluidic Chip ◽  
Zona Pellucida ◽  
Donor Cell ◽  
Embryonic Cell ◽  
Design Concept ◽  
Cell Manipulation ◽  
Electrical Field ◽  
Basic Functions ◽  
On Chip

We developed a microfluidic chip for automation of cloning process based on a new protocol. The protocol is based on removal of the zona pellucida outside the chip which contributes to simplify on-chip automation of cloning. Then, the oocytes are put into the chip. The design concept of the chip is summarized as follows. (1) The oocyte is cut into two parts. (2) The divided half oocyte is sorted with and without nucleus. (3) The half oocyte without nucleus is coupled with a donor cell, and (4) they are fused by an electrical field. For the current study, the all-in-one unified microfluidic chip was designed to execute (1) cutting, (2) sorting, and (3) coupling parts continuously for this process. Basic functions of these parts as well as fusion part are verified independently. Then, all-in-one unified microfluidic chip was successfully designed and fabricated.

Study on Effects of Novel Cross Sections of Microchannel Heat Sink on Thermohydraulic Performance

2020 ◽  
Vol 142 (4) ◽  
Author(s):  
Abhilash K. Tilak ◽  
Ranjit S. Patil
Keyword(s):  
Cross Section ◽  
Cross Sections ◽  
Three Dimensional ◽  
Constant Heat Flux ◽  
Heat Sinks ◽  
Microchannel Heat Sink ◽  
The Novel ◽  
Cross Sectional ◽  
The Heat Transfer Coefficient ◽  
Three Dimensional Simulations

Abstract In this paper, three-dimensional simulations to study the performance of microchannel heat sinks (MCHS) with rectangular, hexagonal, semicircular and various novel cross section (such as barrel, fan shaped, L shaped, inverted T shaped, inverted T shaped with semicircular ends at base (ITSCEB)) were carried out using de-ionized water. Numerical results were validated with the published experimental data and further simulations were performed on various novel cross section at a constant heat flux of 50 W/cm2 with Reynolds number varying in the range of 300–1500. The comparative analysis of various novel MCHS having the same cross-sectional area was carried out to figure out the suitable cross section capable of better cooling performance. This work shows that the novel ITSCEB cross section was giving the highest pressure drop, however considerable improvement was noted in the heat transfer coefficient around 21% more than conventional rectangular and around 11–55% more than other proposed cross section in this study.

SAF file: It's really three dimensional file

2018 ◽  
Vol 14 (1) ◽  
pp. 1
Author(s):  
Prof. Dr. Jamal Aziz Mehdi
Keyword(s):  
Cross Section ◽  
Root Canal ◽  
Three Dimensional ◽  
Circular Cross Section ◽  
Circular Motion ◽  
Root Canal Treatment ◽  
Metal Core ◽  
Rotating Blade

The biological objectives of root canal treatment have not changed over the recentdecades, but the methods to attain these goals have been greatly modified. Theintroduction of NiTi rotary files represents a major leap in the development ofendodontic instruments, with a wide variety of sophisticated instruments presentlyavailable (1, 2).Whatever their modification or improvement, all of these instruments have onething in common: they consist of a metal core with some type of rotating blade thatmachines the canal with a circular motion using flutes to carry the dentin chips anddebris coronally. Consequently, all rotary NiTi files will machine the root canal to acylindrical bore with a circular cross-section if the clinician applies them in a strictboring manner

ANALYSIS OF THE GENERAL EQUATIONS OF THE TRANSVERSE VIBRATION OF A PIECEWISE UNIFORM VISCOELASTIC PLATE

2020 ◽  
Vol 7 (3) ◽  
pp. 52-56
Author(s):  
MMATMATISA JALILOV ◽  
◽  
RUSTAM RAKHIMOV ◽  
Keyword(s):  
Cross Section ◽  
Transverse Vibration ◽  
Three Dimensional ◽  
Viscoelastic Plate ◽  
Constant Thickness ◽  
Regional Problem ◽  
Rigid Contact ◽  
Under Construction ◽  
Derivatives Of ◽  
Theoretical Results

This article discusses the analysis of the general equations of the transverse vibration of a piecewise homogeneous viscoelastic plate obtained in the “Oscillation of inlayer plates of constant thickness” [1]. In the present work on the basis of a mathematical method, the approached theory of fluctuation of the two-layer plates, based on plate consideration as three dimensional body, on exact statement of a three dimensional mathematical regional problem of fluctuation is stood at the external efforts causing cross-section fluctuations. The general equations of fluctuations of piecewise homogeneous viscoelastic plates of the constant thickness, described in work [1], are difficult on structure and contain derivatives of any order on coordinates x, y and time t and consequently are not suitable for the decision of applied problems and carrying out of engineering calculations. For the decision of applied problems instead of the general equations it is expedient to use confidants who include this or that final order on derivatives. The classical equations of cross-section fluctuation of a plate contain derivatives not above 4th order, and for piecewise homogeneous or two-layer plates the elementary approached equation of fluctuation is the equation of the sixth order. On the basis of the analytical decision of a problem the general and approached decisions of a problem are under construction, are deduced the equation of fluctuation of piecewise homogeneous two-layer plates taking into account rigid contact on border between layers, and also taking into account mechanical and rheological properties of a material of a plate. The received theoretical results for the decision of dynamic problems of cross-section fluctuation of piecewise homogeneous two-layer plates of a constant thickness taking into account viscous properties of their material allow to count more precisely the is intense-deformed status of plates at non-stationary external loadings.

Boundary element method in numerical study of three-dimensional Stokes flows in channels of arbitrary shape

2012 ◽  
Vol 9 (1) ◽  
pp. 94-97
Author(s):  
Yu.A. Itkulova
Keyword(s):  
Boundary Element Method ◽  
Boundary Element ◽  
Cross Section ◽  
Numerical Study ◽  
Three Dimensional ◽  
Cylindrical Tube ◽  
Variable Cross Section ◽  
Variable Cross ◽  
Periodic Flows ◽  
Element Method

In the present work creeping three-dimensional flows of a viscous liquid in a cylindrical tube and a channel of variable cross-section are studied. A qualitative triangulation of the surface of a cylindrical tube, a smoothed and experimental channel of a variable cross section is constructed. The problem is solved numerically using boundary element method in several modifications for a periodic and non-periodic flows. The obtained numerical results are compared with the analytical solution for the Poiseuille flow.

On the Influence of the Slot Orifice in Diesel Common Rail Nozzle

2018 ◽  
Vol 11 (1) ◽  
pp. 55-69 ◽  
Author(s):  
Giancarlo Chiatti ◽  
Ornella Chiavola ◽  
Fulvio Palmieri ◽  
Roberto Pompei
Keyword(s):  
Cross Section ◽  
Flow Rate ◽  
Experimental Analysis ◽  
Common Rail ◽  
Spray Angle ◽  
The Novel ◽  
Hydraulic Behavior ◽  
Reference Information ◽  
Light Duty ◽  
Set Up

Background:The paper deals with a diesel common rail nozzle in which a novel orifice layout is implemented.Objective:Its influence on the nozzle mechanical-hydraulic behavior and on the spray shape transient development is experimentally investigated.Methods:In the research, a solenoid injector for light duty diesel engines is equipped with the novel nozzle prototype and tested. The prototype layout is described, pointing out the features of the nozzle orifices, in which a Slot cross-section is adopted; the investigation is accomplished extending the hydraulic tests and the spray visualizations to a reference nozzle with standard holes. The influence of the hole layout on the mechanical-hydraulic behavior of the nozzle is assessed by experimental analysis based on the rate of injection measurement, in comparison with the reference nozzle. Once the hydraulic behavior of the novel nozzle has been characterized in terms of mass flow rate, the slot influence on the spray shape is assessed analyzing the macroscopic features such as the penetration distance and the spray angle, in non evaporative conditions. The study is carried out under transient injection conditions, for different injection pressures, up to 1400 bar.Results:The results on spray characteristics also provide reference information to set up spray models suited to take the Slot orifice into account.

scholarly journals Topological correlators and surface defects from equivariant cohomology

2020 ◽  
Vol 2020 (9) ◽  
Author(s):  
Rodolfo Panerai ◽  
Antonio Pittelli ◽  
Konstantina Polydorou
Keyword(s):  
Quantum Mechanics ◽  
Equivariant Cohomology ◽  
Surface Defects ◽  
Star Product ◽  
Three Dimensional ◽  
Three Dimensions ◽  
Dimensional System ◽  
The Novel ◽  
One Dimensional ◽  
Dual Quantum

Abstract We find a one-dimensional protected subsector of $$ \mathcal{N} $$ N = 4 matter theories on a general class of three-dimensional manifolds. By means of equivariant localization we identify a dual quantum mechanics computing BPS correlators of the original model in three dimensions. Specifically, applying the Atiyah-Bott-Berline-Vergne formula to the original action demonstrates that this localizes on a one-dimensional action with support on the fixed-point submanifold of suitable isometries. We first show that our approach reproduces previous results obtained on S3. Then, we apply it to the novel case of S2× S1 and show that the theory localizes on two noninteracting quantum mechanics with disjoint support. We prove that the BPS operators of such models are naturally associated with a noncom- mutative star product, while their correlation functions are essentially topological. Finally, we couple the three-dimensional theory to general $$ \mathcal{N} $$ N = (2, 2) surface defects and extend the localization computation to capture the full partition function and BPS correlators of the mixed-dimensional system.

Numerical and experimental investigation for enhancing the energy absorption capacity of the novel three-dimensional printed sandwich structures

2021 ◽  
pp. 146442072199749
Author(s):  
H Geramizadeh ◽  
S Dariushi ◽  
S Jedari Salami
Keyword(s):  
Energy Absorption ◽  
Sandwich Structures ◽  
Three Dimensional ◽  
Absorption Capacity ◽  
The Novel ◽  
Energy Absorption Capacity ◽  
Fused Deposition ◽  
Honeycomb Sandwich ◽  
Out Of Plane ◽  
Vertical Walls

The current study focuses on designing the optimal three-dimensional printed sandwich structures. The main goal is to improve the energy absorption capacity of the out-of-plane honeycomb sandwich beam. The novel Beta VI and Alpha VI were designed in order to achieve this aim. In the Beta VI, the connecting curves (splines) were used instead of the four diagonal walls, while the two vertical walls remained unchanged. The Alpha VI is a step forward on the Beta VI, which was promoted by filleting all angles among the vertical walls, created arcs, and face sheets. The two offered sandwich structures have not hitherto been provided in the literature. All models were designed and simulated by the CATIA and ABAQUS, respectively. The three-dimensional printer fabricated the samples by fused deposition modeling technique. The material properties were determined under tensile, compression, and three-point bending tests. The results are carried out by two methods based on experimental tests and finite element analyses that confirmed each other. The achievements provide novel insights into the determination of the adequate number of unit cells and demonstrate the energy absorption capacity of the Beta VI and Alpha VI are 23.7% and 53.9%, respectively, higher than the out-of-plane honeycomb sandwich structures.

scholarly journals Hydrothermal Synthesis and Structural Investigation of a Crystalline Uranyl Borosilicate

Inorganics ◽  
2021 ◽  
Vol 9 (4) ◽  
pp. 25
Author(s):  
Kristen A. Pace ◽  
Vladislav V. Klepov ◽  
Mark D. Smith ◽  
Travis Williams ◽  
Gregory Morrison ◽  
...  
Keyword(s):  
Synthesis Method ◽  
Three Dimensional ◽  
Dimensional Structure ◽  
Exploratory Research ◽  
The Novel ◽  
Orthorhombic Space Group ◽  
Crystalline Materials ◽  
Waste Remediation ◽  
And Storage ◽  
X Ray Absorption

The relevance of multidimensional and porous crystalline materials to nuclear waste remediation and storage applications has motivated exploratory research focused on materials discovery of compounds, such as actinide mixed-oxoanion phases, which exhibit rich structural chemistry. The novel phase K1.8Na1.2[(UO2)BSi4O12] has been synthesized using hydrothermal methods, representing the first example of a uranyl borosilicate. The three-dimensional structure crystallizes in the orthorhombic space group Cmce with lattice parameters a = 15.5471(19) Å, b = 14.3403(17) Å, c = 11.7315(15) Å, and V = 2615.5(6) Å3, and is composed of UO6 octahedra linked by [BSi4O12]5− chains to form a [(UO2)BSi4O12]3− framework. The synthesis method, structure, results of Raman, IR, and X-ray absorption spectroscopy, and thermal stability are discussed.

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