Cerebral Contour Extraction with Particle Method in Neonatal MR Images

Author(s):  
Syoji Kobashi ◽  
◽  
Daisuke Yokomichi ◽  
Yuki Wakata ◽  
Kumiko Ando ◽  
...  

Cerebral surface extraction from neonatal MR images is the basic work of quantifying the deformation of the cerebrum. Although there are many conventional methods of segmenting the cerebral region, only the rough area is given by counting the number of surface voxels in the segmented region. This article proposes a new method of extraction that is based on the particle method. The method introduces three kinds of particles that correspond to cerebrospinal fluid, gray matter, and white matter; it converts the brain MR images into the set of particles. The proposed method was applied to neonatal magnetic resonance images, and the experimental results showed that the cerebral contour was extracted with a root-mean-square-error of 0.51 mm compared with the ground truth contour given by a physician.

2020 ◽  
Vol 9 (1) ◽  
pp. 2425-2430

Brain imaging innovations have been forever made for a significant part in analyzing and focusing the unused sees of the brain life systems and functions. A computer software code is designed for the detection of cancer in brain magnetic resonance images. Image segmentation, morphological operations and feature extraction are some of the image processing methods developed for the brain cancer detection in MR images concerning the cancer influenced sufferers. In the proposed research, a Modified morphological-based Fuzzy-C-Means (MFCM) algorithm is proposed to segment the cancer region in the brain MR images. M-FCM algorithm is used to perform the segmentation process significantly through the idealize choice of a cluster, based on the updated membership function. Quantitative analysis between ground truth and segmented cancer is presented in terms of segmentation accuracy and segmentation sensitivity


Author(s):  
Pooja Prabhu ◽  
A. K. Karunakar ◽  
Sanjib Sinha ◽  
N. Mariyappa ◽  
G. K. Bhargava ◽  
...  

AbstractIn a general scenario, the brain images acquired from magnetic resonance imaging (MRI) may experience tilt, distorting brain MR images. The tilt experienced by the brain MR images may result in misalignment during image registration for medical applications. Manually correcting (or estimating) the tilt on a large scale is time-consuming, expensive, and needs brain anatomy expertise. Thus, there is a need for an automatic way of performing tilt correction in three orthogonal directions (X, Y, Z). The proposed work aims to correct the tilt automatically by measuring the pitch angle, yaw angle, and roll angle in X-axis, Z-axis, and Y-axis, respectively. For correction of the tilt around the Z-axis (pointing to the superior direction), image processing techniques, principal component analysis, and similarity measures are used. Also, for correction of the tilt around the X-axis (pointing to the right direction), morphological operations, and tilt correction around the Y-axis (pointing to the anterior direction), orthogonal regression is used. The proposed approach was applied to adjust the tilt observed in the T1- and T2-weighted MR images. The simulation study with the proposed algorithm yielded an error of 0.40 ± 0.09°, and it outperformed the other existing studies. The tilt angle (in degrees) obtained is ranged from 6.2 ± 3.94, 2.35 ± 2.61, and 5 ± 4.36 in X-, Z-, and Y-directions, respectively, by using the proposed algorithm. The proposed work corrects the tilt more accurately and robustly when compared with existing studies.


2016 ◽  
Vol 2016 ◽  
pp. 1-10
Author(s):  
Yunjie Chen ◽  
Tianming Zhan ◽  
Ji Zhang ◽  
Hongyuan Wang

We propose a novel segmentation method based on regional and nonlocal information to overcome the impact of image intensity inhomogeneities and noise in human brain magnetic resonance images. With the consideration of the spatial distribution of different tissues in brain images, our method does not need preestimation or precorrection procedures for intensity inhomogeneities and noise. A nonlocal information based Gaussian mixture model (NGMM) is proposed to reduce the effect of noise. To reduce the effect of intensity inhomogeneity, the multigrid nonlocal Gaussian mixture model (MNGMM) is proposed to segment brain MR images in each nonoverlapping multigrid generated by using a new multigrid generation method. Therefore the proposed model can simultaneously overcome the impact of noise and intensity inhomogeneity and automatically classify 2D and 3D MR data into tissues of white matter, gray matter, and cerebral spinal fluid. To maintain the statistical reliability and spatial continuity of the segmentation, a fusion strategy is adopted to integrate the clustering results from different grid. The experiments on synthetic and clinical brain MR images demonstrate the superior performance of the proposed model comparing with several state-of-the-art algorithms.


2020 ◽  
Vol 29 (1) ◽  
pp. 33-53
Author(s):  
Humera Azam ◽  
Humera Tariq

MRI scanner captures the skull along with the brain and the skull needs to be removed for enhanced reliability and validity of medical diagnostic practices. Skull Stripping from Brain MR Images is significantly a core area in medical applications. It is a complicated task to segment an image for skull stripping manually. It is not only time consuming but expensive as well. An automated skull stripping method with good efficiency and effectiveness is required. Currently, a number of skull stripping methods are used in practice. In this review paper, many soft-computing segmentation techniques have been discussed. The purpose of this research study is to review the existing literature to compare the existing traditional and modern methods used for skull stripping from Brain MR images along with their merits and demerits. The semi-systematic review of existing literature has been carried out using the meta-synthesis approach. Broadly, analyses are bifurcated into traditional and modern, i.e. soft-computing methods proposed, experimented with, or applied in practice for effective skull stripping. Popular databases with desired data of Brain MR Images have also been identified, categorized and discussed. Moreover, CPU and GPU based computer systems and their specifications used by different researchers for skull stripping have also been discussed. In the end, the research gap has been identified along with the proposed lead for future research work.


In this research, an automated and customized neoplasm segmentation methodology is given and valid against ground truth applying simulated T1-weighted resonance pictures in twenty five subjects. a replacement intensity-based segmentation technique known as bar graph primarily based gravitational optimization algorithm is developed to segment the brain image into discriminative sections (segments) with high accuracy. whereas the mathematical foundation of this rule is given in details, the appliance of the projected rule within the segmentation of single T1-weighted pictures (T1-w) modality of healthy and lesion MR images is additionally given. The results show that the neoplasm lesion is divided from the detected lesion slice with eighty nine.6% accuracy..


2021 ◽  
Vol 2021 ◽  
pp. 1-11
Author(s):  
Chuanqi Sun ◽  
Xiangyu Xiong ◽  
Tianjing Zhang ◽  
Xiuhong Guan ◽  
Huan Mao ◽  
...  

Objective. Deep vein thrombosis (DVT) is the third-largest cardiovascular disease, and accurate segmentation of venous thrombus from the black-blood magnetic resonance (MR) images can provide additional information for personalized DVT treatment planning. Therefore, a deep learning network is proposed to automatically segment venous thrombus with high accuracy and reliability. Methods. In order to train, test, and external test the developed network, total images of 110 subjects are obtained from three different centers with two different black-blood MR techniques (i.e., DANTE-SPACE and DANTE-FLASH). Two experienced radiologists manually contoured each venous thrombus, followed by reediting, to create the ground truth. 5-fold cross-validation strategy is applied for training and testing. The segmentation performance is measured on pixel and vessel segment levels. For the pixel level, the dice similarity coefficient (DSC), average Hausdorff distance (AHD), and absolute volume difference (AVD) of segmented thrombus are calculated. For the vessel segment level, the sensitivity (SE), specificity (SP), accuracy (ACC), and positive and negative predictive values (PPV and NPV) are used. Results. The proposed network generates segmentation results in good agreement with the ground truth. Based on the pixel level, the proposed network achieves excellent results on testing and the other two external testing sets, DSC are 0.76, 0.76, and 0.73, AHD (mm) are 4.11, 6.45, and 6.49, and AVD are 0.16, 0.18, and 0.22. On the vessel segment level, SE are 0.95, 0.93, and 0.81, SP are 0.97, 0.92, and 0.97, ACC are 0.96, 0.94, and 0.95, PPV are 0.97, 0.82, and 0.96, and NPV are 0.97, 0.96, and 0.94. Conclusions. The proposed deep learning network is effective and stable for fully automatic segmentation of venous thrombus on black blood MR images.


2013 ◽  
Author(s):  
Qaiser Mahmood ◽  
Mohammad Alipoor ◽  
Artur Chodorowski ◽  
Andrew Mehnert1 ◽  
Mikael Persson

In this paper, we validate our proposed segmentation algorithm called Bayesian-based adaptive mean-shift (BAMS) on real mul-timodal MR images provided by the MRBrainS challenge. BAMS is a fully automatic unsupervised segmentation algorithm. It is based on the adaptive mean shift wherein the adaptive bandwidth of the kernel for each feature point is estimated using our proposed Bayesian approach [1]. BAMS is designed to segment the brain into three tissues; white matter (WM), gray matter (GM) and cerebrospinal fluid (CSF). The performance of the algorithm is evaluated relative to the manual segmentation (ground truth). The results of our proposed algorithm show the average Dice index 0.8377±0.036 for the WM, 0.7637±0.038 for the GM and 0.6835 ±0.023 for the CSF.


2015 ◽  
Vol 2015 ◽  
pp. 1-14 ◽  
Author(s):  
Ketil Oppedal ◽  
Trygve Eftestøl ◽  
Kjersti Engan ◽  
Mona K. Beyer ◽  
Dag Aarsland

Dementia is an evolving challenge in society, and no disease-modifying treatment exists. Diagnosis can be demanding and MR imaging may aid as a noninvasive method to increase prediction accuracy. We explored the use of 2D local binary pattern (LBP) extracted from FLAIR and T1 MR images of the brain combined with a Random Forest classifier in an attempt to discern patients with Alzheimer's disease (AD), Lewy body dementia (LBD), and normal controls (NC). Analysis was conducted in areas with white matter lesions (WML) and all of white matter (WM). Results from 10-fold nested cross validation are reported as mean accuracy, precision, and recall with standard deviation in brackets. The best result we achieved was in the two-class problem NC versus AD + LBD with total accuracy of 0.98 (0.04). In the three-class problem AD versus LBD versus NC and the two-class problem AD versus LBD, we achieved 0.87 (0.08) and 0.74 (0.16), respectively. The performance using 3DT1 images was notably better than when using FLAIR images. The results from the WM region gave similar results as in the WML region. Our study demonstrates that LBP texture analysis in brain MR images can be successfully used for computer based dementia diagnosis.


2021 ◽  
Author(s):  
Zilong Zeng ◽  
Tengda Zhao ◽  
Lianglong Sun ◽  
Yihe Zhang ◽  
Mingrui Xia ◽  
...  

Precise segmentation of infant brain MR images into gray matter (GM), white matter (WM), and cerebrospinal fluid (CSF) is essential for studying neuroanatomical hallmarks of early brain development. However, for 6-month-old infants, the extremely low-intensity contrast caused by inherent myelination hinders accurate tissue segmentation. Existing convolutional neural networks (CNNs) based segmentation model for this task generally employ single-scale symmetric convolutions, which are inefficient for encoding the isointense tissue boundaries in limited samples of baby brain images. Here, we propose a 3D mixed-scale asymmetric convolutional segmentation network (3D-MASNet) framework for brain MR images of 6-month-old infant. We replaced the traditional convolutional layer of an existing to-be-trained network with a 3D mixed-scale convolution block consisting of asymmetric kernels (MixACB) during the training phase and then equivalently converted it into the original network. Five canonical CNN segmentation models were evaluated using both T1- and T2-weighted images of 23 6-month-old infants from iSeg-2019 datasets, which contained manual labels as ground truth. MixACB significantly enhanced the average accuracy of all five models and obtained the largest improvement in the fully convolutional network model (CC-3D-FCN) and the highest performance in the Dense U-Net model. This approach further obtained Dice coefficient accuracies of 0.931, 0.912, and 0.961 in GM, WM, and CSF, respectively, ranking first among 30 teams on the validation dataset of the iSeg-2019 Grand Challenge. Thus, the proposed 3D-MASNet can improve the accuracy of existing CNNs-based segmentation models as a plug-and-play solution that offers a promising technique for future infant brain MRI studies.


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