scholarly journals A novel sensing platform based on Polyglycine-Modified CVD Graphene for the Simultaneous Determination of Dopamine, Uric Acid, Guanine and Adenine

2020 ◽  
pp. 11387-11400
Author(s):  
Yitao Zhang ◽  
2014 ◽  
Vol 92 (11) ◽  
pp. 1074-1080 ◽  
Author(s):  
Majid Arvand ◽  
Mohsen Anvari

A simple and selective electrochemical method was investigated for the simultaneous determination of quercetin (Qu) and uric acid (UA) in aqueous media (citrate buffer solution, pH 4.0) on a glassy carbon electrode modified with graphene nanosheets as a sensing platform (GNSs/GCE). Cyclic voltammetry, transmission electron microscopy, and Fourier transform infrared spectroscopy were employed to characterize the nanostructure of the sensor. Separation of the oxidation peak potentials for Qu and UA was about 160 mV, and the anodic currents for the oxidation of both Qu and UA are greatly increased at GNSs/GCE, which makes it suitable for simultaneous determination of these compounds. The detection limits were 0.0011 and 0.0137 μmol/L for Qu and UA, respectively. The method was applied to the determination of Qu and UA in human blood serum and urine samples.


2017 ◽  
Vol 9 (47) ◽  
pp. 6689-6697 ◽  
Author(s):  
Danyu He ◽  
Shehong Li ◽  
Pu Zhang ◽  
Hongxia Luo

A novel electrochemical sensor based on a poly-l-cysteine/graphene platform was developed for the simultaneous determination of dopamine and ascorbic acid.


RSC Advances ◽  
2016 ◽  
Vol 6 (79) ◽  
pp. 75741-75748 ◽  
Author(s):  
S. Jesny ◽  
Shalini Menon ◽  
K. Girish Kumar

Simultaneous sensing of guanine and adenine in presence of uric acid in alkaline medium by polymer modified electrode.


2014 ◽  
Vol 2014 ◽  
pp. 1-10 ◽  
Author(s):  
Gen Liu ◽  
Wei Ma ◽  
Yan Luo ◽  
Deng-ming Sun ◽  
Shuang Shao

Poly(methylene blue) and electrochemically reduced graphene oxide composite film modified electrode (PMB-ERGO/GCE) was successfully fabricated by electropolymerization and was used for simultaneous determination of uric acid (UA) and xanthine (Xa). Based on the excellent electrocatalytic activity of PMB-ERGO/GCE, the electrochemical behaviors of UA and Xa were studied by cyclic voltammetry (CV) and square wave voltammetry (SWV). Two anodic sensitive peaks at 0.630 V (versus Ag/AgCl) for UA and 1.006 V (versus Ag/AgCl) for Xa were given by CV in pH 3.0 phosphate buffer. The calibration curves for UA and Xa were obtained in the range of 8.00 × 10−8~4.00 × 10−4 M and 1.00 × 10−7~4.00 × 10−4 M, respectively, by SWV. The detection limits for UA and Xa were3.00×10-8 M and5.00×10-8 M, respectively. Finally, the proposed method was applied to simultaneously determine UA and Xa in human urine with good selectivity and high sensitivity.


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