scholarly journals Calcium Phosphate-Chitosan Coatings Deposited on Titanium Surfaces via Pulse Galvanostatic Electrodeposition for Dental Implants

2020 ◽  
pp. 9611-9621
Author(s):  
Kyung Hee Park ◽  
Keyword(s):  
Calcium Phosphate ◽  
Dental Implants ◽  
Titanium Surfaces

scholarly journals Mineralization of Titanium Surfaces: Biomimetic Implants

Materials ◽  
2021 ◽  
Vol 14 (11) ◽  
pp. 2879
Author(s):  
Javier Gil ◽  
Jose Maria Manero ◽  
Elisa Ruperez ◽  
Eugenio Velasco-Ortega ◽  
Alvaro Jiménez-Guerra ◽  
...  
Keyword(s):  
Calcium Phosphate ◽  
Dental Implants ◽  
Early Stage ◽  
Calcium Phosphates ◽  
Biological Fixation ◽  
Biomimetic Surfaces ◽  
Titanium Surfaces ◽  
Deposition Processes ◽  
Fast Dissolution ◽  
Plasma Sprayed

The surface modification by the formation of apatitic compounds, such as hydroxyapatite, improves biological fixation implants at an early stage after implantation. The structure, which is identical to mineral content of human bone, has the potential to be osteoinductive and/or osteoconductive materials. These calcium phosphates provoke the action of the cell signals that interact with the surface after implantation in order to quickly regenerate bone in contact with dental implants with mineral coating. A new generation of calcium phosphate coatings applied on the titanium surfaces of dental implants using laser, plasma-sprayed, laser-ablation, or electrochemical deposition processes produces that response. However, these modifications produce failures and bad responses in long-term behavior. Calcium phosphates films result in heterogeneous degradation due to the lack of crystallinity of the phosphates with a fast dissolution; conversely, the film presents cracks, which produce fractures in the coating. New thermochemical treatments have been developed to obtain biomimetic surfaces with calcium phosphate compounds that overcome the aforementioned problems. Among them, the chemical modification using biomineralization treatments has been extended to other materials, including composites, bioceramics, biopolymers, peptides, organic molecules, and other metallic materials, showing the potential for growing a calcium phosphate layer under biomimetic conditions.

scholarly journals Proteome analysis of human serum proteins adsorbed onto different titanium surfaces used in dental implants

Biofouling ◽  
2016 ◽  
Vol 33 (1) ◽  
pp. 98-111 ◽  
Author(s):  
Francisco Romero-Gavilán ◽  
N. C. Gomes ◽  
Joaquin Ródenas ◽  
Ana Sánchez ◽  
Mikel Azkargorta ◽  
...  
Keyword(s):  
Human Serum ◽  
Dental Implants ◽  
Serum Proteins ◽  
Proteome Analysis ◽  
Titanium Surfaces ◽  
Human Serum Proteins

scholarly journals Bone Loss around Dental Implants 5 Years after Implantation of Biphasic Calcium Phosphate (HAp/βTCP) Granules

2018 ◽  
Vol 2018 ◽  
pp. 1-7 ◽  
Author(s):  
Vadims Klimecs ◽  
Alexanders Grishulonoks ◽  
Ilze Salma ◽  
Laura Neimane ◽  
Janis Locs ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Calcium Phosphate ◽  
Bone Loss ◽  
Dental Implants ◽  
Biphasic Calcium Phosphate ◽  
Alveolar Bone ◽  
Clinical Situation ◽  
Cone Beam ◽  
Calcium Phosphate Ceramic ◽  
Middle Point

Biphasic calcium phosphate ceramic granules (0.5–1.0 mm) with a hydroxyapatite and β-tricalcium phosphate ratio of 90/10 were used. Biphasic calcium phosphate ceramic granules produced in the Riga Technical University, Riga Rudolph Cimdins Biomaterials Innovation and Development Centre, were used for filling the bone loss on 18 patients with peri-implantitis. After 5 years at the minimum, clinical and 3D cone-beam computed tomography control was done. Clinical situation confirmed good stability of implants without any signs of inflammation around. Radiodensity of the previous gap and alveolar bone horizontally from middle point of dental implants showed similar radiodensity as in normal alveolar bone. This trial is registered with ISRCTN13514478.

scholarly journals Assessment of Dental Implants with Modified Calcium-Phosphate Surface in a Multicenter, Prospective, Non-Interventional Study: Results up to 50 Months of Follow-Up

2019 ◽  
Vol 10 (1) ◽  
pp. 5
Author(s):  
Carles Subirà-Pifarré ◽  
Cristina Masuet-Aumatell ◽  
Carlos Rodado Alonso ◽  
Ricardo Medina Madrid ◽  
Cosimo Galletti
Keyword(s):  
Clinical Practice ◽  
Survival Rate ◽  
Calcium Phosphate ◽  
Observational Study ◽  
Dental Implants ◽  
Daily Practice ◽  
High Rate ◽  
Osseointegrated Implants ◽  
Study Results

Prescription of implant treatments is very widespread at present, mainly due to the low rate of annual loss and, to date, few studies have assessed their survival in the routine clinical practice of dentistry. The purpose of this observational study was to evaluate the effectiveness of dental implants with a calcium-phosphate surface in the daily practice of dental clinics. A multicenter, prospective, non-interventional, observational study was performed, in which three experienced practitioners (one maxillofacial and two oral surgeons) inserted implants using standard external and internal hexagon connections in adult patients requiring ≥1 osseointegrated implants to replace missing teeth. Follow-up was performed for 24 months after implant loading. Two hundred and twelve subjects were included (51.5% men), with a mean age of 51.2 ± 11.90 years, in whom 544 implants were inserted. 87.2% of the patients received 1–4 implants. The preferred connection system was internal hexagon (73.5%). There were nine failures, with an interval survival rate (ISR) at 24 months of 100% and a cumulative survival rate (CSR) of 98.3%. In conclusion, implants with a modified calcium-phosphate surface are associated with a high rate of survival and may be considered a method of choice in clinical practice.

Electrochemical Deposition of Fluoridated Calcium Phosphate Thin Film on Titanium Substrates

2008 ◽  
Vol 47-50 ◽  
pp. 1387-1390 ◽  
Author(s):  
Xiang Ge ◽  
Fu Zeng Ren ◽  
Yang Leng
Keyword(s):  
Thin Film ◽  
Calcium Phosphate ◽  
Dental Implants ◽  
Titanium Substrate ◽  
Titanium Implants ◽  
Connective Tissues ◽  
Percutaneous Device ◽  
Fluorine Ions ◽  
Film Synthesis ◽  
Titanium Substrates

Percutaneous type of orthopedic and dental implants requires not only a good adhesion with bone, but also the ability to form good attachment and seal with connective tissues and skins. Currently, the skin-seal of such implants still remains as a problem to be resolved. Electrochemical processing was used to modify the surface of titanium implants in order to improve the ability of anti-bacteria infection and skin seal around the implants by synthesizing a fluoridated calcium phosphate thin film on titanium substrate. The surface of titanium was cathodically treated in an electrochemical cell. A thin film of about 80 nm thickness was deposited on the titanium surface by controlling the treatment parameters. The dense and gel-like film was composed of calcium phosphate and fluorine ions. Fluorine ion has the anti-bacteria property and could help to improve the skin seal around the percutaneous device. The electrochemical method of fluoridated calcium phosphate thin film synthesis will provide an alternative method for surface treatment of orthopedic and dental implants.

scholarly journals Covalently-Linked Hyaluronan versus Acid Etched Titanium Dental Implants: A Crossover RCT in Humans

2019 ◽  
Vol 20 (3) ◽  
pp. 763 ◽  
Author(s):  
Saturnino Lupi ◽  
Arianna Rodriguez y Baena ◽  
Clara Cassinelli ◽  
Giorgio Iviglia ◽  
Marco Tallarico ◽  
...  
Keyword(s):  
Bone Resorption ◽  
Dental Implants ◽  
Clinical Success ◽  
Molecular Layer ◽  
Host Responses ◽  
Biochemical Modification ◽  
Bone Level ◽  
Titanium Surfaces ◽  
Covalently Linked ◽  
Modification Of Titanium

Biochemical modification of titanium surfaces (BMTiS) entails immobilization of biomolecules to implant surfaces in order to induce specific host responses. This crossover randomized clinical trial assesses clinical success and marginal bone resorption of dental implants bearing a surface molecular layer of covalently-linked hyaluronan in comparison with control implants up to 36 months after loading. Patients requiring bilateral implant rehabilitation received hyaluronan covered implants in one side of the mouth and traditional implants in the other side. Two months after the first surgery, a second surgery was undergone to uncover the screw and to place a healing abutment. After two weeks, the operator proceeded with prosthetic procedures. Implants were evaluated by periapical radiographs and the crestal bone level was recorded at mesial and distal sites—at baseline and up to 36 months. One hundred and six implants were positioned, 52 HY-coated, and 48 controls were followed up. No differences were observed in terms of insertion and stability, wound healing, implant success, and crestal bone resorption at any time considered. All interventions had an optimal healing, and no adverse events were recorded. This trial shows, for the first time, a successful use in humans of biochemical-modified implants in routine clinical practice and in healthy patients and tissues with satisfactory outcomes.

scholarly journals Preparation of Bioactive Titanium Surfaces via Fluoride and Fibronectin Retention

2012 ◽  
Vol 2012 ◽  
pp. 1-7 ◽  
Author(s):  
Carlos Nelson Elias ◽  
Patricia Abdo Gravina ◽  
Costa e Silva Filho ◽  
Pedro Augusto de Paula Nascente
Keyword(s):  
Dental Implants ◽  
Dental Implant ◽  
Osteoblastic Cells ◽  
Acid Etching ◽  
Implant Surface ◽  
Force Microscopy ◽  
Dental Implant Surface ◽  
Before And After ◽  
Titanium Surfaces

Statement of Problem. The chemical or topographic modification of the dental implant surface can affect bone healing, promote accelerated osteogenesis, and increase bone-implant contact and bonding strength.Objective. In this work, the effects of dental implant surface treatment and fibronectin adsorption on the adhesion of osteoblasts were analyzed.Materials and Methods. Two titanium dental implants (Porous-acid etching and PorousNano-acid etching followed by fluoride ion modification) were characterized by high-resolution scanning electron microscopy, atomic force microscopy, and X-ray diffraction before and after the incorporation of human plasma fibronectin (FN). The objective was to investigate the biofunctionalization of these surfaces and examine their effects on the interaction with osteoblastic cells.Results. The evaluation techniques used showed that the Porous and PorousNano implants have similar microstructural characteristics. Spectrophotometry demonstrated similar levels of fibronectin adsorption on both surfaces (80%). The association indexes of osteoblastic cells in FN-treated samples were significantly higher than those in samples without FN. The radioactivity values associated with the same samples, expressed as counts per minute (cpm), suggested that FN incorporation is an important determinant of thein vitrocytocompatibility of the surfaces.Conclusion. The preparation of bioactive titanium surfaces via fluoride and FN retention proved to be a useful treatment to optimize and to accelerate the osseointegration process for dental implants.

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