scholarly journals Label-free Electrochemical Sensor for MicroRNA Detection based on a Gold Nanoparticles@Poly(methylene blue)-Modified Electrode and a Target Cyclic Amplification Strategy

Author(s):  
Weiwei Wang ◽  
2017 ◽  
Vol 9 (18) ◽  
pp. 2696-2702 ◽  
Author(s):  
Hoang Vinh Tran ◽  
Nghia Duc Nguyen ◽  
Benoit Piro ◽  
Luyen Thi Tran

In this work, we report a simple electrochemical method to fabricate a label-free and reagentless electrochemical sensor for microRNA detection based on self-assembly of a multifunctional layer on gold nanoparticles-modified glassy carbon electrodes (AuNPs/GCEs).


The Analyst ◽  
2021 ◽  
Vol 146 (8) ◽  
pp. 2679-2688
Author(s):  
Chammari Pothipor ◽  
Noppadol Aroonyadet ◽  
Suwussa Bamrungsap ◽  
Jaroon Jakmunee ◽  
Kontad Ounnunkad

An ultrasensitive electrochemical biosensor based on a gold nanoparticles/graphene/polypyrrole composite modified electrode and a signal amplification strategy employing methylene blue is developed as a potential tool for the detection of miRNA-21.


2019 ◽  
Vol 43 (48) ◽  
pp. 19003-19013 ◽  
Author(s):  
K. Krishna Kumar ◽  
M. Devendiran ◽  
R. A. Kalaivani ◽  
S. Sriman Narayanan

In the present study, a electrochemical sensor for the determination of dopamine was developed with green synthesised gold nanoparticles using curcumin as a reducing and, functionalizing agent.


Sensors ◽  
2021 ◽  
Vol 21 (8) ◽  
pp. 2850
Author(s):  
Fairouz Aberkane ◽  
Imene Abdou ◽  
Nadia Zine ◽  
Nicole Jaffrezic-Renault ◽  
Abdelhamid Elaissari ◽  
...  

Melamine has been used as a non-protein nitrogenous additive in food products to artificially increase the apparent “false” protein content. Melamine is known as a dangerous and poisonous substance for human health and it causes diverse diseases. An electrochemical sensor for melamine detection has been developed by modification of a glassy carbon electrode using copolymer poly[DMAEMA-co-styrene], gold nanoparticles, and methylene blue. The characterization of the modified electrode was conducted using several analysis techniques including cyclic voltammetry (CV), differential pulse voltammetry (DPV), chronoamperometry (CA), and electrochemical impedance spectroscopy (EIS). The electrochemical detection of melamine was performed by impedance spectroscopy. Obtained results revealed that the developed sensor has a large detection range from 5.0 × 10−13 to 3.8 × 10−8 M with a low detection limit of 1.8 × 10−12 M (at S/N = 3). Various interfering species such as phenol, hydroquinone, and bisphenol A have been used and their behavior on modified electrode has been studied.


RSC Advances ◽  
2020 ◽  
Vol 10 (63) ◽  
pp. 38316-38322
Author(s):  
Jing Lin ◽  
Kunyin Li ◽  
Meifang Wang ◽  
Xiaohong Chen ◽  
Jiyang Liu ◽  
...  

A label-free electrochemical sensor is easily fabricated based on stable and surface-confined Prussian blue for reagentless and sensitive detection of carcinoembryonic antigen.


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