scholarly journals Electrochemical Sensor for Detection of Ascorbic Acid Using a Methylene Blue-Doped Polyimide-Modified Glassy Carbon Electrode

2019 ◽  
pp. 8494-8505
Author(s):  
Tian Yang ◽  
Keyword(s):  
Methylene Blue ◽  
Ascorbic Acid ◽  
Electrochemical Sensor ◽  
Glassy Carbon Electrode ◽  
Glassy Carbon ◽  
Carbon Electrode ◽  
Modified Glassy Carbon Electrode

Sensitive Detection of Levocetirizine as a new Generation Antihistamine by Stripping Square Wave Voltammetry

2020 ◽  
Vol 16 (4) ◽  
pp. 424-437
Author(s):  
Kubra Ozturk ◽  
Nurgul K. Bakirhan ◽  
Sibel A. Ozkan ◽  
Bengi Uslu
Keyword(s):  
Electrochemical Sensor ◽  
Glassy Carbon Electrode ◽  
Glassy Carbon ◽  
Differential Pulse ◽  
Real Sample ◽  
Carbon Electrode ◽  
Modified Glassy Carbon Electrode ◽  
Square Wave ◽  
Real Sample Analysis ◽  
Tablet Dosage

Background:: new and selective electrochemical sensor was developed for the determination of levocetirizine dihydrochloride, which is an antihistaminic drug. Method:: The investigation was performed by using cyclic, differential pulse and square wave voltammetric methods on the β-cyclodextrin modified glassy carbon electrode. It is thereby planned to obtain information about levocetirizine determination and its mechanism. Result:: The efficiency of experimental parameters including pH, scan rate, and accumulation potential and time on the anodic response of levocetirizine dihydrochloride was studied. By employing the developed method and under optimized conditions, the current showed linear dependence with a concentration in the range between 2 × 10-8 M and 6 × 10-6 M in pH 2.0 Britton Robinson (BR) buffer. Conclusion:: The achieved limits of detection and quantification were found as 3.73 × 10-10 M and 1.24 × 10-9 M, respectively. In addition, the possibility of applying the developed sensor for real sample analysis was investigated, so β-cyclodextrin modified glassy carbon electrode was used to determine levocetirizine dihydrochloride in Xyzal® tablet dosage form. Finally, this sensor was successfully applied to the real sample as a selective, simple, reproducible, repeatable electrochemical sensor.

Highly sensitive detection of hesperidin using AuNPs/rGO modified glassy carbon electrode

The Analyst ◽  
2018 ◽  
Vol 143 (1) ◽  
pp. 297-303 ◽  
Author(s):  
Yang Gao ◽  
Xiufeng Wu ◽  
Hui Wang ◽  
Wenbo Lu ◽  
Mandong Guo
Keyword(s):  
Gold Nanoparticles ◽  
Graphene Oxide ◽  
Electrochemical Sensor ◽  
Glassy Carbon Electrode ◽  
Glassy Carbon ◽  
Carbon Electrode ◽  
Modified Glassy Carbon Electrode ◽  
Reduced Graphene ◽  
Highly Sensitive ◽  
Highly Sensitive Detection

The highly sensitive and selective electrochemical sensor of hesperidin based on gold nanoparticles (AuNPs) and reduced graphene oxide (rGO) modified glassy carbon electrode (GCE) is reported.

scholarly journals Electrochemical antioxidant screening and evaluation based on guanine and chitosan immobilized MoS2 nanosheet modified glassy carbon electrode (guanine/CS/MoS2/GCE)

2020 ◽  
Vol 18 (1) ◽  
pp. 1-9 ◽  
Author(s):  
Ping Tang ◽  
Xiaosheng Tang ◽  
Shiyong Mei ◽  
Yixi Xie ◽  
Liangliang Liu ◽  
...  
Keyword(s):  
Ascorbic Acid ◽  
Antioxidant Capacity ◽  
Glassy Carbon Electrode ◽  
Glassy Carbon ◽  
Carbon Electrode ◽  
Oxidation Peak ◽  
Modified Glassy Carbon Electrode ◽  
Peak Current ◽  
Oxidation Peak Current ◽  
Antioxidant Capacities

AbstractIn this study, an electrochemical biosensor based on guanine and chitosan immobilized MoS2 nanosheet modified glassy carbon electrode (guanine/CS/MoS2/GCE) was developed and employed for antioxidant screening and antioxidant capacity evaluation. The oxidation peak current of guanine was improved and nearly tripled after modifications of chitosan and MoS2 nanosheet. The immobilized guanine could be damaged by hydroxyl radicals generated in Fenton solution. However, in the presence of antioxidants, the guanine was protected and the oxidation peak current of guanine increased. This process mimics the mechanism of antioxidant protection in human body. The factors affecting preparation of sensor and detection of antioxidant capacity were optimized. At the optimum conditions, the guanine/CS/MoS2/GCE showed wide linear range, low detection limit, satisfactory reproducibility and stability for detection. Ascorbic acid was used as a model antioxidant to evaluate the antioxidant capacity. A good linearity was observed with a correlation coefficient of 0.9959 in the concentrations between 0.5 and 4.0 mg L-1. The antioxidant capacities of three flavonoids were also tested and the rank of antioxidant capacities was ascorbic acid (51.84%), quercetin (45.82%), fisetin (34.39%) and catechin (16.99%). Due to the rapid measurement and low cost, this sensor could provide an available sensing platform for antioxidant screening and evaluation.

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