scholarly journals Clinical symptoms are correlated with gastrojejunal anastomosis complications only during the first year after laparoscopic Roux-en-Y gastric bypass

2021 ◽  
Author(s):  
Norberto Cassinello Fernández ◽  
María Lapeña Rodríguez ◽  
José Martín Arévalo ◽  
Vicente Sanchíz Soler ◽  
Raquel Alfonso Ballester ◽  
...  
Author(s):  
Fernando Munoz-Flores ◽  
Jorge Humberto Rodriguez-Quintero ◽  
David Pechman ◽  
Collin Creange ◽  
Ariela Zenilman ◽  
...  

Author(s):  
Songul Gokay ◽  
Pembe Soylu Ustkoyuncu ◽  
Fatih Kardas ◽  
Mustafa Kendirci

AbstractBackground:Hereditary tyrosinemia type 1 (HT1) is a rare, inborn error of tyrosine metabolism. It is a fatal disorder without treatment. Early treatment may prevent acute liver failure, renal dysfunction, liver cirrhosis, hepatocellular carcinoma (HCC) and improves survival. The aim of the present study is to describe the clinical, biochemical, imaging and follow-up of seven patients with HT1 and to define the consequences of the late and interrupted treatment.Methods:A retrospective study was carried out with seven HT1 patients.Results:The median age at onset of clinical symptoms was 11.2 months (range, 3–28 months) and the median age at diagnosis was 22 months (range, 6–58 months). Liver enzymes and coagulation parameters were back to normal in all symptomatic patients in about 2 weeks. Alfa-fetoprotein (AFP) levels were normalized within the first year of therapy. Hypoechoic nodule formation was detected in two of the seven patients despite drug treatment without an increase of AFP and any dysplastic changes in the biopsies. One patient died due to metastatic HCC because of the late diagnosis and the poor compliance of the follow-up.Conclusions:This study showed once again that adherence to the treatment and a follow-up schedule of the patients are very important. Also it should not be forgotten that nodule formation can occur despite nitisinone treatment without an increase of AFP. Despite nitisinone treatment, HT1 patients still carry the risk of HCC. HCC must be detected before metastasis to other organs otherwise, patients may lose the chance for liver transplantation.


2018 ◽  
Vol 12 (2) ◽  
pp. 76-79
Author(s):  
V. S. Samoylov ◽  
V. V. Novomlinskiy ◽  
N. А. Malkina

The number of post-bariatric patients is increasing from year to year; any medical specialist can see consequences and sometimes complications of these interventions. The variety of different scenarios associated with such patients is not well studied. Mini-gastric bypass (MGB-OAGB) is a major type of primary or recurrent bariatric surgery in obese patients. Biliary reflux (BR) is one of the most significant late complications of this operation. An increase in the intra-abdominal pressure during pregnancy can lead to the development of BR with its typical clinical symptoms, which may sometimes puzzle an obstetrician-gynecologist. In these cases, there are limitations in using traditional diagnostic approaches and regular medications for conservative treatment of BR. This report presents a clinical observation on a patient who underwent MGB-OAGB as a recurrent bariatric intervention for her morbid obesity. With no signs of gastroesophageal reflux before surgery, soon after it or in the I trimester of pregnancy, a typical clinical picture of BR developed in the II and III trimesters. A complete relief of the BR symptoms after the childbirth (confirmed by gastro-esophago-scopy) suggested a direct connection between the BR and the increase in intra-abdominal pressure during pregnancy.


1987 ◽  
Vol 15 (3) ◽  
pp. 227-233 ◽  
Author(s):  
Harry L. Piersma

During the past several decades, many studies have examined the emotional and psychological functioning of clergy and seminarians. In most instances, researchers employed separate measures to study general personality characteristics as contrasted with psychopathologic factors. In this study, the Millon Clinical Multiaxial Inventory (MCMI) was administered to 52 first-year male seminarians at Calvin Theological Seminary in Grand Rapids, Michigan. The MCMI is designed to measure relatively fixed personality characteristics in addition to more psychopathologic factors. As expected, seminarians evidenced little psychopathology on scales designed to assess clinical symptoms. On the basic personality scales, results indicated that the typical seminarian profile would be most consistent with the “conforming” personality described by Millon (1981). Suggestions for further research are discussed.


2016 ◽  
Vol 12 (7) ◽  
pp. S15-S16
Author(s):  
Zach Ichter ◽  
Lindsey Voller ◽  
Ovet Esparza ◽  
Dan Azagury ◽  
Homero Rivas ◽  
...  

2010 ◽  
Vol 25 (2) ◽  
pp. 597-603 ◽  
Author(s):  
Gitana Scozzari ◽  
Fabrizio Rebecchi ◽  
Paolo Millo ◽  
Stefano Rocchietto ◽  
Rosaldo Allieta ◽  
...  

1977 ◽  
Author(s):  
J.J. Veltkamp

In newborns the factor IX level is only 20-60% of that observed in adults. This implies that factor IX levels have to increase with age, as was demonstrated already by Simpson and Biggs (1962). A rapid rise might occur in the first year of life, as is the case for albumen. During life, then, a slow rise continues, as was also demonstrated for factors V and VII (Brozovic 1976, 1974). It is of special interest that for factors VII and IX, both vitamin K dependant clotting factors, not onlyage but also hormones influence the activity level. Both the oestrogen containing contraceptive pill and pregnancy cause a substantial rise in factor IX level, both activity and CRM. 7 Years ago we started to measure factor IX levels every 3 months in 10 children, now at the age of 19, to see whether an abrupt rise would occur during puberty; this was not so. This information was considered relevant for the explanation of the appearance of factor IX activity and CRM in patients with hemophilia B Leyden during puberty. After a rise from <1% to 20% factor IX in the age period from 15 to 20 factor IX continues to rise at a slower rate and may reach 50% in old age. Clinical symptoms disappear. There is no good explanation for this phenomenon that occurs in patients from two probably related kindreds with hemophilia B in The Netherlands.


2012 ◽  
Vol 142 (5) ◽  
pp. S-179
Author(s):  
Nitin Kumar ◽  
Marvin Ryou ◽  
Barham K. Abu Dayyeh ◽  
Pichamol Jirapinyo ◽  
David B. Lautz ◽  
...  

2012 ◽  
Vol 23 (1) ◽  
pp. 140-144 ◽  
Author(s):  
José Ignacio Fernández ◽  
Cristian Ovalle ◽  
Carlos Farias ◽  
Jaime de la Maza ◽  
Carolina Cabrera

2012 ◽  
Vol 2012 ◽  
pp. 1-7 ◽  
Author(s):  
E. O. Aarts ◽  
B. van Wageningen ◽  
I. M. C. Janssen ◽  
F. J. Berends

Background. Anemia associated with deficiencies in iron, folic acid, and vitamin B12 are very common after Laparoscopic Roux-en-Y Gastric Bypass (LRYGB) surgery for morbid obesity. This study was conducted to evaluate the prevalence of anemia after LRYGB.Patients and Methods. A total of 377 morbid obese patients were included in our study. All patients underwent a LRYGB. Hematologic parameters were obtained prior to and after surgery on standardized time intervals.Results. Anemia was present in 21 (P=0.02) patients after surgery. Iron, folic acid, and vitamin B12 deficiencies were diagnosed in 66%, 15%, and 50% of patients, respectively. In 86% of patients, anemia was accompanied by one of these deficiencies.Conclusion. These results show that anemia and deficiencies for iron, folic acid deficiency, and vitamin B12 are very common within the first year after LRYGB. We advise a minimal daily intake of 65 mg of iron in male and 100 mg in female patients, 350 μg of vitamin B12, and 400 μg of folic acid. Patients undergoing LRYGB must be closely monitored for deficiencies pre- and postoperative and supplemented when deficiencies occur.


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