PHYTOCHEMICAL ANALYSIS AND IN VITRO ANTICANCER STUDY OF ETHANOLIC EXTRACT OF LEAVES OF AMARANTHUS CRUENTUS LINN. AGAINST COLON CANCER CELL LINE (HCT-116)

2017 ◽  
pp. 1644-1658 ◽  
Author(s):  
Vithya Sekar
Keyword(s):  
Colon Cancer ◽  
Cell Line ◽  
Cancer Cell Line ◽  
Ethanolic Extract ◽  
Colon Cancer Cell Line ◽  
Colon Cancer Cell ◽  
Phytochemical Analysis ◽  
Amaranthus Cruentus ◽  
Hct 116

scholarly journals Ethanolic extract ofBrucea javanicainhibit proliferation of HCT-116 colon cancer cellsviacaspase activation

RSC Advances ◽  
2018 ◽  
Vol 8 (2) ◽  
pp. 681-689 ◽  
Author(s):  
E. Bagheri ◽  
F. Hajiaghaalipour ◽  
S. Nyamathulla ◽  
N. A. Salehen
Keyword(s):  
Colon Cancer ◽  
Cell Line ◽  
Cancer Cell Line ◽  
Ethanolic Extract ◽  
Colon Cancer Cell Line ◽  
Colon Cancer Cell ◽  
Brucea Javanica ◽  
Ethanolic Extracts ◽  
Hct 116 ◽  
Induced Apoptosis

Brucea javanicaethanolic extracts induced apoptosis in colon cancer cell line (HCT-116)viamitochonderial and extrinsic pathways.

In vitro antitumour activity of two ferrocenyl metallodendrimers in a colon cancer cell line

2018 ◽  
Vol 98 ◽  
pp. 75-79 ◽  
Author(s):  
Nadia Baartzes ◽  
Cristina Szabo ◽  
Mihai Cenariu ◽  
Florica Imre-Lucaci ◽  
Sorin Aurel Dorneanu ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Cell Line ◽  
Cancer Cell ◽  
Antitumour Activity ◽  
Cancer Cell Line ◽  
Colon Cancer Cell Line ◽  
Colon Cancer Cell

scholarly journals Phytochemical analysis and cytotoxic activities of two distinct cultivars of Ganyong rhizomes (Canna indica) against the WiDr colon cancer cell line

2020 ◽  
Vol 21 (4) ◽  
Author(s):  
IFANDARI ◽  
SITARINA WIDYARINI ◽  
L. HARTANTO NUGROHO ◽  
Rarastoeti Pratiwi
Keyword(s):  
Colon Cancer ◽  
Cell Viability ◽  
Cell Line ◽  
Functional Group ◽  
Cancer Cell Line ◽  
Colon Cancer Cell Line ◽  
Colon Cancer Cell ◽  
Cytotoxic Activities ◽  
Phytochemical Analysis ◽  
Canna Indica

Abstract. Ifandari, Widyarini S, Nugroho LH, Pratiwi R. 2020. Phytochemical analysis and cytotoxic activities of two distinct cultivars of Ganyong rhizomes (Canna indica) against the WiDr colon cancer cell line. Biodiversitas 21: 1660-1669. Canna indica L is an edible plant with high nutrient content and positive health benefits. In Indonesia, edible canna is divided into two cultivar groups: red edible canna and green edible canna. Canna indica L. is investigated in this study as a potential medicinal plant for colon cancer in WiDr cell lines. The phytochemical contents of two distinct cultivars of edible canna (known in Indonesia as ganyong), namely red edible canna and green edible canna. These two discrete samples were extracted by using two different solvents, dichloromethane and ethanol, followed by evaluation using Fourier-transform infrared (FTIR) spectroscopy in order to detected functional group. In the analysis of the composition of the elements of chemical compounds, the samples subsequently injected into the liquid chromatography−high-resolution mass spectrometry (LC-HRMS). The cell viability assay was performed to evaluate the cytotoxic activities of extracted compounds from two cultivars of edible canna in two different solvents. FTIR results demonstrated that the red and green edible canna extracts contained 17 and 18 functional group compounds, respectively. Furthermore, the cell viability was lower in WiDr cells treated with dichloromethane extract of red than green edible canna or the ethanol extract of red edible canna. Notably, LC-HRMS results of the most potent dichloromethane extract of red edible canna revealed the presence of fatty acid compounds. These findings indicate that the two cultivars of edible canna could potentially be utilized as promising candidates for colon cancer treatment.

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