scholarly journals Preoperatively undiagnosed papillary thyroid carcinoma in patients thyroidectomized for benign multinodular goiter

2018 ◽  
Author(s):  
Fausto Fama ◽  
Alessandro Sindoni ◽  
Marco Cicciu ◽  
Francesca Polito ◽  
Arnaud Piquard ◽  
...  
Keyword(s):  
Papillary Thyroid Carcinoma ◽  
Thyroid Carcinoma ◽  
Multinodular Goiter ◽  
Papillary Thyroid

scholarly journals Synchronous Thyrolipoma and Papillary Thyroid Carcinoma: A Rare but Significant Event

Diagnostics ◽  
2021 ◽  
Vol 11 (8) ◽  
pp. 1334
Author(s):  
Mariya Kuk ◽  
Chu-Jen Kuo ◽  
Van-Hung Nguyen ◽  
Chien-Chin Chen
Keyword(s):  
Papillary Thyroid Carcinoma ◽  
Thyroid Carcinoma ◽  
Multinodular Goiter ◽  
Incidental Finding ◽  
Papillary Thyroid ◽  
Solitary Lesion ◽  
Neck Lymph Node ◽  
Thyroid Carcinomas ◽  
Right Lobe ◽  
The Right

The presence of adipocytes within thyroid glands is a rare finding seen in thyrolipoma, diffuse lipomatosis, or thyroid teratoma. Although some cases present with multinodular goiter or autoimmune thyroiditis, the exact cause has not yet been elucidated. Among reported cases, thyrolipomas mainly occur in females and usually present as a solitary lesion. However, a few reported cases had coexisting papillary thyroid carcinomas. Herein, we present a 51-year-old female with synchronous thyrolipoma (2.0 × 1.5 × 1.3 cm) and papillary thyroid carcinoma (0.7 × 0.6 × 0.6 cm) within the same thyroid lobe. She had diabetes mellitus and hypertension and complained of anterior neck enlargement and discomfort for three months. Thyroid sonography showed multiple hypoechoic nodules, one of which was heterogeneous and ill-defined. Fine needle aspirate cytology for the ill-defined nodule was suspicious for papillary thyroid carcinoma. She subsequently received radical thyroidectomy and neck lymph node dissection. Histopathologically, one thyrolipoma and one papillary thyroid carcinoma were identified in the right lobe of the thyroid gland without metastases of lymph nodes, while other nodules were multinodular goiter. Notably, thyrolipoma may not be simply an incidental finding but might coexist with thyroid carcinomas. A brief review of the pertinent literature of prior reports is also provided.

scholarly journals Evaluation of thyroid nodules classified as Bethesda category III on cytology and their malignancy rate: An institutional experience

CytoJournal ◽  
2019 ◽  
Vol 16 ◽  
pp. 18 ◽  
Author(s):  
Sayed Ali Almahari ◽  
Zainab Harb ◽  
Safa Alshaikh
Keyword(s):  
Papillary Thyroid Carcinoma ◽  
Thyroid Carcinoma ◽  
Multinodular Goiter ◽  
Thyroid Nodules ◽  
Follicular Adenoma ◽  
Hashimoto Thyroiditis ◽  
International Standards ◽  
Papillary Thyroid ◽  
Institutional Experience ◽  
Undetermined Significance

Background: Thyroid gland nodules are common and fine-needle aspiration (FNA) is the gold standard for screening those nodules. The Bethesda system for reporting thyroid cytolopathology standardized reporting thyroid nodules aspirations, but atypia of undetermined significance or follicular lesion of undetermined significance (Bethesda category III) was the most controversial category. The aim of our study is to review our institutional experience and analyze the clinical implications of making a diagnosis of AUS/FLUS (Bethesda category III). Methods: This is a retrospective study of an 889 thyroid FNAs from 825 patients in Salmaniya Medical Complex, during (January 2013–December 2017). Results: The most common cause for designating cases as AUS/FLUS (Bethesda category III) was the presence of features suggestive of papillary thyroid carcinoma, but not quite fulfilling the criteria for such diagnosis. Ninety-six cases were diagnosed as AUS/FLUS (10.7%), in which 26 (27%) patients underwent surgery without repeating the FNA, 25 (26%) underwent a second FNA and 43 (44.7%) patients were followed up by ultrasound. On repeating the FNA, 1 (4%) was unsatisfactory, 13 (52%) were benign, 10 (40%) were AUS/FLUS, and only 1 (4%) was categorized as malignant. Thirty cases were surgically excised, in which 4 (13.3%) were diagnosed as follicular adenoma, 2 (6.6%) as Hurthle cell adenoma, 9 (30%) as multinodular goiter, 5 (16.6%) as multinodular goiter with Hashimoto thyroiditis, 1 (3.3%) as colloid nodule with Hashimoto thyroiditis, and 9 (30%) as papillary thyroid carcinoma. Among all the cases diagnosed initially as AUS/FLUS (Bethesda category III), 9 (9.3%) cases were diagnosed as papillary thyroid carcinoma. Conclusion: Diagnostically, we almost meet the international standards of designating cases with AUS/FLUS (Bethesda category III) and approximate the risk of malignancy. However, the clinical management's guidelines should be followed to decrease the risk of unnecessary surgeries and their complications. There is a statistically significant correlation between the age and gender with the final histopathology report, respectively.

Estrogen Receptor (ER)-β, But Not ER-α, Is Present in Thyroid Vessels: Immunohistochemical Evaluations in Multinodular Goiter and Papillary Thyroid Carcinoma

Thyroid ◽  
2006 ◽  
Vol 16 (12) ◽  
pp. 1215-1220 ◽  
Author(s):  
Graziano Ceresini ◽  
Simonetta Morganti ◽  
Virna Graiani ◽  
Maria Saccani ◽  
Bruna Milli ◽  
...  
Keyword(s):  
Estrogen Receptor ◽  
Papillary Thyroid Carcinoma ◽  
Thyroid Carcinoma ◽  
Multinodular Goiter ◽  
Papillary Thyroid

The evaluation of serum micro and trace elements in patients with papillary thyroid carcinoma and multinodular goiter

2019 ◽  
Vol 36 (10) ◽  
pp. 215-221
Author(s):  
Reyhaneh Farrokhi Yekta ◽  
Afsaneh Arefi Oskouie ◽  
Salman Taheri ◽  
Hesam Daneshyar
Keyword(s):  
Trace Elements ◽  
Papillary Thyroid Carcinoma ◽  
Thyroid Carcinoma ◽  
Multinodular Goiter ◽  
Papillary Thyroid
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