scholarly journals Synthesis, Characterization and Antimicrobial Studies of SnO2 Nanoparticles

2020 ◽  
Vol 13 (3) ◽  
pp. 203-209
Author(s):  
Sumathi . P
Keyword(s):  
Antibacterial Activity ◽  
Sno2 Nanoparticles ◽  
Antimicrobial Properties ◽  
Cost Effective ◽  
Salmonella Typhi ◽  
Gram Positive Bacteria ◽  
Antimicrobial Studies ◽  
Sno2 Nanoparticle ◽  
Bacteria And Fungi ◽  
Antibacterial And Antifungal

This study was involved to synthesize and investigate the antimicrobial properties of highly pure nanocrystalline SnO2 by simple chemical method. In the nanorods, SnO2 nanoparticles, with a size of about 74 nm, the SnO2 nanoparticles were maximum antibacterial activity against both bacterial and fungal with the zone of inhibition for Klebsiella pneumoniae, Staphylococcus aures, Salmonella typhi and Ascerpergillus Flavus, Ascerpergillus Niger from 25μg/ml and 100 μg/ml respectively. SnO2 nanoparticles showed good activity against both Gram-negative and Gram-positive bacteria confirming these as future broad spectrum antibacterial a cost effective way and to study its antimicrobial properties. We observed an effective antibacterial and antifungal activity of the SnO2 nanoparticle against bacteria and fungi. The results showed that SnO2 nanoparticles enhanced the good antibacterial activity.

scholarly journals Synthesis, Antibacterial and Antifungal Properties of Cyclohexane Tosyloxyimine Derivative

2019 ◽  
Vol 4 (3) ◽  
pp. 1-4
Author(s):  
Shoaib M
Keyword(s):  
Antimicrobial Agents ◽  
Sulfonyl Chloride ◽  
Antimicrobial Properties ◽  
Gram Positive ◽  
Gram Negative ◽  
Gram Positive Bacteria ◽  
Bacteria And Fungi ◽  
Agar Well Diffusion Assay ◽  
Antibacterial And Antifungal ◽  
Candida Pseudotropicalis

Due to increasing antimicrobial resistance, functionally substituted cyclohexane derivatives are being explored as potential antimicrobial agents. Reaction of diethyl 4 - hydroxy - 6 - (hyd - roxyimino) - 4 - methyl - 2 - phenylcyclohexane - 1,3 - dicarboxylate with 4 - toluene sulfonyl chloride in boiling acetone in the presence of equimolar triethylamine resulted in formation of diethyl - 4 - hydroxy - 4 - methyl - 2 - phenyl - 6 - ((tosyloxy)imino) cyclohexane - 1,3 - dicarboxylate. The structure of novel compound was characterized by 1 H and 13 C NMR spectra and elemental analysis was performed. Agar well diffusion assay was used to screen novel compound against Gram - positive bacteria, Gram - negative bacteria and fungi. Test compound showed better antimicrobial properties against Gram - negative bac teria as compared to Gram - positive bacteria and fungi. Acinetobacter baumannii BDU - 32 was found to be most sensitive bacteria while Candida pseudotropicalis BDU MA88 was found to be most sensitive yeast.

scholarly journals Antibacterial activity of Baccharis trimera (Less.) DC. (carqueja) against bacteria of medical interest

Revista CERES ◽  
2013 ◽  
Vol 60 (5) ◽  
pp. 731-734 ◽  
Author(s):  
Álan Alex Aleixo ◽  
Karina Marjorie Silva Herrera ◽  
Rosy Iara Maciel de Azambuja Ribeiro ◽  
Luciana Alves Rodrigues dos Santos Lima ◽  
Jaqueline Maria Siqueira Ferreira
Keyword(s):  
Antibacterial Activity ◽  
Folk Medicine ◽  
Salmonella Typhi ◽  
Bacterial Strains ◽  
Gram Positive ◽  
Gram Positive Bacteria ◽  
Clinical Interest ◽  
Antibacterial Susceptibility ◽  
Baccharis Trimera ◽  
Medical Interest

Baccharis trimera (Less.) (Asteraceae), popularly know as "carqueja", is a species commonly used in folk medicine for the treatment or prevention of diseases. In this context, the purpose of this work was to study the antibacterial activity of crude hydroalcoholic extract from Baccharis trimera against Gram-positive bacterial strains (Staphylococcus aureus ATCC 29213, Staphylococcus saprophyticus ATCC 15305, Staphylococcus epidermidis ATCC 12228, Enterococcus faecalis ATCC 19433) and Gram-negative bacteria (Escherichia coli EHEC ATCC 43895, Pseudomonas aeruginosa ATCC 27853, Klebsiella pneumoniae ATCC 27736, Salmonella typhi ATCC 19430) of clinical interest. Antibacterial susceptibility was evaluated by broth microdilution assay following the CLSI (formerly the NCCLS) guidelines. The extract from B. trimera showed antibacterial activity against Gram-positive bacteria and the most interesting result was obtained against S. epidermidis that presented Minimal Inhibitory Concentration of 250μg/mL. These results indicate that B. trimera have bacterisostatic potential against Gram-positive bacterial strains of medical interest and could serve as a base for further studies on the use of isolated compounds from this species as future antimicrobials.

scholarly journals Chemical Composition, Antimicrobial Properties of Siparuna guianensis Essential Oil and a Molecular Docking and Dynamics Molecular Study of its Major Chemical Constituent

Molecules ◽  
2020 ◽  
Vol 25 (17) ◽  
pp. 3852
Author(s):  
Mozaniel Santana de Oliveira ◽  
Jorddy Neves da Cruz ◽  
Wanessa Almeida da Costa ◽  
Sebastião Gomes Silva ◽  
Mileide da Paz Brito ◽  
...  
Keyword(s):  
Molecular Dynamics ◽  
Essential Oil ◽  
Antimicrobial Properties ◽  
Molecular Study ◽  
Chemical Constituent ◽  
Target Proteins ◽  
Gram Positive Bacteria ◽  
Catalytic Sites ◽  
Major Chemical ◽  
Bacteria And Fungi

The essential oil of Siparuna guianensis was obtained by hydrodistillation. The identification of the chemical compounds was performed by gas chromatography coupled with mass spectrometry (GC/MS). Antimicrobial activity was investigated for four microorganisms: Streptococcus mutans (ATCC 3440), Enterococcus faecalis (ATCC 4083), Escherichia coli (ATCC 25922), and Candida albicans (ATCC-10231). The studies of doping and molecular dynamics were performed with the molecule that presented the highest concentration of drug–target proteins, 1IYL (C. albicans), 1C14 (E. coli), 2WE5 (E. faecalis), and 4TQX (S. mutans). The main compounds identified were: Curzerene (7.1%), γ-Elemene (7.04%), Germacrene D (7.61%), trans-β-Elemenone (11.78%), and Atractylone (18.65%). Gram positive bacteria and fungi were the most susceptible to the effects of the essential oil. The results obtained in the simulation showed that the major compound atractylone interacts with the catalytic sites of the target proteins, forming energetically favourable systems and remaining stable during the period of molecular dynamics.

scholarly journals Antimicrobial Characterization of Erythorbyl Laurate for Practical Applications in Food and Cosmetics

2020 ◽  
Vol 2020 ◽  
pp. 1-8
Author(s):  
Jin-Woo Kim ◽  
Hyunjong Yu ◽  
Kyung-Min Park ◽  
Pahn-Shick Chang
Keyword(s):  
Antibacterial Activity ◽  
Skin Diseases ◽  
Gram Positive ◽  
Multifunctional Additive ◽  
Water Emulsion ◽  
Practical Applications ◽  
Gram Positive Bacteria ◽  
Food Borne ◽  
Bacteria And Fungi ◽  
Oil In Water Emulsion

In this study, antimicrobial spectrum of erythorbyl laurate (EL) against bacteria and fungi, leading to food-borne and infectious skin diseases, was evaluated for its practical applications in food and cosmetics. Furthermore, the influences of environmental factors including pH, oxidative stress, and dispersion medium on antimicrobial activity of EL were investigated. The three Gram-positive bacteria and the three molds were susceptible to 3.0 mM EL, while the yeast was susceptible to 6.0 mM EL. It was demonstrated EL retained antibacterial activity against Staphylococcus aureus after being oxidized while the antibacterial activity against the three Gram-positive bacteria including S. aureus, Bacillus cereus, and Listeria monocytogenes was significantly enhanced as decrease of pH from 7.0 to 5.0. Moreover, EL exhibited bactericidal effects against both Gram-positive and Gram-negative bacteria in an oil-in-water emulsion. Treatment of 5.0 mM EL for 4 h reduced 5.29 ± 0.24, 6.01 ± 0.18, 5.95 ± 0.13, and 6.24 ± 0.30 log CFU/mL against S. aureus, L. monocytogenes, Pseudomonas aeruginosa, and Escherichia coli, respectively. In a multipassage resistance selection study, it was observed minimum inhibitory concentrations of EL against S. aureus were not increased over 20 passages, indicating EL might not develop drug resistance of bacteria. This study suggests EL has a potential to be applied as the multifunctional additive in food and cosmetics.

scholarly journals Antibacterial and Antifungal Activity of Three Monosaccharide Monomyristate Derivatives

Molecules ◽  
2019 ◽  
Vol 24 (20) ◽  
pp. 3692 ◽  
Author(s):  
Jumina ◽  
Mutmainah ◽  
Purwono ◽  
Kurniawan ◽  
Syah
Keyword(s):  
Antibacterial Activity ◽  
Antifungal Activity ◽  
Myristic Acid ◽  
Antimicrobial Agents ◽  
Mass Spectral ◽  
Food Industries ◽  
Gram Positive Bacteria ◽  
Microbial Infections ◽  
Antibacterial And Antifungal ◽  
Weak Antibacterial Activity

Microbial infections remains a serious challenge in food industries due to their resistance to some of the well-known antibacterial and antifungal agents. In this work, a novel monomyristoyl ester (fructosyl monomyristate) and two other derivatives (i.e., glucosyl and galactosyl monomyristates) were successfully synthesized from myristic acid and monosaccharides in two-step reactions. First, the myristic acid was converted to myristoyl chloride, and then the myristoyl chloride was reacted with fructose, glucose and galactose separately to produce the corresponding monosaccharide monomyristate derivatives. The structures of the synthesized products were confirmed by Fourier transform infrared (FTIR), proton and carbon nuclear magnetic resonance (1H- and 13C-NMR), and mass spectral (MS) data. The monomyristates esters were obtained in reaction yields of 45.80%–79.49%. The esters were then evaluated for their antimicrobial activity using the disc diffusion test. It was found that the esters exhibited a medium antibacterial activity against gram-positive bacteria; however, they showed a weak antibacterial activity against gram-negative bacteria. Amongst the esters, galactosyl myristate yielded the highest antibacterial activity against Salmonella typhimurium, Staphylococcus aureus and Bacillus subtilis, while glucosyl monomyristate exhibited the highest antibacterial activity only against Escherichia coli. Additionally, all products showed remarkable antifungal activity against Candida albicans. These findings demonstrate that monosaccharide monomyristate derivatives are promising for use as biocompatible antimicrobial agents in the future.

scholarly journals Synthesis of cyclotetrapeptide analogues of c-PLAI and evaluation of their antimicrobial properties

2021 ◽  
Vol 8 (3) ◽  
Author(s):  
Rani Maharani ◽  
Orin Inggriani Napitupulu ◽  
Jelang M. Dirgantara ◽  
Ace Tatang Hidayat ◽  
Dadan Sumiarsa ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Antimicrobial Properties ◽  
Trichophyton Mentagrophytes ◽  
Solution Phase ◽  
Gram Negative Bacteria ◽  
Gram Negative ◽  
Aromatic Residues ◽  
Gram Positive Bacteria ◽  
Lysine Residues ◽  
Bacteria And Fungi

Antimicrobial peptides (AMPs) are interesting compounds owing to their ability to kill several pathogens. In order to identify new AMPs, c-PLAI analogues were synthesized and evaluated together with their linear precursors for their antimicrobial properties against two Gram-positive bacteria ( Staphylococcus aureus and Bacillus cereus ), two Gram-negative bacteria ( Escherichia coli and Klebsiella pneumoniae ), and two fungal strains ( Candida albicans and Trichophyton mentagrophytes ). The new c-PLAI analogues were prepared through a combination of solid- and solution-phase syntheses, as previously employed for the synthesis of c-PLAI. The antimicrobial activity tests showed that the synthetic parent peptide c-PLAI was inactive or weakly active towards the bioindicators employed in the assay. The tests also indicated that cyclic c-PLAI analogues possessed enhanced antimicrobial properties against most of the bacteria and fungi tested. Furthermore, this study revealed that analogues containing cationic lysine residues displayed the highest activity towards most bioindicators. A combination of lysine and aromatic residues yielded analogues with broad-spectrum antimicrobial properties.

scholarly journals Antimicrobial effect, electronic and structural correlation of nano-filled Tin Bismuth metal alloys for biomedical applications

2019 ◽  
Vol 9 (5) ◽  
pp. 4340-4344
Keyword(s):  
Biomedical Applications ◽  
Low Cost ◽  
Antimicrobial Properties ◽  
Antimicrobial Effect ◽  
Chemical Precipitation ◽  
Gram Positive Bacteria ◽  
Antimicrobial Studies ◽  
Structural Correlation ◽  
Hall Effect Measurements ◽  
Nano Rods

In this work silver vanadate (AgVO3) nano-rods were successfully synthesized using chemical precipitation route and doped in hypo (Sn 99%- Bi 1% ) and hyper (Sn 3%- Bi 97% ) -eutectic tin-bismuth (Sn-Bi) alloy. Nanostructured metal alloy was synthesized using powder compact metallurgy technique as a new low cost and time-consuming route. Effects of the AgVO3 nano-rods content on the band structure of (Sn-Bi) alloy has been investigated through electronic transition studied via ATR ultraviolet/visible spectrophotometric and Hall Effect measurements. Antimicrobial studies for pathogenic Gram negative as well as Gram positive bacteria were also investigated and correlated to the analyzed electronic and optical properties. The work a debate avenue for probability controllingthe microbial growth and to correlate electronic properties of (Sn-Bi) alloy along with their antimicrobial properties.

scholarly journals DETERMINATION OF ANTIMICROBIALACTIVITY USING METHANOLIC EXTRACT OF PITHECELLOBIUM DULCE PLANT LEAVES.

2020 ◽  
pp. 1-3
Author(s):  
Mithaiwala Idris A. ◽  
Suthar Hetal S. ◽  
Hetvi Soni ◽  
Ojha Sunil ◽  
Agrawal Amit
Keyword(s):  
Pathogenic Bacteria ◽  
Inhibitory Effect ◽  
Plant Leaves ◽  
Bacterial Diseases ◽  
Gram Positive Bacteria ◽  
Soxhlet Method ◽  
Bacteria And Fungi ◽  
Antibacterial And Antifungal ◽  
Constitutional Analysis

Present days due to the pathogenic bacteria and fungi, the human mortality rate has increased in number. The synthetic antimicrobial and antifungal are used in the treatment of various fungal and bacterial diseases, but have various side effects which limit's their use. Traditionally Pithecellobium dulce plant has been used for treatment of antifungal and antimicrobial infection. In this article we are comparing the activity of antimicrobial and antifungal properties of Pithecellobium dulce plant using leaves extract on gram negative bacteria,gram positive bacteria and fungi.Methanolic extraction of Pithecellobium dulce leaves was carried out using Soxhlet method and the phyto constitutional analysis was carried out for presenceof alkaloids, avonoids, glycosides, saponins, phytosterols, and triterpenoids.The inhibitory effect was determined by Cup plate method, by the measurement of zone of inhibition.The outcome was the leaves extract consisted of active phytoconstituents which were phenols, glycoside, sugar and avanoid due to which the extract showed signicant zone of inhibition,by which property of antibacterial and antifungal was listed. It can be concluded that the leaves of Pithecellobium dulce consist of active phytoconstituents which can be used as potent antimicrobials

scholarly journals Antibacterial and Antifungal Activities of Rumex Confertus Willd

2021 ◽  
Vol 9 (12) ◽  
pp. 855-856
Author(s):  
G. D. Shermatova
Keyword(s):  
Antibacterial Activity ◽  
Ethyl Acetate ◽  
Gram Positive ◽  
Antifungal Activities ◽  
Gram Positive Bacteria ◽  
Root Part ◽  
Fungal Activity ◽  
Antibacterial And Antifungal Activities ◽  
Antibacterial And Antifungal

Abstract: The leaves and roots of Rumex confertus Willd were tested in vitro for antibacterial and fungal activity in the fractions of gasoline, chloroform, ethyl acetate and butanol. As a result, it was found that the leaves of the Rumex confertus Willd plant, chloroform and ethyl acetate fractions of the root part have antibacterial activity against fungi and gram-positive bacteria. Keywords: Rumex confertus Willd, fractions, extracts, antibacterial, antifungal

In vitro effectiveness of antimicrobial properties of propolis and chlorhexidine on oral pathogens: A comparative study

2020 ◽  
Vol 1 (3) ◽  
pp. 116-125
Author(s):  
Hadis Tavafi ◽  
Maryam- sadat Sadrzadeh-Afshar ◽  
Soroush Niroomand
Keyword(s):  
Periodontal Disease ◽  
Antimicrobial Properties ◽  
Bacterial Strains ◽  
Microdilution Method ◽  
Broth Microdilution Method ◽  
Microbial Strains ◽  
Bacteria And Fungi ◽  
Antibacterial And Antifungal ◽  
Oral Conditions

Periodontal disease is one of the most prevalent infectious oral conditions in the present century, and it is necessary to conduct research to find a solution to overcome these diseases. A variety of microbial strains of bacteria and fungi are involved in the pathogenesis of periodontal disease. The use of chemical agents such as mouthwashes is one of the strategies to control these diseases. The purpose of the present study was to compare the antimicrobial effects of propolis and chlorhexidine gluconate (CHX) on the bacterial strains of Streptococcus mutans, Streptococcus pyogenes, Staphylococcus aureus, Enterococcus faecalis, Pseudomonas aeruginosa, and the yeast strain of Candida albicans using the broth microdilution method. The results showed the inhibitory and microbicidal activities of the two substances against the tested microbial strains. The antibacterial and antifungal effects of CHX were more effective reported in this study than that of propolis against the studied pathogens. The results of this study also indicated that the propolis was less effective in inhibiting bacterial growth than the CHX. In addition, the combination of these two solutions had a synergistic effect on inhibition of other studied strains, with the exception of C. albicans and S. aureus. There is a need for further research on strains isolated from oral biofilm to achieve complementary results.

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