scholarly journals Anti Necrotic and Anticlastogenic Effect of Aloe Vera Extract in Swiss Albino Mice

Med One ◽  
2017 ◽  
Keyword(s):  
Aloe Vera ◽  
Swiss Albino Mice ◽  
Anticlastogenic Effect ◽  
Albino Mice

scholarly journals RADIOPROTECTION OF ALOE VERA AGAINST BIOCHEMICAL ALTERATIONS IN SWISS ALBINO MICE

2018 ◽  
Vol 10 (3) ◽  
pp. 55
Author(s):  
Priyanka Dadupanthi
Keyword(s):  
Radiation Treatment ◽  
Radical Scavenging Activity ◽  
Radical Scavenging ◽  
Aloe Vera ◽  
Radiation Energy ◽  
Tissue Water ◽  
Swiss Albino Mice ◽  
Biochemical Alterations ◽  
Radiation Induced ◽  
Albino Mice

Objective: In this study, radioprotection against radiation-induced hepatic damage in Swiss Albino Mice has been observed by Aloe vera. When individuals are exposed, the radiation energy is absorbed by the biological systems, which causes radiolysis of tissue water and generates free radicals.Methods: Animals were given Aloe vera leaf extract orally 1000 mg/kg body weight/day for 15 consecutive days before radiation exposure 0.5, 3 and 5.5 Gy gamma radiation. Mice were autopsied at day ¼, 1, 3, 5,10 and 20 after irradiation to evaluate the radio modulator effect in terms of LPO and GSH.Results: Radiation treatment showed a decrease in GSH content and an increase of LPO in control set animals, however, the animals of experimental group i.e. Aloe vera and radiation combined group showed a significant increase in GSH content and decrease in LPO but values remained below normal.Conclusion: The result of present study suggests that Aloe vera has a radioprotective effect due to their antioxidant and radical scavenging activity.

scholarly journals Prevention of radiation-induced hepatic damage in Swiss albino mice by Aloe Vera leaf extract

2010 ◽  
Vol 25 (3) ◽  
pp. 186-191 ◽  
Author(s):  
Prashasnika Gehlot ◽  
Dhanraj Soyal ◽  
Pradeep Goyal
Keyword(s):  
Lipid Peroxidation ◽  
Alkaline Phosphatase ◽  
Acid Phosphatase ◽  
Leaf Extract ◽  
Aloe Vera ◽  
Swiss Albino Mice ◽  
Radiation Induced ◽  
Albino Mice ◽  
Effects Of Radiation ◽  
Induced Changes

The radioprotective effect of the Aloe vera leaf extract was studied in Swiss albino mice against radiation-induced changes in the liver. The mice were treated with 1000 mg/kg of body weight orally, once a day for 15 consecutive days, before exposure to a single dose of gamma radiation (6 Gy), half an hour after the last administration. The irradiation of mice caused a significant elevation in lipid peroxidation followed by a decrease in glutathione, acid phosphatase and alkaline phosphatase. The treatment of mice before irradiation elevated the glutathione, acid phosphatase and alkaline phosphatase, and was accompanied by a decline in lipid peroxidation. Recovery and regeneration from radiation damage were faster in pretreated animals than the animals in the irradiation-only group. The data clearly indicate that the Aloe vera leaf extract significantly reduced the deleterious effects of radiation on the liver and it could be a useful agent in reducing the side effects of therapeutic radiation.

Protective Effects of Prunus Avium Extract on 10 Ghz Induced Damages in the Spleen of Swiss Albino Mice

2011 ◽  
Vol 3 (8) ◽  
pp. 680-684 ◽  
Author(s):  
Faiza Rifat ◽  
◽  
Archana Sharma ◽  
Preeti Srivastava ◽  
Shikha Patni ◽  
...  
Keyword(s):  
Prunus Avium ◽  
Protective Effects ◽  
Swiss Albino Mice ◽  
Albino Mice
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