scholarly journals Immune Transformations in Primary and Secondary Syphilis Patients before and after Treatment and its Clinical Significance

2017 ◽  
Vol 9 ◽  
pp. 5-11
Author(s):  
Sedzro Divine Mensah ◽  
Li Huiling ◽  
Zhang Xiaoli ◽  
Wang Yong ◽  
Zhang Yanlai ◽  
...  
Keyword(s):  
Clinical Significance ◽  
Secondary Syphilis ◽  
Before And After

scholarly journals Clinical significance of circulating tumor cell related markers in patients with epithelial ovarian cancer before and after adjuvant chemotherapy

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Meysam Yousefi ◽  
Sara Rajaie ◽  
Vahideh Keyvani ◽  
Somayeh Bolandi ◽  
Malihe Hasanzadeh ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Adjuvant Chemotherapy ◽  
Epithelial Ovarian Cancer ◽  
Clinical Significance ◽  
Therapy Response ◽  
Serum Levels ◽  
Circulating Tumor Cell ◽  
Tumor Stage ◽  
Disease Stage ◽  
Before And After

AbstractCirculating tumor cells (CTCs) have recently been considered as new prognostic and diagnostic markers for various human cancers; however, their significance in epithelial ovarian cancer (EOC) remains to be elucidated. In this study, using quantitative real-time PCR, we evaluated the expression of EPCAM, MUC1, CEA, HE4 and CA125 mRNAs, as putative markers of CTCs, in the blood of 51 EOC patients before and/or after adjuvant chemotherapy. Our results demonstrated that, before chemotherapy, the expression of EPCAM, MUC1, CEA and HE4 mRNAs were correlated to each other. CEA expression was correlated with tumor stage (r = 0.594, p = 0.000) before chemotherapy, whereas its expression after chemotherapy was correlated with serum levels of CA125 antigen (r = 0.658, p = 0.000). HE4 mRNA showed the highest sensitivity both before and after chemotherapy (82.98% and 85.19%, respectively) and the persistence of this marker after chemotherapy was associated with advanced disease stage. The expression of CA125 mRNA had negative correlation with the other markers and with tumor stage and therapy response (evaluated by the measurement of serum CA125 antigen). Collectively, our results indicated a better clinical significance of tumor-specific markers (CEA and HE4 mRNAs) compared to epithelial-specific markers (EPCAM and MUC1 mRNAs).

Chemotherapy of Advanced Seminoma: Clinical Significance of Radiological Findings before and after Treatment

1989 ◽  
Vol 64 (5) ◽  
pp. 530-534 ◽  
Author(s):  
SOPHIE D. FOSSÅ ◽  
G. KULLMANN ◽  
H. H. LIEN ◽  
ANNA E. STENWIG ◽  
S. OUS
Keyword(s):  
Clinical Significance ◽  
Radiological Findings ◽  
Before And After

Shaping Ability of ProTaper Next, WaveOne, and Reciproc in Simulated Root Canals

2016 ◽  
Vol 17 (11) ◽  
pp. 902-906
Author(s):  
Mateus R Tonetto ◽  
EM Maia Filho ◽  
RM dos Reis Santos ◽  
Darlon M Lima ◽  
SM da Silva Pereira ◽  
...  
Keyword(s):  
Clinical Significance ◽  
Root Canal ◽  
Negative Impact ◽  
Endodontic Treatment ◽  
Root Canals ◽  
Before And After ◽  
Reciprocating Instruments ◽  
Shaping Ability ◽  
Curved Root Canals

ABSTRACT Introduction The study aimed to compare the shaping and preservation of the original curvature of simulated curved root canals using the following instruments: Reciproc (Rcp), WaveOne (Wo), and the ProTaper Next system (Ptn). Materials and methods A total of 45 resin blocks with simulated curved root canals were divided into three groups (n = 15), prepared using the Rcp (R25), Wo (25/0.8), and Ptn (X2) instruments. Standardized photographs were taken before and after canal instrumentation. After the superimposition of the images, the amount of resin removed from the curvature's inner and outer walls was measured at six apical levels, at intervals of 1 mm. The canals’ angles of curvature before and after instrumentation were subtracted. Results There were no significant differences between the instruments in terms of the total amount of resin removed of the inner or outer walls of the apical curvature (p > 0.05). The Rcp instruments provided the best resin removed ratios between the walls. The means of the change in angle were as follows: Wo = 2.15°, Ptn = 0.92°, and Rcp = 0.21°. WaveOne caused significantly higher deviations than Rcp. Conclusion All of the instruments demonstrated a tendency to straighten the simulated root canal. Instruments that use rotary movement achieved an effect similar to that of the reciprocating instruments in relation to change in angle. Clinical significance Deviations from the original shape of the root canal could have a negative impact on the quality of a filling and consequently on the success of the endodontic treatment. How to cite this article Maia Filho EM, dos Reis Santos RM, Lima DM, da Silva Pereira SM, Soares JA, de Jesus Tavarez RR, Ferreira MC, Carvalho CN, Bandeca MC, Tonetto MR, Borges AH, de Castro Rizzi C. Shaping Ability of ProTaper Next, WaveOne, and Reciproc in Simulated Root Canals. J Contemp Dent Pract 2016;17(11):902-906.

Middle ear pressures in patients with nasopharyngeal carcinoma and their clinical significance

1995 ◽  
Vol 109 (5) ◽  
pp. 390-393 ◽  
Author(s):  
W. K. Low
Keyword(s):  
Nasopharyngeal Carcinoma ◽  
Clinical Significance ◽  
Middle Ear ◽  
Newly Diagnosed ◽  
Middle Ear Effusion ◽  
Post Irradiation ◽  
Before And After ◽  
The Mean ◽  
Ear Effusion ◽  
Made In

AbstractThere is a paucity of studies investigating middle ear pressures (MEPs) in patients with nasopharyngeal carcinoma (NPC). This paper prospectively examines MEPs in patients with nasopharyngeal carcinoma before and after radiotherapy and discusses their clinical significance. Newly diagnosed patients with nasopharyngeal carcinoma were studied before and at three to 12 months (mean 7.5 months) after radiotherapy. MEPs were measured by tympanometry. Thirty-three patients completed the study. The mean MEP before and after radiotherapy was −55.2 mm water(range −250 to 45 mm water) and −73.1 mm water (range −215 to 35 mm water) respectively. About two-thirds of assessable ears had an increase in negative MEPs after irradiation and the rest had less negative MEPs after irradiation. Those ears which developed post-irradiation middle ear effusions were found to have pre-irradiation negative middle ear pressures of at least −45 mm water. These findings provide possible explanations for some unexplained audiometric observations previously made in patients with nasopharyngeal carcinoma after radiotherapy. Tympanometry before radiotherapy may prove to be useful in identifying ears with a high risk of developing post-irradiation middle ear effusion.

scholarly journals Changes in bowel sounds of inpatients undergoing general anesthesia

2020 ◽  
Author(s):  
Guojing Wang ◽  
Mingjun Wang ◽  
Hongyun Liu ◽  
Suping Zhao ◽  
Lu Liu ◽  
...  
Keyword(s):  
General Anesthesia ◽  
Clinical Significance ◽  
Nonlinear Characteristic ◽  
Intestinal Function ◽  
Bowel Sounds ◽  
Before And After ◽  
Feeding Methods ◽  
Characteristic Values ◽  
Linear And Nonlinear ◽  
Postoperative Feeding

Abstract Background: General anesthesia can affect intestinal function, but there is no objective, practical and effective indicator to evaluate the inhibition and recovery of intestinal function. The main objectives of this study were to assess whether bowel sounds (BSs) changed before, immediately after and 3 hours after general anesthesia, and whether these changes in BSs are an effective indicator of intestinal function and an accurate guide for post-operative feeding. Methods: We randomly selected 26 inpatients and collected three sets of 5-minute continuous BS data before the operation (Pre-op), immediately after the operation (Pro-op) and three hours after the operation (3h-Pro-op) for each patient. Then the linear and nonlinear characteristic values (CVs) of each EBS were extracted and paired t -tests and rank-sum tests were used to evaluate the changes in the BSs. Results: The differences in CVs, between Pre-op and Pro-op, as well as between Pro-op and 3h-Pro-op, were statistically significant ( p <0.05). However, there is no statistically significant differences between all the CVs between Pre-op and 3h-Pro-op ( p >0.05). Conclusion: BSs changes before and after general anesthesia. Furthermore, the BSs are weakened due to general anesthesia and recover to the pre-op state three hours later. Therefore, the BSs can be an indicator of intestinal function under general anesthesia, so as to provide guidance for postoperative feeding , which is of considerable clinical significance.

scholarly journals Clinical significance of liver function indexes in patients before and after ERCP

2013 ◽  
Vol 21 (18) ◽  
pp. 1772
Author(s):  
Wen Song ◽  
Ping Bo ◽  
Chao-Wu Chen ◽  
Jun Liu ◽  
Deng-Hao Deng ◽  
...  
Keyword(s):  
Liver Function ◽  
Clinical Significance ◽  
Before And After

scholarly journals Clinical significance of centripetal propagation of vasoconstriction in patients with reversible cerebral vasoconstriction syndrome: A retrospective case-control study

Cephalalgia ◽  
2018 ◽  
Vol 38 (12) ◽  
pp. 1864-1875 ◽  
Author(s):  
Masami Shimoda ◽  
Shinri Oda ◽  
Hideaki Shigematsu ◽  
Kaori Hoshikawa ◽  
Masaaki Imai ◽  
...  
Keyword(s):  
Magnetic Resonance ◽  
Magnetic Resonance Angiography ◽  
Clinical Significance ◽  
Thunderclap Headache ◽  
Reversible Cerebral Vasoconstriction Syndrome ◽  
Retrospective Case ◽  
Cerebral Vasoconstriction ◽  
Increased Risk ◽  
Before And After ◽  
Control Study

Introduction We previously reported centripetal propagation of vasoconstriction at the time of thunderclap headache remission in patients with reversible cerebral vasoconstriction syndrome. Here we examine the clinical significance of centripetal propagation of vasoconstriction. Methods Participants comprised 48 patients who underwent magnetic resonance angiography within 72 h of reversible cerebral vasoconstriction syndrome onset and within 48 h of thunderclap headache remission. Results In 24 of the 48 patients (50%), centripetal propagation of vasoconstriction occurred on magnetic resonance angiography at the time of thunderclap headache remission. The interval from first to last thunderclap headache in patients with centripetal propagation of vasoconstriction (14 ± 10 days) was significantly longer than that of patients without centripetal propagation of vasoconstriction (4 ± 2 days). In the patients with centripetal propagation of vasoconstriction at the time of thunderclap headache remission, the incidence of another cerebral lesion (38%, 9 of 24 cases) was significantly higher than in patients without centripetal propagation of vasoconstriction (0%). From findings of sequential magnetic resonance angiography before and after thunderclap headache remission, we observed tendencies in which centripetal propagation of vasoconstriction gradually progressed after the onset of reversible cerebral vasoconstriction syndrome and peaked at the time of thunderclap headache remission. The progress of centripetal propagation of vasoconstriction concluded with thunderclap headache remission. Conclusions Centripetal propagation of vasoconstriction has clinical significance as an indicator of the severity of reversible cerebral vasoconstriction syndrome. The presence of centripetal propagation of vasoconstriction is associated with an increased risk of brain lesions and a longer interval from first to last thunderclap headache. Moreover, repeat magnetic resonance angiography to assess centripetal propagation of vasoconstriction during the time from onset to thunderclap headache remission can help diagnose reversible cerebral vasoconstriction syndrome.

The clinical significance of hematocrit values before and after percutaneous coronary intervention

2009 ◽  
Vol 158 (6) ◽  
pp. 1024-1030 ◽  
Author(s):  
Gabriel Maluenda ◽  
Gilles Lemesle ◽  
Sara D. Collins ◽  
Itsik Ben-Dor ◽  
Asmir I. Syed ◽  
...  
Keyword(s):  
Percutaneous Coronary Intervention ◽  
Clinical Significance ◽  
Coronary Intervention ◽  
Percutaneous Coronary ◽  
Before And After
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