scholarly journals PENGARUH LUMATAN DAUN PLETEKAN (Ruellia Tuberosa L) TERHADAP LAMA PENUTUPAN LUKA PADA TIKUS PUTIH (Rattus Novergicus)

2017 ◽  
Vol 4 (2) ◽  
pp. 104
Author(s):  
Ria Susana ◽  
Rismia Agustina ◽  
Abdurahman Wahid

ABSTRAKLuka didefinisikan sebagai gangguan pada fungsi dan integritas jaringan tubuh. Penyembuhan luka merupakan proses yang kompleks dari perbaikan dan remodeling jaringan sebagai respon terhadap cedera. Pletekan (ruellia tuberosa l) mengandung flavonoid, glikosida, phenol, saponin dan nutrisi yang diharapkan mempercepat penyembuhan luka. Tujuan penelitian ini adalah mengidentifikasi pengaruh  lumatan daun pletekan (ruellia tuberosa l) terhadap lama penutupan luka pada tikus putih (rattus novergicus). Penelitian ini merupakan studi eksperimental dengan rancangan posttest only control, menggunakan teknik simple random sampling. Sampel yang digunakan sebanyak 40 ekor tikus jantan dengan luka insisi bersih sepanjang 3 cm yang dibagi menjadi 2 kelompok yaitu kelompok kontrol dan kelompok perlakuan. Data yang diukur adalah rata-rata lama penutupan luka. Data yang diperoleh dianalisis menggunakan uji mann-whitney dengan derajat kepercayaan 95% menunjukkan perbedaan yang signifikan rata-rata lama penutupan luka antara kelompok kontrol (8,45) dan kelompok perlakuan (3,75) dengan p-value 0,000 (p<0,05). Kesimpulan penelitian ini adalah terdapat pengaruh lumatan daun  pletekan (ruellia tuberosa l) terhadap lama penutupan luka pada tikus putih (rattus novergicus).Kata-kata kunci: luka insisi bersih, pletekan (ruellia tuberosa l), lama penutupan luka.ABSTRACTWounds is defined as disruption of the function and integrity of body tissues. Wound healing isa complex process of tissue repair and remodelling in response to injury. Pletekan (ruellia tuberosa l) contains flavonoids, glycosides, phenols, saponins and nutritive value that suppose to accelerate wound healing. The purpose of this study was to identify the effect of pletekan leaves (ruellia tuberosa) to wound closure time in rats (rattus novergicus). This research was an experimental study with post- test design using the simple random sampling technique. The samples were 40 male rats with a clean incision wound along 3 cm which were divided into two groups, control group and treatment group. The measured data were the average of wound closure time. Data were analyzed using the mann- whitney test with 95 % confidence level showed a significant difference between the control group (8,45) and the treatment group (3,75) with p-value 0,000 (p<0,005). There was significant effect of ruellia tuberosa l to wound closure time in rattus novergicus.Keywords: wounds, ruellia tuberosa , wound closure time.

Author(s):  
Idola Perdana Sulistyoning Suharto

The research purpose was to analysis effect of giving mahkota dewa fruits (Phaleria macrocarpa) extract to epithelialization in incision wound of white rats (Rattus norvegicus). The method was randomized posted-only control group design. There were 30 male rats (Rattus norvegicus) grouped on control and treatment group. Control group divided into three groups (KK1, KK2, KK3) and also treatment group divided into three groups (KP1, KP2, KP3). Control group just given CMC 1% peroral without mahkota dewa fruits extract, the treatment group given mahkota dewa fruits extract 22.5 mg/kg body weight. The data was analyzed by Kruskall Wallis. Based on Kruskall Wallis test, obtained result that there was a significant difference (p<0.05) epithelialization variable with p value p = 0.000 between control and treatment group. And based on One-way Anova test, obtained result that there was a significant difference (p<0.05) with p value p =0.000 between control and treatment group. The conclusion of this research was giving mahkota dewa fruits (Phaleria macrocarpa) extract can increase epithelialization in incision wound of white rats (Rattus norvegicus). Keywords : Mahkota Dewa Fruits (Phaleria Macrocarpa) Extract, Epithelialization, Incision Wound 


2018 ◽  
Vol 3 (2) ◽  
pp. 89
Author(s):  
Rizky Gumilang Pahlawan ◽  
Budi Rustandi ◽  
Lisbet Octovia Manalu

ABSTRAKTujuan Penelitian: mengetahui pengaruh pendidikan kesehatan tentang infeksi saluran pernapasan akut (ISPA) terhadap tingkat pengetahuan ibu dalam perawatan balita ISPA. Metode: quasy experimental dengan pendekatan non equivalent control group. Penarikan sampel pada penelitian ini menggunakan teknik simple random sampling dengan jumlah responden sebanyak 45 ibu yang mempunyai balita ISPA, dibagi menjadi kelompok perlakuan dan kontrol. Pengumpulan data dilakukan menggunakan kuesioner dengan 25 item pertanyaan yang sudah diuji validitas dan reliabilitasnya. Pada kelompok perlakuan dilakukan pendidikan kesehatan dengan cara metode seminar, diskusi dan tanya jawab serta memberikan leaflet sedangkan pada kelompok kontrol tidak dilakukan pendidikan kesehatan. Pengumpulan data dilakukan pada bulan Mei sampai Agustus 2015. Tehnik analisis data menggunakan uji statistic marginal homogeneity. Hasil: Rentang umur responden adalah 27-35 tahun. Mayoritas tingkat pengetahuan ibu pada saat pretest masuk dalam kategori kurang, yaitu (74%) pada kelompok perlakuan dan (86,4%) kelompok kontrol dengan p value 0,05. Tingkat pengetahuan pada saat post test didapatkan hasil yang berbeda yaitu 82,5% kategori baik pada kelompok perlakuan dan 91,1% kategori kurang pada kelompok kontrol dengan p value 0,05. Tingkat pengetahuan responden pada penelitian ini menunjukan adanya pengaruh yang signifikan antara pendidikan kesehatan terhadap tingkat pengetahuan ibu dengan nilai p value 0,01. Kesimpulan: Terdapat pengaruh antara pendidikan kesehatan dengan tingkat pengetahuan ibu balita ISPA. Dengan demikian, hasil penelitian ini penting sebagai bahan telaah bagi petugas puskesmas ataupun pelayanan kesehatan dalam upaya mencegah terjadinya ISPA.Kata kunci: balita, Infeksi saluran Pernapasan akut, pendidikan kesehatan, pengetahuanEFFECT OF HEALTH EDUCATION ON KNOWLEDGE LEVELS IN MOTHERS OF UNDER-FIVE CHILDREN WITH ARIABSTRACTObjective: To identify the effect of health education about acute respiratory infections (ARI) on the levels of knowledge in mothers of under-five children with ARI. Methods: This study is quasi-experimental with nonequivalent control group approach. Samples were taken using simple random sampling technique with a sample size of 45 mothers who had under- five children with ARI, whom were divided into treatment and control groups. Data were collected using a questionnaire with 25 items of questions of which validity and reliability had been tested. Health education was given to the treatment group through seminar, discussion, question and answer as well as leaflets, but not given to the control group. Data were collected from May to August 2015. Data were analyzed using a statistical test of marginal homogeneity. Results: The age range of respondents was 27-35 years. The majority of mothers’ level of knowledge at the time ofpretest was poor, which was (74%) in the treatment group and (86.4%) in the control group with p value of > 0.05. The level of knowledge at the time of the posttest indicated different results, that 82.5% belonged to good category in the treatment group and 91.1% belonged to poor category in the control group with p value of <0.05. The respondents’ level of knowledge in this study showed a significant effect of education health on mother’s level of knowledge with p value of <0.01. Conclusion:There is an effect of health education on levels of knowledge in mothers of under-five children with AR1. Therefore, the results of this study are important as a study material for public health center or health services staff in order to prevent the incidence of ARI.Keywords: under-five children, acute respiratory infections, health education, knowledge


2021 ◽  
Vol 33 (1) ◽  
pp. 48
Author(s):  
Nanda Amalia Ramadhanti ◽  
Willy Sandhika ◽  
Agung Dwi Wahyu Widodo

Background: Snakehead fish has been associated with wound healing due to its high albumin content. Albumin can accelerate the inflammatory process so that tissue repair will be faster. Lack of albumin protein causes a person tend to experience prolonged wound healing. Purpose: This study aims to prove the effect of snakehead fish extract on the number of macrophages and blood vessels on the inflammatory reaction of skin wound tissue in rats. Methods: Laboratory experimental design with a total sample size of 27 male rats have undergone incisions, divided into 3 random groups: control group was given aquadest, treatment group 1was given aquadest and 50% extract of snakehead fish, and treatment group 2 was given 100% extract of snakehead fish. The rat’s skin wound tissues were taken on day 5 and observed under the microscope. The average number of macrophages and blood vessels on granulation tissue that formed at the base of the wound were counted and then performed data analysis. Result: In this study, we found a down wards trend in the average number of macrophages and blood vessels in treatment group 1 and treatment group 2. The control group and the treatment group 2 showed a significant difference, however, between the other groups did not show significant difference. Conclusion: There is a significant effect of giving 100% snakehead fish extract on decreased macrophages and blood vessels in the inflammatory reaction of skin wound tissue.


2019 ◽  
Vol 6 (1) ◽  
pp. 056-062
Author(s):  
Maria Magdalena Setyaningsih ◽  
Emy Sutiyarsih ◽  
Eli Lea Widhia Purwandhani ◽  
Marta Indah Tri Rahayu

Menopause merupakan masa kritis kehidupan wanita, pada periode ini terjadi perubahan fisik maupun psikis. Pada periode inilah seorang wanita merasa dirinya menjadi tua dan takut tidak dapat memenuhi kebutuhan seksual suami, dengan bertambahnya usia masalah ini tidak harus terjadi. Tujuan penelitian adalah  menganalisis  Pengaruh  Pemberian  Paket  “Affection”  Terhadap Aktifitas  Seksual  Pada  Pasangan  Menopause.  Metode  yang  digunakan adalah Quasy eksperiment dengan desain penelitian Pretest Post test One Group  Design.  Populasi  dan  sampelnya  adalah  wanita  menopause  yang memiliki suami dan tidak menderita penyakit yang dapat mempengaruhi aktifitas seksual, sebanyak 20 wanita di dusun Wonosari sebagai kelompok perlakuan dan 20 wanita di dusun Sukosari sebagai kelompok kontrol dengan tehnik Simple Random Sampling. Berdasarkan hasil uji paired sample t test pada kelompok kontrol nilai signifikansi sebesar 0.514 > alpha 0.05 (p > 0.05), bahwa tidak ada perbedaan yang signifikan aktifitas seksual pada wanita menopause pada pre dan post intervensi. Pada kelompok perlakuan hasil uji t independent  nilai signifikansi sebesar 0.023 (p<0.05), bahwa terdapat pengaruh pemberian paket “Affection” terhadap peningkatan aktifitas seksual pasangan menopause. Aktifitas seksual wanita menopause pada kelompok perlakuan lebih tinggi daripada sebelum diberikan intervensi.  Oleh karena itu dianjurkan bagi petugas puskesmas untuk menindaklanjuti dengan me- ngembangkan program promosi kesehatan melalui penyebarluasan peman- faatan paket “Affection” bagi pasangan menapouse.  Menopause is a critical period of a woman’s life, during this period physi- cal and psychological changes might occur. During this period, a woman felt herself getting old and afraid if she cannot fulfill her husband sexual needs.  This  case  suppose  not  happend  eventhough  the  age  of  a  woman increasing.  The  purpose  of  the  research  is  to  analyze  Effects  of  Giving Affection  Packages  on  Sexual  Activities  in  Menopause  Couples.  That method used is Quasi experiment with Pretest Post test One Group Design research  design.  The  population  and  the  sample  is  menopausal  women who have  husbands and do not suffer from a disease that can affecting sexual activity, there were 20 women in Wonosari district as a treatment group  and  20  women  in  Sukosari  district  as  a  control  group  with  the Simple Random Sampling technique. Based on the results of study on paired sample t test in the control group with a significance value of 0.514 & gt; alpha  0.05  (p &  gt;  0.05),  there  was  no significant  difference  in  sexual activity in postmenopausal women in the pre and post intervention. On the treatment group the results of the independent t test significant value of 0.023 (p & lt; 0.05), there was an influence on giving “Affection” package to menopausal couples in the case of sexual activity. Women’s sexual activ- ity  on  menopausal  age  in  the  treatment  group  was  higher  than  before given intervention. Therefore It is recommended for puskesmas officers to follow up by developing health promotion programs through disseminat- ing the application of the “Affection” package for menapouse couples.


2018 ◽  
Vol 51 (1) ◽  
pp. 1
Author(s):  
Moh. Basroni Rizal ◽  
Elly Munadziroh ◽  
Indah Listiana Kriswandini

Background: Tooth extraction is the process of removing a tooth from the oral cavity potentially triggering a wound healing response in the body. As a result, many methods have been applied to improve the wound healing process, especially in wounds resulting in complications. One such method involves the application of amniotic membrane which has anti-inflammatory, anti-bacterial, anti-fibrosis, anti-scarring properties with low immunogenicity, epithelialization effects, and secretory leukocyte protease inhibitor (SLPI). It also contains collagen, various growth factors, transferrin, fibronectin, nidogen, proteoglycans, hyaluronan, and laminin. Purpose: This study aimed to determine the effects of sponge amnion on the number of VEGF expressions and new blood vessels in post-tooth extraction wounds of Wistar rats. Methods: Sponge amnion was produced by mixing freeze-dried amnion membrane from the Tissue Bank at RSUD Dr. Soetomo with 1% gelatin before freeze drying the mixture. Wistar rats were then divided into two groups. In Group 1, referred to as the control group, the post-extraction wounds of the rats received no treatment. Meanwhile, in Group 2, the treatment group, the subjects’ post-extraction wounds were treated with sponge amnion. The rats of both groups were sacrificed on day 3 to allow observation of the number of VEGF expressions and new blood vessels. A statistical analysis test, a t-test, was subsequently conducted. Results: There was a significant difference in the number of new blood vessels in the control group and that of the treatment group with a p value of 0.018 (p<0.05). There was also a significant difference in VEGF expression between the two groups with a p value of 0.000 (p <0.05). Conclusion: Sponge amnion can generate a number of VEGF expressions and new blood vessels in the post-extraction wounds of Wistar rats.


Author(s):  
Muhammad Kashif ◽  
Nosheen Manzoor ◽  
Rimsha Safdar ◽  
Hafsa Khan ◽  
Maryam Farooq ◽  
...  

BACKGROUND: Cervicogenic headache (CGH) is a common condition that results in significant disability. To treat this dysfunction, Mulligan described sustained natural apophyseal gliders (SNAGs) as a manual therapy approach. However, only inconclusive short-term evidence exists for treating CGH with SNAGs. OBJECTIVE: The present study aims to investigate the effect of SNAGs in the treatment of CGH. METHODS: Fourty female patients ranging from 20 to 40 years with CGH were randomly assigned to two groups: 20 in a treatment group and 20 in a control group. SNAGs were applied to the treatment group while the control group received placebo treatment. Both groups received their respective treatment for 20 minutes, alternately three times per week, for a total of 12 times in four weeks. The outcome measures were the Neck Disability Index (NDI) and the Visual Analogue Scale (VAS). Participants were assessed at baseline and at the end of each week. The data was analyzed using SPSS version 20. Independent t-testing was used to reveal changes between groups. One-way ANOVA was used to determine changes within groups. The level of significance was P< 0.05. RESULTS: Twenty participants (100%) in the treatment group and 17 (85%) in the control group had a history of headache aggravation with active movements or passive head positioning. There was no significant difference at baseline (p> 0.05), indicating that both groups were homogeneous at the time of recruitment. The p value (p< 0.05) showed a significant difference in pain and level of disability at three and four weeks (p< 0.05) in patients treated with SNAGs. However, the cervical range of motion (ROM) showed a statistically significant improvement in flexion and extension in the treatment group (p< 0.05) while there was no significant improvement in side flexion and rotation ROM in both groups (p> 0.05). CONCLUSION: This study found that SNAGs were effective in reducing pain and neck disability and improved ROM in females with CGH.


2021 ◽  
Vol 42 (Supplement_1) ◽  
pp. S193-S193
Author(s):  
Emre Karakaya ◽  
Aydincan Akdur ◽  
H Ebru ◽  
Ayvazoglu Soy ◽  
Alev Ok Atilgan ◽  
...  

Abstract Introduction Burn is one of the most severe traumas that causes coagulative destruction of the skin. The use of various products that accelerate wound healing in patients with burn may affect the patient’s survival and reduce the complications that may be seen. In the present study we aimed effects of subcutaneous ozone injection on second degree burn wound. Methods A total of 72 Sprague-Dawley male rats included in the study were divided randomly into three groups (control group (CG), silver sulfadiazine group (SG), ozone group (OG)) and each group was divided randomly two subgroups (as sacrificed on d7 and on d14).A deep second degree scald burns were created on the lower back. In CG subcutaneous 0.9% serum saline was injected daily into the burn area. In SG, burns were dressed with silver sulfadiazine daily and in OG subcutaneous ozone was injected daily into the burn area. Tissue hydroxyproline level measurement and histopathological evaluation were done. Results When the groups were compared in terms of weight change, no significant difference was found on the 7th and 14th days. In the evaluation made in terms of tissue hydroxyproline, tissue hydroxyproline level in OG was found to be significantly higher on both the 7th and 14th days (p &lt; 0.001). In histopathological evaluations, it was determined that wound healing in OG was significantly higher than in the other groups. Conclusions According to the results, subcutaneous ozone therapy is more effective than silver sulphadiazine in the healing process of second-degree burn wounds and it can be safely used in the treatment of burn wounds.


2015 ◽  
Vol 3 (3) ◽  
Author(s):  
I Gusti Bagus Magitojaya ◽  
Jehosua S. V. Sinolungan ◽  
Lydia David

Abstract: Nowadays, phenomeneon of juvenile delinquency has been spreading widely. Particularly to students, they usually perform juvenile delinquency that would harm themselves and finally trouble their minds due to consquences they are going to face. This study aimed to investigate the comparison of anxiety levels among students who performed juvenile delinquency. This was an analytical observational study with a cross sectional design. Subjects were 86 students of Swadharma Mopugad High School and Swadharma Werdhi Agung Senior High School obtained by using simple random sampling. Data were analyzed by using T independent test with α=0.005. The T independent test showed a t value of 0.457 and a p value of 0.649 (> 0.005) which indicated that there was no significant difference of anxiety levels among students who performed juvenile delinquency in both high schools. Conclusion: There was no significant difference between anxiety levels of students who performed juvenile delinquency in Swadharma Mopugad Senior High School and Swadharma Werdhi Agung Senior High School.Keywords: juvenile delinquency, anxietyAbstrak: Fenomena kenakalan remaja makin meluas dewasa ini. Hal ini tentunya dapat menimbulkan kecemasan pada siswa yang melakukannya mengingat sanksi yang bisa diperoleh akibat perbuatannya. Penelitian ini bertujuan untuk mengetahui perbandingan kecemasan siswa yang melakukan perilaku kenakalan remaja. Penelitian ini menggunakan metode analitik observasional dengan pendekatan potong lintang. Teknik pengambilan sampel yang digunakan yaitu simple random sampling. Subyek penelitian ialah siswa kelas XI SMA Swadharma Mopugad dan siswa kelas XI SMA Swadharma Werdhi Agung dengan jumlah total 86 siswa. Data dianalisis dengan uji T Independent (α = 0,005). Hasil uji T Independent mendapatkan nilai t sebesar 0,457, p = 0,649, yang menunjukkan tidak terdapat perbedaan tingkat kecemasan pada siswa yang melakukan kenakalan remaja di SMA Swadharma Mopugad dan SMA Swadharma Werdhi Agung. Simpulan: Tidak terdapat perbedaan tingkat kecemasan yang bermakna pada siswa yang melakukan kenakalan remaja di SMA Swadharma Mopugad dan SMA Swadharma Werdhi Agung.Kata kunci: kenakalan remaja, kecemasan


2017 ◽  
Vol 3 (5) ◽  
pp. 470-477
Author(s):  
Anjar Astuti ◽  
Suryono Suryono ◽  
Melyana Nurul Widyawati ◽  
Ari Suwondo ◽  
Mardiyono Mardiyono

Background: Autism is a neurodevelopmental disorder. Audio therapy is considered as one of the complementary therapies to improve the behavior of children with autism.Objective: This study was to analysis the effectiveness of the Al-Qur'an murrotal audio therapy on behavioral development in children with autism.Methods: This study was a true-experimental research using pretest and posttest approach with control group. This research was conducted on November 2016 in the Autism Foundation of Semarang City. There were 30 samples were selected using simple random sampling, with 15 samples assigned in the experiment and control group. Mann Whitney and Wilcoxon tests were used for data analysis in this study.Results: Results showed that there was a significant difference in the mean of behavioral development after given intervention between the experiment group and control group with p-value 0.034 (<0.05). The mean of behavioral development in the experiment group (4.53) was higher than the mean in the control group (3.47).Conclusion: The Al-Qur'an murrotal audio therapy is effective to develop behavior of children with autism. Therefore, it is expected that this audio therapy can be applied an alternative therapy for children with autism.


2016 ◽  
Vol 11 (1) ◽  
Author(s):  
Nova Fitriani Wahdah ◽  
A Wahab Jufri ◽  
Lalu Zulkifli

Abstrak. Penelitian ini bertujuan untuk menganalisis: (1) peningkatan kemampuan menulis jurnal belajar, (2) perbedaan kemampuan metakognisi siswa yang menulis jurnal belajar dengan siswa yang tidak menulis jurnal belajar, dan (3) hubungan kemampuan menulis jurnal belajar dengan kemampuan metakognisi siswa. Desain penelitian ini menggunakan nonequivalent control group design. Populasi dalam penelitian ini yaitu siswa kelas X dan kelas XI di SMAN 1 Pringgarata tahun ajaran 2014/2015 (285 orang). Sampel penelitian ditentukan melalui teknik simple random sampling. Sampel penelitian yang berjumlah 124 orang tersebar di kelas X3 dan XI IPA1 sebagai kelompok eksperimen, serta di kelas X2 danXI IPA2 sebagai kelompok kontrol. Instrumen penelitian berupa jurnal belajar, rubrik penilaian jurnal belajar, dan inventori kesadaran metakognisi. Data hasil penelitian dianalisis menggunakan program SPSS for windows 16. Hasil penelitian ini menunjukkan bahwa: (1) kemampuan siswa dalam menulis jurnal belajar mengalami peningkatan (N-gain= 0,2), (2) ada perbedaan kemampuan metakognisi antara siswa yang menulis jurnal belajar dengan siswa yang tidak menulis jurnal belajar (p < 0,05), dan (3) kemampuan menulis jurnal belajar berkorelasi positif dengan kemampuan metakognisi (p < 0,05).Kata kunci: jurnal belajar, kemampuan metakognisiAbstract. The aim of this research were  to analyze: (1) the improvement of students ability in journal writing skills, (2) the difference of metacognitive skills between students who wrote learning journal and those who did not write learning journal, (3) the correlation of journal writing skills and the metacognitive skills of students. The research design was used nonequivalent control group design. The Population of this research were students in X and XI class of SMAN 1 Pringgarata 2014/2015 (285 peoples). Sample of this research was determined by simple random sampling technique. The amount of sample were  124 peoples, that distributed in X3 and XI IPA1 classas experimental group,  X2 and XI IPA2  class as control group. The research instruments were learning journal, rubric of learning journal and metacognitive awareness inventory (MAI). Data in this research was analyzed by using SPSS for windows 16. The result of this research shows: (1) the students skills in writing journal was increase (N-gain = 0,2), (2) there were significant difference between students who wrote journal and those who did not write journal (p < 0,05), and (3) journal writing skills was positively correlated with the students metacognitive skill   (p < 0,05).Keywords: learning journal, metacognitive skills


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