scholarly journals Radiotherapy and the cellular DNA damage response: current and future perspectives on head and neck cancer treatment

2020 ◽  
Author(s):  
Maria Rita Fabbrizi ◽  
Jason L. Parsons
Keyword(s):  
Dna Damage ◽  
Head And Neck Cancer ◽  
Cancer Treatment ◽  
Head And Neck ◽  
Dna Damage Response ◽  
Neck Cancer ◽  
Future Perspectives ◽  
Damage Response ◽  
Cellular Dna ◽  
Response Current

scholarly journals Polymorphisms in DNA damage response genes and head and neck cancer risk

Biomarkers ◽  
2010 ◽  
Vol 15 (5) ◽  
pp. 379-399 ◽  
Author(s):  
Rafael E. Flores-Obando ◽  
Susanne M. Gollin ◽  
Camille C. Ragin
Keyword(s):  
Dna Damage ◽  
Head And Neck Cancer ◽  
Cancer Risk ◽  
Head And Neck ◽  
Dna Damage Response ◽  
Neck Cancer ◽  
Damage Response

scholarly journals Deficiencies in the Fanconi Anemia DNA Damage Response Pathway Increase Sensitivity to HPV-Associated Head and Neck Cancer

2010 ◽  
Vol 70 (23) ◽  
pp. 9959-9968 ◽  
Author(s):  
Jung Wook Park ◽  
Henry C. Pitot ◽  
Katerina Strati ◽  
Nicole Spardy ◽  
Stefan Duensing ◽  
...  
Keyword(s):  
Dna Damage ◽  
Head And Neck Cancer ◽  
Head And Neck ◽  
Dna Damage Response ◽  
Neck Cancer ◽  
Fanconi Anemia ◽  
Damage Response ◽  
Dna Damage Response Pathway

scholarly journals Incidence of Oral Mucositis in Patients Undergoing Head and Neck Cancer Treatment: Systematic Review and Meta-Analysis

2021 ◽  
Vol 5 (1) ◽  
pp. 23
Author(s):  
Raquel Pacheco ◽  
Maria Alzira Cavacas ◽  
Paulo Mascarenhas ◽  
Pedro Oliveira ◽  
Carlos Zagalo
Keyword(s):  
Systematic Review ◽  
Head And Neck Cancer ◽  
Oral Health ◽  
Cancer Treatment ◽  
Head And Neck ◽  
Neck Cancer ◽  
Oral Mucositis ◽  
Negative Impact ◽  
Meta Analysis ◽  
Incidence Rates

This systematic review and meta-analysis aimed to assess the literature about the incidence of oral mucositis and its degrees (mild, moderate, and severe), in patients undergoing head and neck cancer treatment (radiotherapy, chemotherapy, and surgery). Addressing this issue is important since oral mucositis has a negative impact on oral health and significantly deteriorates the quality of life. Therefore, a multidisciplinary team, including dentists, should be involved in the treatment. The overall oral mucositis incidence was 89.4%. The global incidence for mild, moderate, and severe degrees were 16.8%, 34.5%, and 26.4%, respectively. The high incidence rates reported in this review point out the need for greater care in terms of the oral health of these patients.

scholarly journals Targeting Protein-Protein Interactions in the DNA Damage Response Pathways for Cancer Chemotherapy

2021 ◽  
Author(s):  
Kerry Silva McPherson ◽  
Dmitry Korzhnev
Keyword(s):  
Dna Damage ◽  
Dna Damage Response ◽  
Protein Interactions ◽  
Cell Cycle Progression ◽  
Protein Protein Interactions ◽  
Cycle Progression ◽  
Damage Recognition ◽  
Damage Response ◽  
Cellular Dna ◽  
Dna Damage Recognition

Cellular DNA damage response (DDR) is an extensive signaling network that orchestrates DNA damage recognition, repair and avoidance, cell cycle progression and cell death. DDR alternation is a hallmark of...

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