scholarly journals Clinical significance of the loss of CD20 antigen on tumor cells in patients with relapsed or refractory follicular lymphoma

2021 ◽  
Author(s):  
Jean-Marie Michot ◽  
Alice Buet-Elfassy ◽  
Maxime Annereau ◽  
Julien Lazarovici ◽  
Alina Danu ◽  
...  
Keyword(s):  
Follicular Lymphoma ◽  
Tumor Cells ◽  
Clinical Significance ◽  
Cd20 Antigen

Author response for "Clinical significance of tryptophan catabolism in follicular lymphoma"

2020 ◽  
Author(s):  
Ayako Masaki ◽  
Takashi Ishida ◽  
Maeda Yasuhiro ◽  
Asahi Ito ◽  
Susumu Suzuki ◽  
...  
Keyword(s):  
Follicular Lymphoma ◽  
Clinical Significance ◽  
Author Response ◽  
Tryptophan Catabolism

scholarly journals Clinical significance of the WHO grades of follicular lymphoma in a population-based cohort of 505 patients with long follow-up times

2011 ◽  
Vol 156 (2) ◽  
pp. 225-233 ◽  
Author(s):  
Björn E. Wahlin ◽  
Olav E. Yri ◽  
Eva Kimby ◽  
Harald Holte ◽  
Jan Delabie ◽  
...  
Keyword(s):  
Follicular Lymphoma ◽  
Clinical Significance ◽  
Population Based

scholarly journals Circulating tumor cells and their clinical significance

2017 ◽  
Vol 67 (4) ◽  
pp. 243-250
Author(s):  
Ewa Anna Grzybowska ◽  
Anna Fabisiewicz
Keyword(s):  
Tumor Cells ◽  
Circulating Tumor Cells ◽  
Clinical Significance

scholarly journals Clinical significance of phenotyping and karyotyping of circulating tumor cells in patients with advanced gastric cancer

Oncotarget ◽  
2014 ◽  
Vol 5 (16) ◽  
pp. 6594-6602 ◽  
Author(s):  
Yilin Li ◽  
Xiaotian Zhang ◽  
Sai Ge ◽  
Jing Gao ◽  
Jifang Gong ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Advanced Gastric Cancer ◽  
Tumor Cells ◽  
Circulating Tumor Cells ◽  
Clinical Significance

Two for One: B-Cell Lymphomas with Features of Marginal and Follicular Lymphomas

2018 ◽  
Vol 139 (2) ◽  
pp. 84-88 ◽  
Author(s):  
Alexey Glazyrin ◽  
Chirag Patel ◽  
Lara Kujtan ◽  
Sheshadri Madhusudhana
Keyword(s):  
Bone Marrow ◽  
Follicular Lymphoma ◽  
Tumor Cells ◽  
Marginal Zone ◽  
Lymph Node Biopsy ◽  
Low Grade ◽  
Circulating Cells ◽  
Diagnosis And Classification ◽  
Follicular Lymphomas ◽  
Normal Architecture

Low-grade follicular lymphomas are genetically characterized by the translocation t(14; 18)(q32;q21) with BCL2 gene rearrangements. Marginal zone lymphomas are often associated with translocations or transcriptional deregulations of the MALT gene. We report 2 cases of lymphomas which harbor both the t(14;18)(q32;q21) translocation and MALT gene upregulation. Patients presented with numerous circulating atypical lymphocytes. Lymph node biopsy in both cases on HE staining demonstrated vague nodularity readily highlighted by CD10, CD23, or BCL6. Staining with CD20 and BCL2 demonstrated monotonous diffuse effacement of normal architecture with tumor cells without obvious follicular structures. Morphologically, tumor cells were consistent with centrocytes. Bone marrow biopsy demonstrated a combined peritrabecular and interstitial distribution of the tumor cells. These cases present substantial difficulties for diagnosis and classification. Clinical and morphological features were mostly consistent with follicular lymphoma, with a few features more often seen in marginal zone lymphomas (leukemic presentation, no CD10 in circulating cells, interstitial location of tumor cells in bone marrow); therefore, these cases were finally classified as follicular lymphoma grade I. Both patients were treated with standard chemotherapy regimens for follicular and nongastric MALT lymphomas with a good response to date.

Sign in / Sign up

Export Citation Format

Share Document