scholarly journals The role of exosomal long non-coding RNAs in cancer drug resistance

2019 ◽  
Author(s):  
Mireia Cruz De los Santos ◽  
Mihnea P. Dragomir ◽  
George A. Calin
Keyword(s):  
Drug Resistance ◽  
Cancer Drug ◽  
Cancer Drug Resistance ◽  
Non Coding Rnas

scholarly journals Role of intratumoural heterogeneity in cancer drug resistance: molecular and clinical perspectives

2012 ◽  
Vol 4 (8) ◽  
pp. 675-684 ◽  
Author(s):  
Nicholas A. Saunders ◽  
Fiona Simpson ◽  
Erik W. Thompson ◽  
Michelle M. Hill ◽  
Liliana Endo‐Munoz ◽  
...  
Keyword(s):  
Drug Resistance ◽  
Cancer Drug ◽  
Cancer Drug Resistance ◽  
Intratumoural Heterogeneity

scholarly journals Role of breast cancer resistance protein (BCRP/ABCG2) in cancer drug resistance

2012 ◽  
Vol 83 (8) ◽  
pp. 1084-1103 ◽  
Author(s):  
Karthika Natarajan ◽  
Yi Xie ◽  
Maria R. Baer ◽  
Douglas D. Ross
Keyword(s):  
Breast Cancer ◽  
Drug Resistance ◽  
Breast Cancer Resistance Protein ◽  
Cancer Drug ◽  
Cancer Resistance ◽  
Cancer Drug Resistance ◽  
Resistance Protein

scholarly journals The role of photodynamic therapy in overcoming cancer drug resistance

2015 ◽  
Vol 14 (8) ◽  
pp. 1476-1491 ◽  
Author(s):  
Bryan Q. Spring ◽  
Imran Rizvi ◽  
Nan Xu ◽  
Tayyaba Hasan
Keyword(s):  
Drug Resistance ◽  
Photodynamic Therapy ◽  
Cancer Cells ◽  
Cancer Drug ◽  
Cancer Drug Resistance

This perspective highlights unique mechanisms of photodynamic therapy (PDT) that can be utilized to overcome classical drug resistance and re-sensitize resistant cancer cells for standard therapies.

The role of aldehyde dehydrogenase (ALDH) in cancer drug resistance

2013 ◽  
Vol 67 (7) ◽  
pp. 669-680 ◽  
Author(s):  
Radosław Januchowski ◽  
Karolina Wojtowicz ◽  
Maciej Zabel
Keyword(s):  
Drug Resistance ◽  
Aldehyde Dehydrogenase ◽  
Cancer Drug ◽  
Cancer Drug Resistance

Cancer drug resistance: The central role of the karyotype☆

2007 ◽  
Vol 10 (1-2) ◽  
pp. 51-58 ◽  
Author(s):  
P DUESBERG ◽  
R LI ◽  
R SACHS ◽  
A FABARIUS ◽  
M UPENDER ◽  
...  
Keyword(s):  
Drug Resistance ◽  
Cancer Drug ◽  
Cancer Drug Resistance

The role of deubiquitinating enzymes in cancer drug resistance

2020 ◽  
Vol 85 (4) ◽  
pp. 627-639
Author(s):  
Parthasaradhireddy Tanguturi ◽  
Kye-Seong Kim ◽  
Suresh Ramakrishna
Keyword(s):  
Drug Resistance ◽  
Cancer Drug ◽  
Deubiquitinating Enzymes ◽  
Cancer Drug Resistance

scholarly journals Novel Implications of MicroRNAs, Long Non-coding RNAs and Circular RNAs in Drug Resistance of Esophageal Cancer

2021 ◽  
Vol 9 ◽  
Author(s):  
Ling Wei ◽  
Jujie Sun ◽  
Nasha Zhang ◽  
Yue Shen ◽  
Teng Wang ◽  
...  
Keyword(s):  
Drug Resistance ◽  
Esophageal Cancer ◽  
Checkpoint Inhibitors ◽  
Cancer Drug ◽  
Circular Rnas ◽  
Cancer Drug Resistance ◽  
Novel Biomarkers ◽  
Non Coding Rnas ◽  
Underlying Mechanisms ◽  
Poor Outcomes

Esophageal cancer is the eighth most common malignancy and the sixth leading cause of cancer-related deaths worldwide. Chemotherapy based on platinum drugs, 5-fluorouracil, adriamycin, paclitaxel, gemcitabine, and vinorelbine, as well as targeted treatment and immunotherapy with immune checkpoint inhibitors improved the prognosis in a portion of patients with advanced esophageal cancer. Unfortunately, a number of esophageal cancer patients develop drug resistance, resulting in poor outcomes. Multiple mechanisms contributing to drug resistance of esophageal cancer have been reported. Notably, non-coding RNAs (ncRNAs), including microRNAs (miRNAs), long non-coding RNAs (lncRNAs) and circular RNAs (circRNAs), have been identified to play crucial roles in modulating esophageal cancer drug resistance. In the present review, we highlight the underlying mechanisms how miRNAs, lncRNAs, and circRNAs impact the drug resistance of esophageal cancer. Several miRNAs, lncRNAs, and circRNAs may have potential clinical implications as novel biomarkers and therapeutic targets for esophageal cancer.

scholarly journals The role of galectin-3 in cancer drug resistance

2007 ◽  
Vol 10 (3) ◽  
pp. 101-108 ◽  
Author(s):  
Tomoharu Fukumori ◽  
Hiro-omi Kanayama ◽  
Avraham Raz
Keyword(s):  
Drug Resistance ◽  
Cancer Drug ◽  
Cancer Drug Resistance ◽  
Galectin 3
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