scholarly journals Basophil activation test in allergic rhinitis. Authors' reply.

2016 ◽  
Vol 126 (11) ◽  
pp. 904-904
Author(s):  
Małgorzata Leśniak ◽  
Marcel Mazur ◽  
Ewa Czarnobilska
Keyword(s):  
Allergic Rhinitis ◽  
Basophil Activation Test ◽  
Basophil Activation ◽  
Activation Test

Role of the basophil activation test in the diagnosis of local allergic rhinitis

2013 ◽  
Vol 132 (4) ◽  
pp. 975-976.e5 ◽  
Author(s):  
Enrique Gómez ◽  
Paloma Campo ◽  
Carmen Rondón ◽  
Esther Barrionuevo ◽  
Natalia Blanca-López ◽  
...  
Keyword(s):  
Allergic Rhinitis ◽  
Basophil Activation Test ◽  
Basophil Activation ◽  
Activation Test ◽  
Local Allergic Rhinitis

Role Of Basophil Activation Test For Identifying Subjects With Local Allergic Rhinitis

2014 ◽  
Vol 133 (2) ◽  
pp. AB75
Author(s):  
Paloma Campo ◽  
Carmen Rondon ◽  
Enrique Gómez ◽  
Esther Barrionuevo Sanchez ◽  
Luisa Galindo ◽  
...  
Keyword(s):  
Allergic Rhinitis ◽  
Basophil Activation Test ◽  
Basophil Activation ◽  
Activation Test ◽  
Local Allergic Rhinitis

Dynamics of basophil reactivity in the patients with allergic rhinitis on the background of allergen-specific immunotherapy

2021 ◽  
Vol 17 (4) ◽  
pp. 75-84
Author(s):  
Liudmila Yu. Barycheva ◽  
Liudmila V Dushina ◽  
Marina V. Golubeva ◽  
Milana M. Minasyan ◽  
Yulia N. Medvedenko
Keyword(s):  
Allergic Rhinitis ◽  
Specific Immunotherapy ◽  
Clinical Symptoms ◽  
Stimulation Index ◽  
Basophil Activation Test ◽  
Basophil Activation ◽  
House Dust Mites ◽  
Allergen Specific Immunotherapy ◽  
Activation Test ◽  
Positive Treatment

BACKGROUND: Allergen-specific immunotherapy (ASIT) helps to reduce spontaneous and to induce basophil reactivity, which is one of the major mechanisms of its effectiveness. A number of studies, though, have not confirmed the informative value of the basophil activation test (BAT), in case of ASIT, with house dust mites, meadow grass pollen, and wasp venom. BAT outcomes are likely to be influenced by the properties of the sensitizing allergen, the duration of ASIT, and the BAT markers that are used. AIMS: To evaluate the basophils reactivity in the patients sensitized to weed pollen and treated with allergen-specific therapy. MATERIALS AND METHODS: The study involved 60 patients (aged 1655) with allergic rhinitis sensitized to weed pollen. The diagnosis was based on the skin test outcomes as well as on identifying specific antibodies to major allergens of ragweed, wormwood, timothy, and birch. The pre-seasonal ASIT involved water-salted extracts of pollen allergens during 2 years. Clinical symptoms and the immunotherapy effectiveness were evaluated 6 and 18 months after the ASIT started. BATs were made before the treatment, after the first and second courses of pre-seasonal ASIT, which corresponded to zero, the 3rd and the 15th months of the treatment. The activated basophils were identified based on the CRTH2pos CD203brightCD3neg phenotype. RESULTS: The first treatment course was completed by 52 patients, while the second one by 43 patients. A statistically significant decrease in spontaneous basophil reactivity was detected only after the second course of ASIT. The decrease in the allergen-induced basophil activation was identified in 67.4% of the samples obtained after the first ASIT course, and in 67.6% of samples taken after the second immunotherapy course. A decrease in the BAT stimulation index (BAT SI) was identified mainly in the patients featuring positive treatment outcomes. CONCLUSIONS: ASIT influences on the basophil reactivity indicators in the patients sensitized to weed pollen. The basophil activation test may be considered as a potential predictor of ASIT effectiveness.

scholarly journals Subjects with local allergic rhinitis can be identified by basophil activation test

2013 ◽  
Vol 3 (S2) ◽  
Author(s):  
Paloma Campo ◽  
Carmen Rondon ◽  
Enrique Gomez ◽  
Natalia Blanca-Lopez ◽  
M Jose Torres ◽  
...  
Keyword(s):  
Allergic Rhinitis ◽  
Basophil Activation Test ◽  
Basophil Activation ◽  
Activation Test ◽  
Local Allergic Rhinitis

Basophil activation test for inhalant allergens in pediatric patients with allergic rhinitis

2017 ◽  
Vol 97 ◽  
pp. 197-201 ◽  
Author(s):  
Ismail Ogulur ◽  
Ayca Kiykim ◽  
Safa Baris ◽  
Ahmet Ozen ◽  
Ezgi Gizem Yuce ◽  
...  
Keyword(s):  
Allergic Rhinitis ◽  
Pediatric Patients ◽  
Basophil Activation Test ◽  
Basophil Activation ◽  
Activation Test ◽  
Inhalant Allergens

Usefulness of basophil activation test for the diagnosis of peanut allergy in Japanese children

2014 ◽  
Vol 28 (2) ◽  
pp. 216-225
Author(s):  
Shigeyuki Narabayashi ◽  
Takaaki Meguro ◽  
Yasunori Ito ◽  
Fumika Tokunaga ◽  
Shiro Seto ◽  
...  
Keyword(s):  
Peanut Allergy ◽  
Basophil Activation Test ◽  
Basophil Activation ◽  
Japanese Children ◽  
Activation Test
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