scholarly journals The ISCHEMIA trial: nothing is complete unless put in final shape

2021 ◽  
Vol 131 (11) ◽  
Author(s):  
Sang‑Wook Kim ◽  
Jun Hwan Cho ◽  
Hoyoun Won
Keyword(s):  
Final Shape

Contemporary Methods of Designing Rail Vehicle Running Systems with the Use of CAD and CAM Solutions

2020 ◽  
Vol 64 (187) ◽  
pp. 75-80
Author(s):  
Tomasz Antkowiak ◽  
Marcin Kruś
Keyword(s):  
System Design ◽  
Preliminary Design ◽  
Support Design ◽  
Detailed Design ◽  
Final Shape ◽  
Rail Vehicle ◽  
Design Engineers ◽  
Running System ◽  
Cad Cam

The article discusses the process of designing the running system of a rail vehicle using CAD and CAM tools as the solutions supporting the process. It describes the particular stages of design taking its final shape: from a preliminary design, through a detailed design, ending with the stage of production. Each stage includes a presentation of how CAD and CAM tools are used to support design engineers in their practice. Keywords: running system, design, CAD, CAM

Oklahoma!

2020 ◽  
Author(s):  
Tim Carter
Keyword(s):  
Musical Theater ◽  
Final Shape ◽  
Broadway Musical ◽  
History Of ◽  
Rodgers And Hammerstein ◽  
Theatre Guild

Oklahoma! premiered on Broadway on 31 March 1943 under the auspices of the Theatre Guild, and today it is performed more frequently than any other Rodgers and Hammerstein musical. When this book was first published in 2007, it offered the first fully documented history of the making of the show based on archival materials, manuscripts, journalism, and other sources. The present revised edition draws still further on newly uncovered sources to provide an even clearer account of a work that many have claimed fundamentally changed Broadway musical theater. It is filled with rich and fascinating details about the play on which Oklahoma! was based (Lynn Riggs’s Green Grow the Lilacs); on what encouraged Theresa Helburn and Lawrence Langner of the Guild to bring Rodgers and Hammerstein together for their first collaboration; on how Rouben Mamoulian and Agnes de Mille became the director and choreographer; on the drafts and revisions that led the show toward its final shape; and on the rehearsals and tryouts that brought it to fruition. It also examines the lofty aspirations and the mythmaking that surrounded Oklahoma! from its very inception, and demonstrates just what made it part of its times.

Final shape of biovascular scaffolds and clinical outcome. Results from a multicenter all-comers study with intravascular imaging

2017 ◽  
Vol 228 ◽  
pp. 209-213 ◽  
Author(s):  
Bernardo Cortese ◽  
Davide Piraino ◽  
Roberto A. Latini ◽  
Dennis Zavalloni ◽  
Alfonso Ielasi ◽  
...  
Keyword(s):  
Clinical Outcome ◽  
Intravascular Imaging ◽  
Final Shape

Mechanism of pellet egestion in great-horned owls (Bubo virginianus)

1976 ◽  
Vol 231 (6) ◽  
pp. 1824-1829 ◽  
Author(s):  
GE Duke ◽  
OA Evanson ◽  
PT Redig ◽  
DD Rhoades
Keyword(s):  
Gastrointestinal Motility ◽  
Strain Gauge ◽  
Abdominal Muscles ◽  
Lower Esophagus ◽  
Bubo Virginianus ◽  
Final Shape ◽  
Bipolar Electrodes ◽  
Gastric Contractions

To study the mechanism of oral pellet egestion in great-horned owls, bipolar electrodes and strain-gauge transducers were chronically implanted in the esophagus, muscular stomach, and duodenum of six owls. Recordings from conscious owls plus simultaneous radiographic observations revealed characteristic gastrointestinal motility patterns associated with egestion. Beginning at about 12 min before egestion, gastric contractions formed the final shape of the pellet and pushed it into the lower esophagus. The pellet was moved out of the esophagus by antiperistalsis during the last 8--10 s before egestion. During pellet egestion, contractions of abdominal muscles were not detected. Pellet egestion appears to be unlike either emesis in mammals with a simple stomach or regurgitation in ruminants.

Competence and lithostratigraphy of host rocks govern kimberlite pipe morphology

2018 ◽  
Vol 55 (2) ◽  
pp. 130-137
Author(s):  
David E. Newton ◽  
Amy G. Ryan ◽  
Luke J. Hilchie
Keyword(s):  
Host Rock ◽  
Sedimentary Rock ◽  
Kimberlite Pipe ◽  
Crystalline Rock ◽  
Experimental Results ◽  
Compressed Air ◽  
Unconsolidated Sediments ◽  
Final Shape ◽  
Class 1 ◽  
Host Rocks

We use analogue experimentation to test the hypothesis that host rock competence primarily determines the morphology of kimberlite pipes. Natural occurrences of kimberlite pipes are subdivided into three classes: class 1 pipes are steep-sided diatremes emplaced into crystalline rock; class 2 pipes have a wide, shallow crater emplaced into sedimentary rock overlain by unconsolidated sediments; class 3 pipes comprise a steep-sided diatreme with a shallow-angled crater emplaced into competent crystalline rock overlain by unconsolidated sediments. We use different configurations of three analogue materials with varying cohesions to model the contrasting geological settings observed in nature. Pulses of compressed air, representing the energy of the gas-rich head of a kimberlitic magma, are used to disrupt the experimental substrate. In our experiments, the competence and configuration of the analogue materials control the excavation processes as well as the final shape of the analogue pipes: eruption through competent analogue strata results in steep-sided analogue pipes; eruption through weak analogue strata results in wide, shallow analogue pipes; eruption through intermediate strength analogue strata results in analogue pipes with a shallow crater and a steep-sided diatreme. These experimental results correspond with the shapes of natural kimberlite pipes, and demonstrate that variations in the lithology of the host rock are sufficient to generate classic kimberlite pipe shapes. These findings are consistent with models that ascribe the pipe morphologies of natural kimberlites to the competence of the host rocks in which they are emplaced.

scholarly journals Stochastic Modal Models of Slender Uncertain Curved Beams Preloaded Through Clamping

2012 ◽  
Author(s):  
Javier Avalos ◽  
Lanae A. Richter ◽  
X. Q. Wang ◽  
Raghavendra Murthy ◽  
Marc P. Mignolet
Keyword(s):  
Stochastic Model ◽  
Stiffness Matrix ◽  
Natural Frequencies ◽  
Simulated Data ◽  
Mode Shapes ◽  
Curved Beams ◽  
Shape Information ◽  
Final Shape ◽  
Modal Model ◽  
Clamped Beams

This paper addresses the stochastic modeling of the stiffness matrix of slender uncertain curved beams that are forced fit into a clamped-clamped fixture designed for straight beams. Because of the misfit with the clamps, the final shape of the clamped-clamped beams is not straight and they are subjected to an axial preload. Both of these features are uncertain given the uncertainty on the initial, undeformed shape of the beams and affect significantly the stiffness matrix associated with small motions around the clamped-clamped configuration. A modal model using linear modes of the straight clamped-clamped beam with a randomized stiffness matrix is employed to characterize the linear dynamic behavior of the uncertain beams. This stiffness matrix is modeled using a mixed nonparametric-parametric stochastic model in which the nonparametric (maximum entropy) component is used to model the uncertainty in final shape while the preload is explicitly, parametrically included in the stiffness matrix representation. Finally, a maximum likelihood framework is proposed for the identification of the parameters associated with the uncertainty level and the mean model, or part thereof, using either natural frequencies only or natural frequencies and mode shape information of the beams around their final clamped-clamped state. To validate these concepts, a simulated, computational experiment was conducted within Nastran to produce a population of natural frequencies and mode shapes of uncertain slender curved beams after clamping. The application of the above concepts to this simulated data led to a very good to excellent matching of the probability density functions of the natural frequencies and the modal components, even though this information was not used in the identification process. These results strongly suggest the applicability of the proposed stochastic model.

scholarly journals Military Themes in Selected Eighteenth-Century Prayer Books in Relation to the Emblem Tradition

Terminus ◽  
2019 ◽  
Vol 21 (Special Issue 1) ◽  
pp. 107-138
Author(s):  
Iwona Słomak
Keyword(s):  
Eighteenth Century ◽  
Religious Literature ◽  
Final Shape ◽  
Prayer Books

This paper was inspired by the lack of studies that would show examples of military-erotic symbols in religious literature associated with the emblem tradition. The works discussed here, namely prayer books by Andrzej Gabriel Kasperowicz, anonymous Atak niebieskiej twierdzy [The attack of the heavens or The attack into the fortress of heavens] and Wojsko serdecznych afektów [The army of heartfelt affections] by Hieronim Falęcki, retain high formal and semantic discipline; as a result, they are examples of interesting phenomena of Baroque culture. In the first part of the study, Słomak presents three prayer books in which the concept is based on an analogy with the organisation of the army of Christ. In the second part, she presents a book in which the theme of war is combined with the theme of “holy erotica”. In part three, she discusses a print whose composition refers to the structure of military detachments. It is conceived as a collection of “affections” whose task is “to conquer” heaven and the hearts of readers. Characteristically, the formula of the discussed books will be understandable only if we reconstruct their reference to the popular allegorical images (to be found in the collections of emblems, in many treatises on religious themes or in descriptions of the great ceremonies of that era); therefore, it is necessary to take into account the emblematic model that clearly influenced their final shape.

Henry VIII's wills: a comment

1994 ◽  
Vol 37 (4) ◽  
pp. 891-899 ◽  
Author(s):  
R. A. Houlbrooke
Keyword(s):  
Final Shape ◽  
The Will

ABSTRACTProfessor Ives has demonstrated the weakness of some of the grounds for thinking that Henry VIII's will was tampered with after 30 December 1546. But he has not mentioned Paget's later testimony suggesting that the ‘unfulfilled gifts clause’ was inserted in the will after 12 January 1547. Even if it was part of the will by 30 December, the gifts implemented by its authority resulted from later skilful and ruthless manipulation of the king. Henry's ‘unwritten will’ greatly strengthened Edward Seymour and his allies and gave William Paget, who was largely responsible for its final shape, the means of buying off potential objectors to Seymour's elevation to the protectorship.

Organ shape in the Drosophila salivary gland is controlled by regulated, sequential internalization of the primordia

Development ◽  
2000 ◽  
Vol 127 (4) ◽  
pp. 679-691 ◽  
Author(s):  
M.M. Myat ◽  
D.J. Andrew
Keyword(s):  
Salivary Gland ◽  
Cell Shape ◽  
Cell Adhesion Molecule ◽  
Scanning Electron Micrographs ◽  
Final Shape ◽  
A Cell ◽  
Gland Development ◽  
Aberrant Tubes ◽  
Shape Changes ◽  
Multiple Stages

During Drosophila development, the salivary primordia are internalized to form the salivary gland tubes. By analyzing immuno-stained histological sections and scanning electron micrographs of multiple stages of salivary gland development, we show that internalization occurs in a defined series of steps, involves coordinated cell shape changes and begins with the dorsal-posterior cells of the primordia. The ordered pattern of internalization is critical for the final shape of the salivary gland. In embryos mutant for huckebein (hkb), which encodes a transcription factor, or faint sausage (fas), which encodes a cell adhesion molecule, internalization begins in the center of the primordia, and completely aberrant tubes are formed. The sequential expression of hkb in selected cells of the primordia presages the sequence of cell movements. We propose that hkb dictates the initial site of internalization, the order in which invagination progresses and, consequently, the final shape of the organ. We propose that fas is required for hkb-dependent signaling events that coordinate internalization.

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