scholarly journals Antiplatelet effects of micronized fenofibrate in subjects with dyslipidemia

2007 ◽  
Vol 117 (5-6) ◽  
pp. 235-240
Author(s):  
Anetta Undas ◽  
Magdalena Celińska-Löwenhoff
Keyword(s):  
Micronized Fenofibrate

The Effect of Micronized Fenofibrate on Lipid Profiles of Patients Converted from Gemfibrozil

2002 ◽  
Vol 37 (9) ◽  
pp. 953-956 ◽  
Author(s):  
Jim M. Backes ◽  
Patrick M. Moriarty ◽  
Cheryl A. Gibson
Keyword(s):  
Randomized Trial ◽  
Lipid Profile ◽  
Lipid Profiles ◽  
Comparative Data ◽  
Lipid Lowering ◽  
Lipid Lowering Therapy ◽  
Two Agents ◽  
Lowering Therapy ◽  
Micronized Fenofibrate ◽  
The Mean

Although numerous studies have established the efficacy of micronized fenofibrate (MF) and gemfibrozil in improving lipid profiles, there are limited comparative data on the lipid-lowering effects of these two agents. The objective of this study was to evaluate the mean changes in lipid values of hypertriglyceridemic patients crossed over from gemfibrozil to MF. The Medical charts of 21 patients were analyzed retrospectively. Patients were maintained on gemfibrozil 600 mg twice daily for a minimum of 3 months. The patient's last fasting lipid profile on gemfibrozil was compared to the first lipid profile after crossover to MF 200 to 201 mg/day. Patients were excluded if there were alterations in other lipid-lowering therapy during the cross-over or documented non-adherence. The lipid profiles after the crossover showed a significant reduction in triglycerides (56%; P < 0.05) and TC/HDL ratio (38%; P < 0.05) and a significant increase in HDL (22%; P < 0.05). There were nonsignificant changes in other lipid values: TC (-22%; P = 0.058), LDL (+5%; P = 0.866) and LDL/HDL ratio (+6; P = 1.0). The results show that MF had additional favorable effects on triglycerides, HDL, and TC/HDL ratio compared with gemfibrozil. A larger, randomized trial to confirm these effects is warranted.

A multicenter comparison of micronized fenofibrate and simvastatin in patients with primary type IIa or IIb hyperlipoproteinemia

1994 ◽  
Vol 109 (1-2) ◽  
pp. 157-158
Author(s):  
A. Steinmetz ◽  
J.R. Scha¨fer ◽  
H. Kaffarnik ◽  
T. Schwartz
Keyword(s):  
Micronized Fenofibrate ◽  
Primary Type

Micronized fenofibrate in the management of dyslipidemia

Diabetes Care ◽  
1998 ◽  
Vol 21 (11) ◽  
pp. 2039-2040
Author(s):  
G. Steiner
Keyword(s):  
Micronized Fenofibrate

Comparison of the Efficacy of Atorvastatin and Micronized Fenofibrate in the Treatment of Mixed Hyperlipidemia

1999 ◽  
Vol 6 (2) ◽  
pp. 113-116 ◽  
Author(s):  
Eleni T. Bairaktari ◽  
Christos S. Tzallas ◽  
Vassilios K. Tsimihodimos ◽  
Evangelos N. Liberopoulos ◽  
George A. Miltiadous ◽  
...  
Keyword(s):  
Micronized Fenofibrate ◽  
Mixed Hyperlipidemia
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