scholarly journals Hepatic Angiosarcoma Masquerading as Hemangioma: A Challenging Differential Diagnosis

2017 ◽  
Vol 30 (10) ◽  
pp. 750
Author(s):  
Ana Rita Garcia ◽  
João Ribeiro ◽  
Helena Gervásio ◽  
Francisco Castro e Sousa
Keyword(s):  
Computed Tomography ◽  
Malignant Tumors ◽  
Palliative Radiotherapy ◽  
Abdominal Ultrasound ◽  
Gamma Glutamyl Transferase ◽  
Computed Tomography Scan ◽  
Hepatic Angiosarcoma ◽  
Imaging Characteristics ◽  
Glutamyl Transferase ◽  
Tomography Scan

Hemangiomas are usually diagnosed based on ultrasound findings. The presence of symptoms, rapid growth or atipical imagiological findings should make us consider other diagnoses, including malignant tumors such as angiosarcomas. We describe the case of a previously healthy 46-year-old female without a history of exposure to carcinogens who presented with abdominal pain for two months. Diagnostic work-up revealed elevated gamma-glutamyl transferase and lactate dehydrogenase levels. Abdominal ultrasound described a large nodular lesion in the right lobe of the liver described as a hemangioma. One month later, a computed tomography-scan was made and revealed the same lesion, which had grown from 13.5 to 20 cm, maintaining typical imaging characteristics of a hemangioma. A right hepatectomy was performed and pathology revealed an angiosarcoma. After surgery, a positron emission tomography-computed tomography scan showed hepatic and bone metastasis. The patient started taxane-based chemotherapy and lumbar palliative radiotherapy, but died 10 months after surgery. This case shows how difficult it is to diagnose hepatic angiosarcoma relying only on imaging findings. Two abdominal computed tomography -scans were performed and none suggested this diagnosis. Angiosarcoma is a very aggressive tumour with an adverse prognosis. Surgery is the only curative treatment available. However, it is rarely feasible due to unresectable disease or distant metastasis.

Hepatitis following Treatments with Famotidine and Then CimetIDINE

1994 ◽  
Vol 28 (1) ◽  
pp. 37-39 ◽  
Author(s):  
Fred Hashimoto ◽  
Robin L. Davis ◽  
Douglas Egli
Keyword(s):  
Computed Tomography ◽  
Duodenal Ulcer ◽  
Fatty Liver ◽  
Obese Woman ◽  
Abdominal Ultrasound ◽  
Drug Discontinuation ◽  
Computed Tomography Scan ◽  
Case Summary ◽  
Receptor Blockers ◽  
Tomography Scan

OBJECTIVE: To report a case of hepatitis induced by two histamine (H2)-receptor blockers, famotidine and cimetidine. CASE SUMMARY: A 51-year-old obese woman with a duodenal ulcer developed symptomatic, famotidine-induced hepatitis. Other causes for hepatitis were ruled out. Famotidine was discontinued and the patient took omeprazole for a month without incident. Cimetidine therapy was then initiated and shortly thereafter, the patient developed another episode of symptomatic hepatitis that resolved upon drug discontinuation. Two abdominal ultrasound examinations six months apart and an abdominal computed tomography scan obtained later showed what appeared to be a stable, fatty liver. DISCUSSION: This appears to be the first reported case of clinical hepatitis related to famotidine and the first reported case where clinical hepatitis followed the administration of two different H2-receptor blockers. The fatty liver probably was secondary to obesity and incidental to the hepatitis episodes. CONCLUSIONS: Famotidine can cause clinical hepatitis, and druginduced hepatitis can occur after the administration of two different H2-receptor blockers.

scholarly journals Volvulus of ileum: A rare case of small bowel obstruction and the effectiveness of abdominal ultrasound imaging for the diagnosis

2019 ◽  
Vol 15 (2) ◽  
Author(s):  
Bajhat Barakat ◽  
Raffaele Pezzilli
Keyword(s):  
Computed Tomography ◽  
Small Bowel ◽  
Imaging Modality ◽  
Abdominal Ultrasound ◽  
Computed Tomography Scan ◽  
Mesenteric Lymph Nodes ◽  
Abdominal Ultrasonography ◽  
Primary Type ◽  
Tomography Scan ◽  
Secondary Type

Primary type small bowel volvulus is observed mainly in children and young adults, whereas the secondary type is usually found between the ages of 40 and 90 years and is mainly due to adhesions after previous surgery: tumors and mesenteric lymph nodes can also be responsible for the secondary type. Diagnosis is difficult and the computed tomography scan is the most relevant imaging modality. For this reason we believe that the case presented in which diagnosis was primary made by abdominal ultrasonography and then confirmed first by computed tomography scan and definitively by surgical exploration is worth reporting.

scholarly journals GAMBARAN CT SCAN TUMOR PARU DI BAGIAN / SMF RADIOLOGI FK UNSRAT RSUP PROF. DR. R. D. KANDOU MANADO PERIODE OKTOBER 2014-SEPTEMBER 2015

e-CliniC ◽  
2016 ◽  
Vol 4 (1) ◽  
Author(s):  
Meidianty Tandi ◽  
Vonny N. Tubagus ◽  
Martin L. Simanjuntak
Keyword(s):  
Computed Tomography ◽  
Ct Scan ◽  
Lung Tumor ◽  
Malignant Tumors ◽  
Smoking Habit ◽  
The Body ◽  
Epithelial Tissue ◽  
Computed Tomography Scan ◽  
The Right ◽  
Tomography Scan

Abstract: Lung tumor has become one of the most common tumors in the world. Lung tumor is the growth of abnormal lumps on lung tissue that could be benign or malignant, derived from malignant tumors of primary epithelial tissue in respiratory tract especially bronchus that could invade nearby tissue structures, and potentially spread throughout the body by bloodstream and lymphatic system. Approximately 1.59 billion people worldwide died from lung malignancy resulting from the increasing of smoking habit which is one of the risk factors of lung tumor. CT scan is the chosen modality on diagnosing the suspicion of lung tumor and also to evaluate the tumor itself. The aim of this study is to identify the CT scan images on patients with lung tumor. Retrospective descriptive study was conducted on November 2015. The data was obtained from thorax CT scan examination request forms and eventually 41 cases of lung tumor were found eligible according to inclusion criteria. Based on radiologic diagnosis there were 41 cases (39,4%) of lung tumor. The patients were mostly male with 35 patients (85.4%), the largest age group is middle aged adults with 30 patients (73.2%), and the most common site of tumor was the right lung with 22 cases (53.7%), moreover the most complication of lung tumor is pleural effusion with 13 cases (31.7%). Conclusion: Lung tumor is one of malignancies that become risk factor of deaths worldwide.Keywords: lung tumor, computed tomography scan. Abstrak: Tumor paru menjadi salah satu tumor yang paling banyak ditemui di dunia. Tumor paru adalah tumbuhnya benjolan abnormal pada jaringan paru yang dapat bersifat jinak atau ganas, serta berasal dari tumor ganas epitel primer saluran nafas terutama bronkus yang dapat menginvasi struktur jaringan disekitarnya dan berpotensi menyebar ke seluruh tubuh melalui aliran darah dan sistem limfatik. Terdapat sekitar 1,59 miliar orang di dunia meninggal dunia akibat keganasan pada paru-paru karena tingginya kebiasaan merokok yang merupakan salah satu faktor resiko terjadinya tumor pada paru. CT scan menjadi modalitas terpilih untuk menegakkan diagnosis kecurigaan tumor paru dan untuk mengevaluasi tumor paru tersebut. Penelitian ini bertujuan untuk mengetahui gambaran CT scan pada penderita tumor paru dan menggunakan jenis penelitian deskriptif retropektif yang dilakukan pada bulan November 2015. Data diperoleh melalui lembaran permintaan pemeriksaan CT scan toraks dan didapatkan sebanyak 41 kasus tumor paru yang masuk dalam kriteria inklusi.Terdapat 41 kasus (39,4 %) tumor paru berdasarkan diagnosis radiologis. Penderita terbanyak adalah laki-laki 35 orang (85,4%), golongan umur terbanyak adalah umur 41-65 tahun yaitu 30 orang (73,2%), lokasi tumor paru terbanyak pada pulmo dextra yaitu 22 kasus (53,7%) dan komplikasi terbanyak adalah tumor paru dengan efusi pleura saja sebanyak 13 kasus (31,7%). Simpulan: Tumor paru merupakan salah satu penyakit keganasan yang menjadi faktor resiko kematian di seluruh dunia.Kata kunci: tumor paru, computed tomography scan.

scholarly journals Sitagliptin-induced Pancreatitis: A case report and plausible mechanism

2021 ◽  
Vol 11 (3) ◽  
pp. 1-3
Author(s):  
Kamel El-Reshaid ◽  
Shaikha Al-Bader ◽  
Zaneta Markova
Keyword(s):  
Diabetes Mellitus ◽  
Computed Tomography ◽  
Epigastric Pain ◽  
Abdominal Ultrasound ◽  
Biliary Duct ◽  
Computed Tomography Scan ◽  
Drug Induced ◽  
Pain Medications ◽  
Plausible Mechanism ◽  
Tomography Scan

Drugs are rare cause of acute pancreatitis (AP) with an estimate incidence of 0.1-2%. We present an 63-year-man 1 week history of severe and progressive epigastric pain that radiates to the back and is worse on lying down, who was found to have lipase of more than 813 IU/L. The patient denied current alcohol use. Abdominal ultrasound and abdominal computed tomography scan did not show gallstones or biliary duct abnormalities. For his type-2 diabetes mellitus, he was taking Gliclazide and Metformin for years and Sitagliptin was the only drug added 6 months ago. He was managed conservatively with intravenous fluids, pain medications, and control of diabetes with insulin.  Within 3 days, he improved dramatically and was discharged on diabetic diet and Gliclazide 120 mg daily with Lantos 10 units at night.  He was instructed to avoid oral hypoglycemia agents from the dipeptidyl-peptidase IV inhibitors (DPP-4i) group.  Three weeks later, repeat computed tomography scan of the abdomen showed normal pancreas.  On follow up; and up to 1 year, he did not have subsequent AP.  The most plausible mechanism of such late-development of rare drug-induced AP is late-encounter with triggering factor/s for Sitagliptin in genetically-predisposed individuals.    Keywords: CT scan, diabetes mellitus, DPP-4i, metformin, pancreatitis, Sitagliptin.

scholarly journals A Rare Case of Primary Hepatic Adenosquamous Carcinoma Mimicking Liver Abscess

2021 ◽  
Vol 2 (2) ◽  
pp. 52-53
Author(s):  
Wei Liu
Keyword(s):  
Computed Tomography ◽  
Weight Loss ◽  
Liver Abscess ◽  
Adenosquamous Carcinoma ◽  
Clinical Manifestations ◽  
Gamma Glutamyl Transferase ◽  
Fungal Culture ◽  
Imaging Characteristics ◽  
Glutamyl Transferase ◽  
Purulent Fluid

A 61-year-old woman with a 3-week history of chills, fevers to 39°C, anorexia, weight loss, and fatigue was referred to our hospital due to the progressive discomforts over the last week. Her documented medical history was notable for well-controlled type 2 diabetes. Physical examination was unremarkable. Notable laboratory tests of the blood revealed a hemoglobin level of 90 g/L, a white blood cell count of 11.7×109/L with neutrophil 90.7%, albumin 31.6 g/L, gamma glutamyl transferase 331 IU/L, alkaline phosphatase 748 IU/L. Direct microbiologic detection and cultures were negative for hepatitis B and C virus, bacterial and fungal pathogens, and human immunodeficiency virus. A computed tomography scan of the chest was unremarkable. Abdominal contrast-enhanced computed tomography discovered an ill-defined and sub-circular lowdensity region measuring 7.6×6.1cm with patchy enhancement in the right lobe of liver (Figure A), which implied a liver abscess. Empiric antibiotics were changed to meropenem combined with metronidazole on day three of hospitalisation. However, the fever did not alleviate with poorly therapeutic effect. Ultrasound-guided biopsy was performed and purulent fluid was collected to make a definitive diagnosis of the liver mass. Surprisingly, The histopathological detection of a needle biopsy sample confirmed neoplastic necrosis with negative bacterial and fungal culture of the purulent fluid. The patient then underwent right hemihepatectomy and histopathologic examination further revealed that the lesion included a mixture of a poorly differentiated adenocarcinoma with mucin production and squamous cell carcinoma with keratinization, as well as large patchy necrosis (Figure B). On immunostaining, the lesion stained strongly with CK5/6, P63, and P40, and was also partially positive for CK7, CK8/18, and Cam5.2 with negative staining for hepatocyte and alpha-fetoprotein, which were consistent with adenosquamous carcinoma of the liver. Primary hepatic adenosquamous carcinoma is a rare variant of intrahepatic cholangiocarcinoma with approximately 10 cases reported within 5 years.1,2 The pathogenesis of adenosquamous carcinoma of the liver is largely unknown owing to limited data in the literature. Fever, jaundice, weight loss, anorexia, and abdominal pain are the most frequently reported clinical manifestations.3 Adenosquamous carcinoma of the liver usually presents atypical imaging characteristics, which is difficult to distinguish it from liver abscess, hepatocellular carcinoma, and liver metastasis. Adenosquamous carcinoma of the liver is a highly aggressive neoplasm and the median survival time is 6 months after surgery.4 Therefore, preoperative diagnosis is of vital importance to predict a poor prognosis. Despite postoperative chemoradiation, the patient passed away 7 months after surgery.

scholarly journals Multiple Tracheal Diverticula in a COVID-19 Positive Patient

2021 ◽  
pp. 014556132110346
Author(s):  
Konstantinos Garefis ◽  
Konstantinos Tarazis ◽  
Konstantinos Gkiouzelis ◽  
Anastasia Kipriotou ◽  
Iordanis Konstantinidis ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Incidental Finding ◽  
Positive Patient ◽  
Computed Tomography Scan ◽  
Tracheal Diverticulum ◽  
Tomography Scan ◽  
Paratracheal Air Cyst

A tracheal diverticulum is a type of paratracheal air cyst and is usually an incidental finding after a computed tomography scan of the neck and thorax. With an incidence between 1% and 4% in adults, tracheal diverticula are rare entities that can be symptomatic in certain cases. We present a case of a COVID-19 positive patient who presented to our hospital and was diagnosed with multiple tracheal diverticula during his hospitalization.

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