scholarly journals Whose Child is This? The Problem of Constructing and Deconstructing Kinship Bonds on the Donor Gamete Market

Inter ◽  
2020 ◽  
Vol 12 (4) ◽  
pp. 73-92
Author(s):  
Tatyana Yu. Larkina
Keyword(s):  
Assisted Reproductive Technologies ◽  
Subsequent Development ◽  
Reproductive Technologies ◽  
Human Reproduction ◽  
Sociological Research ◽  
Reproductive Choice ◽  
Surrogate Motherhood ◽  
Reproductive Process ◽  
Goods And Services ◽  
Gamete Donor

Invention and subsequent development of human reproduction technologies allow people to manage reproductive risks, overcome infertility and widen alternative reproductive choice. Medicine has given men and women the access to programmes of saving biogenetic material, DNA-tests for identifying paternity and services for creating a genetic passport which identifies potential diseases and genetic peculiarities. However, assisted reproductive technologies, such as donorship of sex sells and surrogate motherhood, are violating the familiar integrity of reproductive process and changing the usual perception of kinship as sharing of biological substance. A distinguishing feature of the market for gamete donation and surrogate motherhood lies in the importance of both construction and deconstruction of kinship between donors, recipients of reproductive goods and services and a baby, who is born with the help of the ART methods (assisted reproductive technologies).Basing on the results of sociological research of donor sex sells market, the author of the article shows us how members of reproductive business coordinate different parts of their work (technical, emotional, legal, financial etc.), in order to solve the controversial problem of defining kinship between the participants of the donor programmes. On the one hand, medical specialists and representatives of reproductive agencies take part in destroying the kinship between a gamete donor and a baby, and on the other hand, they participate in creating and supporting kin ties between parents received donor sex sells and a baby, who doesn’t have common gens with them. Empirical study base consists of expert interviews with the employees of medical clinics and reproductive agencies in Moscow and Saint Petersburg.

ON THE NEED FOR SOCIOLOGICAL RESEARCH ON THE INTRODUCTION OF ASSISTED REPRODUCTIVE TECHNOLOGIES IN BELARUS

2021 ◽  
Vol 19 (4) ◽  
pp. 451-456
Author(s):  
A. V. Salmina ◽  
Keyword(s):  
New England ◽  
Intracytoplasmic Sperm Injection ◽  
Assisted Reproductive Technologies ◽  
Social Trust ◽  
Reproductive Technologies ◽  
Sociological Research ◽  
Surrogate Motherhood ◽  
Sociological Study ◽  
Morphological Criteria ◽  
The Republic

Background. At present there are no scientifically substantiated data on the problems of introducing assisted reproductive technologies (ART) in the Republic of Belarus. The relevance of developing approaches, organizing opinion polls and processing data on a representative sample of Belarusians does not raise doubts in view of the relationship between social attitudes in the field of reproductive health and the national security of the country. Purpose. Substantiation of medical and sociological study of ART in the population of the Republic of Belarus. Material and methods. The bibliographic analysis included the study of Russian and foreign experience in assessing the sociological aspects of reproductology (materials of Springer Link, Oxford University Press, The New England Journal of Medicine, The British Medical Journal, the SCOPUS database of Elsevier, the EBSCO platform), as well as the analysis of the legislation of the Republic of Belarus in the field of reproductology. Results. In the country, the interests of the party that wants to become a parent (surrogate motherhood, donation) are respected as much as possible. The medicalized approach to the definition of ART methods in Belarus is typical, as in other post-Soviet countries, which are characterized by a classical (nuclear) understanding of the family. Taking into account the current trends in the development of the market for reproductive technologies and those techniques that are used in reproductive centers of the Republic of Belarus, it is necessary in the legislative framework to provide for the rules and possibilities of using such methods as hatching (dissection of the embryo membrane), intracytoplasmic sperm injection, intracytoplasmic sperm injection after selection according to morphological criteria, preimplantation diagnostics. Conclusions. The following areas are relevant for Belarus: 1) study of the awareness of the population of the Republic of Belarus about ART; 2) assessment of social trust in ART on the part of the population; 3) development of technologies for positive reproductive attitudes in society, including the use of ART.

scholarly journals Inositol and vitamin D may naturally protect human reproduction and women undergoing assisted reproduction from COVID-19 risk

2021 ◽  
pp. 113-117
Author(s):  
M.S. Bezerra Espinola ◽  
M. Bertelli ◽  
M. Bizzarri
Keyword(s):  
Vitamin D ◽  
Immune System ◽  
Pregnant Women ◽  
Assisted Reproductive Technologies ◽  
Respiratory Infections ◽  
Phosphatidyl Inositol ◽  
Reproductive Technologies ◽  
Human Reproduction ◽  
Risk Category ◽  
Virus Species

In late 2019, the new Coronavirus has been identified in the city of Wuhan (China) then COVID-19 spreads like wildfire in the rest of the world. Pregnant women represent a risk category for increased abortion rates and vertical transmission with adverse events on the newborns has been recently confirmed. The scientific world is struggling for finding an effective cure for counteracting symptomatology. Today, there are many therapeutic proposes but none of them can effectively counteract the infection. Moreover, many of these compounds show important side effects not justifying their use. Scientific literature reports an immune system over-reaction through interleukins- 6 activation. In this regard, the possibility to control the immune system represents a possible strategy for counteracting the onset of COVID-19 symptomatology. Vitamin D deficiency shows increased susceptibility to acute viral respiratory infections. Moreover, Vitamin D seems involved in host protection from different virus species by modulating activation and release of cytokines. Myo-inositol down-regulates the expression of IL-6 by phosphatidyl-inositol-3-kinase pathway. Furthermore, myo-inositol is the precursor of phospholipids in the surfactant and it is applied for inducing surfactant synthesis in infants for treating respiratory distress syndrome. This review aims to summarize the evidence about COVID-19 infection in pregnant women and to encourage the scientific community to investigate the use of Vitamin D and Myo-inositol which could represent a possible preventive treatment for pregnant women or women undergoing assisted reproductive technologies.

scholarly journals Microbiota and Human Reproduction: The Case of Female Infertility

2020 ◽  
Vol 9 (2) ◽  
pp. 12 ◽  
Author(s):  
Rossella Tomaiuolo ◽  
Iolanda Veneruso ◽  
Federica Cariati ◽  
Valeria D’Argenio
Keyword(s):  
Reproductive Tract ◽  
Assisted Reproductive Technologies ◽  
Embryo Implantation ◽  
Reproductive Technologies ◽  
Human Reproduction ◽  
Microbial Dysbiosis ◽  
Technical Issues ◽  
Almost All ◽  
Generation Sequencing

During the last decade, the availability of next-generation sequencing-based approaches has revealed the presence of microbial communities in almost all the human body, including the reproductive tract. As for other body sites, this resident microbiota has been involved in the maintenance of a healthy status. As a consequence, alterations due to internal or external factors may lead to microbial dysbiosis and to the development of pathologies. Female reproductive microbiota has also been suggested to affect infertility, and it may play a key role in the success of assisted reproductive technologies, such as embryo implantation and pregnancy care. While the vaginal microbiota is well described, the uterine microbiota is underexplored. This could be due to technical issues, as the uterus is a low biomass environment. Here, we review the state of the art regarding the role of the female reproductive system microbiota in women’s health and human reproduction, highlighting its contribution to infertility.

scholarly journals Assisted reproductive technologies: psychoneurological, moral-ethical, and socio-cultural aspects

2020 ◽  
Vol 12 (5) ◽  
pp. 104-110
Author(s):  
N. A. Tyuvina ◽  
A. O. Nikolaevskaya
Keyword(s):  
Assisted Reproductive Technologies ◽  
Reproductive Technologies ◽  
Surrogate Mother ◽  
Reproductive Process ◽  
Vitro Fertilization ◽  
Cultural Traditions ◽  
Cultural Aspects ◽  
The One ◽  
The Impact

The paper provides a definition of sexual and reproductive health and infertility and also reflects modern ideas about ways to overcome infertility using assisted reproductive technologies, such as in vitro fertilization (IVF) and surrogacy. It shows the specificity of the impact of an IVF procedure on the mental health of a potential mother. The features of the neonatal health status, as well as neuropsychiatric disorders in babies born using the IVF procedure are described. The authors present two types of surrogacy (traditional and gestational ones) and the features of their use in different countries according to governmental legislative regulation, socioeconomic and religious factors, and cultural traditions in society. They unveil the features of a psychological relationship between the mother (surrogate and presumed one) and the fetus. The consequences of surrogacy for a surrogate mother, genetic parents, and a child himself/herself are noted to be little studied. It is shown that the development of assisted reproductive technologies (IVF and surrogacy), on the one hand, helps fight infertility and, on the other hand, entails a number of problems (moral and ethical, legal, cultural and religious, socioeconomic, and neuropsychiatric ones) that need to be solved in order to prevent psychological, neurological, and mental abnormalities in all the participants (a surrogate mother, an unborn child, and potential parents) in the assisted reproductive process:

scholarly journals Legal Responsibility for Abuses and Crimes in the Field of Artificial Human Reproduction

Lex Russica ◽  
2019 ◽  
pp. 48-52
Author(s):  
N. V. Kruchinina
Keyword(s):  
Human Rights ◽  
Assisted Reproductive Technologies ◽  
Reproductive Technologies ◽  
Human Reproduction ◽  
Legal Responsibility ◽  
Human Beings ◽  
Artificial Reproduction ◽  
Forensic Research ◽  
Human Reproductive ◽  
Common Understanding

The article analyzes different points of view concerning reproductive human rights. Every year the number of cases when assisted reproductive technologies are used is increasing in Russia. The author draws attention to the lack of a common understanding of reproductive human rights, their protection and regulation in different countries of the world, to different perceptions of legal responsibility for abuses in the field of artificial reproduction of human beings, and to the existence of different definitions of crime in the field of human reproduction.The article presents an overview of foreign legislation on criminal law protection of human reproductive functions. The study of criminal and civil cases and examination of scientific developments in this area compels the author to admit the existence of abuses and crimes in the field of artificial reproduction of human beings. The article attempts to determine the list of crimes against reproductive human rights and considers them as an object of forensic research.

scholarly journals New normativity and reproductive choice: an attempt at comprehension

2020 ◽  
Vol 4 (4) ◽  
pp. 74-83
Author(s):  
Svetlana A. Bronfman
Keyword(s):  
Assisted Reproductive Technologies ◽  
Reproductive Technologies ◽  
Traumatic Experience ◽  
Reproductive Choice ◽  
Transgenerational Transmission ◽  
Voluntary Childlessness ◽  
Moral Content ◽  
Culture Of Violence ◽  
Public Opinion Polls ◽  
Opinion Polls

The article discusses two “special types” of reproductive choices – combating infertility through assisted reproductive technologies and voluntary childlessness. Particular attention is paid to the phenomenon of voluntary childlessness. Basing on the analysis of public opinion polls, reconstruction of historical realities of the second half of XX century, normogenesis studies, new psychodynamic theories of transgenerational transmission of traumatic experience, and philosophical ideas of intentionality of acceptance and hospitality, the author analyzes the existing reproductive practices in their connection with procreative norms. The reasons for the increasing spread of voluntary childlessness, according to the author of the article, are largely connected to the transgenerational transmission of experience of violence. The author’s hypothesis is based on psychodynamic ideas about transgenerational trauma and perverse maternal attitude and is that the spread of the voluntary childlessness in the generation of the 1990s may be caused by the impossibility of hospitality, acceptance, and vulnerability due to the lack of failure of the maternal functionary as a container and the lack of introjects of loving and guiding parent figures (“empty superego”). Thus, the new “shapeless” normativity, creating the illusion of “freedom to be oneself”, may prove to be a projection of a split, lifeless and empty collective unconscious superego, generated by a culture of violence that requires moral content, which has been abolished.

scholarly journals A clinical example of the management of a premature baby born after IFV

2019 ◽  
pp. 141-145
Author(s):  
N. A. Druzhinina ◽  
D. R. Merzlyakova ◽  
G. P. Shiryaeva
Keyword(s):  
Nervous System ◽  
Assisted Reproductive Technologies ◽  
Subsequent Development ◽  
Reproductive Technologies ◽  
Premature Baby ◽  
Extremely Low Birth Weight ◽  
Medical Documentation ◽  
Central Nervous System Damage ◽  
Premature Babies

Babies born through in vitro fertilization (IVF) treatment are most often born preterm [1]. Most authors state that these children are more likely to have congenital malformations, bronchopulmonary dysplasia (BPD), hypoxic central nervous system damage, hyperbilirubinemia. It is known that these children are 6 times more likely to have an extremely low birth weight and intrauterine growth retardation [2]. More than 35 years have passed since the birth of the first child through the IVF treatment. During this time, the assisted reproductive technologies have improved and therewith the number of children conceived in vitro has also increased. In this regard, the issues relating to the study of the health of children conceived through IVF treatment are growing more urgent. In the Russian Federation, the share of premature babies averages 6–8% among all newborns. Children born prematurely should always be in the center of attention of pediatricians, since it is among them that the highest percentage of perinatal pathology is observed and deviations in subsequent development are detected much more often [3].Objective of the study: to study the state of health of a premature baby in the first year of life born through IVF. Material and methods: the researchers performed a continuous, documentary, retrospective analysis of the medical history of a child treated in the Special Care Nursery of the City Children’s Clinical Hospital in Ufa, and afterwards monitored the child in the Catamnesis Unit. The child underwent clinical examination, assessment of physical development using the centile method, laboratory tests, analysis of primary medical documentation (hospital neonatal record f. 097/u, outpatient medical record f. 112/u). The premature baby was examined taking into account the adjusted age (from the calendar age to 40 weeks of gestation).Results: the health and age of the mother are crucial in forming the health of the child. The mother had a combined pathology. The 3rd pregnancy (the 1st pregnancy ended in childbirth at 35 weeks, the child grows in a family, the 2nd pregnancy ended in spontaneous abortion) through IVF treatment developed against the threat of interruption starting from 8 weeks, combined gestosis, grade 1B placental violation, low placentation, isthmic-cervical insufficiency (ICI), antiphospholipid syndrome, which resulted in early, premature birth at 29 weeks’ gestational age. The child was born prematurely with perinatal nervous system damage, the development of acute pneumonia, respiratory distress syndrome of the newborn.Findings: A clinical case determines the need for targeted observation of a premature child from a risk group, timely advanced training of a pediatrician regarding the features of management of premature babies born through the IVF treatment, taking into account the adjusted age.

scholarly journals To understand the reproductive tract microbiome associated with infertility through metagenomics analysis

2021 ◽  
Vol 26 (1) ◽  
Author(s):  
Manisha Vajpeyee ◽  
Lokendra Bahadur Yadav ◽  
Shivam Tiwari ◽  
Parikshit Tank
Keyword(s):  
Reproductive Tract ◽  
Assisted Reproductive Technologies ◽  
Live Birth Rate ◽  
Reproductive Technologies ◽  
Female Reproductive Tract ◽  
Human Reproduction ◽  
Main Body ◽  
Fertility Treatments ◽  
Vaginal Tract ◽  
Human Illness

Abstract Background Knowledge of the microbiome is in its infancy in health and human illness, especially concerning human reproduction. We will be better able to treat dysbiosis of the reproductive tract clinically if it is better explained and understood. It has been shown that altered vaginal microbiota affects parturition, and its function is uncertain in assisted reproductive technologies. However, the effects of recognized microbes such as Mycoplasma tuberculosis, Chlamydia trachomatis, and Neisseria gonorrhoeae are well established, resulting in subclinical changes which are considered to be risk factors for infertility and poor reproductive outcomes. Main body Recent studies indicate that the vaginal tract comprises several different organisms of the microbiome. Some microbiota can play an important role not only in the reproductive tract but also in overall health. The microbiome of the female reproductive tract has been identified mainly based on studies that examine vaginal samples across many reproductive technologies, using a metagenomics approach. Conclusion Alteration of reproductive tract microbiota or presence of certain microbiota irrespective of the level of pathogenicity may interfere with fertilization, implantation, and subsequent embryo development. This may lead to failed fertility treatments and reduced live birth rate (LBR).

Acentriolar spindle assembly in mammalian female meiosis and the consequences of its perturbations on human reproduction

2021 ◽  
Author(s):  
Cecilia S Blengini ◽  
Karen Schindler
Keyword(s):  
Assisted Reproductive Technologies ◽  
Reproductive Technologies ◽  
Human Reproduction ◽  
Meiotic Spindle ◽  
Female Meiosis ◽  
Spindle Formation ◽  
Cellular Machinery ◽  
Meiotic Spindles ◽  
Mammalian Female ◽  
Oocyte Meiotic Maturation

Abstract The purpose of meiosis is to generate developmentally competent, haploid gametes with the correct number of chromosomes. For reasons not completely understood, female meiosis is more prone to chromosome segregation errors than meiosis in males, leading to an abnormal number of chromosomes, or aneuploidy, in gametes. Meiotic spindles are the cellular machinery essential for the proper segregation of chromosomes. One unique feature of spindle structures in female meiosis is spindles poles that lack centrioles. The process of building a meiotic spindle without centrioles is complex and requires precise coordination of different structural components, assembly factors, motor proteins, and signaling molecules at specific times and locations to regulate each step. In this review, we discuss the basics of spindle formation during oocyte meiotic maturation focusing on mouse and human studies. Finally, we review different factors that could alter the process of spindle formation and its stability. We conclude with a discussion of how different assisted reproductive technologies (ART) could affect spindles and the consequences these perturbations may have for subsequent embryo development.

Law in Ensuring the Safety of Genetic Technologies Against their Use for Criminal Purposes

Lex Russica ◽  
2020 ◽  
pp. 47-53
Author(s):  
N. V. Kruchinina
Keyword(s):  
Legal Status ◽  
Assisted Reproductive Technologies ◽  
Reproductive Technologies ◽  
Legal Framework ◽  
Legal Regulation ◽  
Human Reproduction ◽  
Economic Progress ◽  
Genetic Technologies ◽  
Criminal Groups ◽  
Definition Of

Genetic technologies offer wide prospects for socio-economic progress. At the same time, their application in practice could put at stake the interests of society, human rights and freedoms. Therefore, the development of genetic technologies requires its analysis from the standpoint of jurisprudence, thoughtful legislative regulation and protection from uncontrolled spread and criminal use. The paper analyzes different points of view on the use of genetic technologies. The author substantiates the necessity of proper legal regulation and security of the process of development of genetic technologies. The paper contains the results of the scientific research. The paper elucidates the problems related to the use of genetic technologies in the process of artificial human reproduction: imperfection of the legal framework (In particular, lack of the definition of the legal status of human embryo, lack of justification for the legality of its use for research and therapeutic purposes), the threat of the use of genetic technologies for criminal purposes. The author concludes that the use of genetic technologies for criminal purposes is especially dangerous because organized criminal groups focus their attention on genetic technologies. This gives rise to a special criminal situation that requires new approaches for effective counteraction. To this end, the priority is given to identification of crimes committed with the use of genetic technologies and analysis of the emerging practice of investigating this category of crimes. Failure to comply with standards, deviation from regulations and procedures imposed on medical care may result in harm to health or death also when the assisted reproductive technologies are used. The author has made some proposals to solve these problems with due regard to domestic and foreign experience in the use of genetic technologies in the field of human artificial reproduction (in particular, it is proposed to establish effective international cooperation in this area).

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