scholarly journals Resistance to doxorubicin correlated with dysregulation of microRNA-451 and P-glyoprotein, caspase 3, estrogen Receptor on Breast Cancer cell line

2019 ◽  
Vol 51 (04) ◽  
Author(s):  
Indwiani Astuti ◽  
Torizal GF ◽  
Sa’adah N ◽  
Oktriani R ◽  
Wardana T ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Estrogen Receptor ◽  
Cell Line ◽  
Cancer Cell ◽  
Breast Cancer Cell ◽  
Breast Cancer Cell Line ◽  
Caspase 3 ◽  
Cancer Cell Line ◽  
Resistance To Doxorubicin

scholarly journals Estrogen receptor (ER) β1 and ERβcx/β2 inhibit ERα function differently in breast cancer cell line MCF7

Oncogene ◽  
2003 ◽  
Vol 22 (32) ◽  
pp. 5011-5020 ◽  
Author(s):  
Yoko Omoto ◽  
Hidetaka Eguchi ◽  
Yuri Yamamoto-Yamaguchi ◽  
Shin-ichi Hayashi
Keyword(s):  
Breast Cancer ◽  
Estrogen Receptor ◽  
Cell Line ◽  
Cancer Cell ◽  
Breast Cancer Cell ◽  
Breast Cancer Cell Line ◽  
Cancer Cell Line

ChIP-seq predicted estrogen receptor biding sites in human breast cancer cell line MCF7

Tumor Biology ◽  
2014 ◽  
Vol 35 (5) ◽  
pp. 4779-4784 ◽  
Author(s):  
Qi Li ◽  
Huichun Wang ◽  
Leyang Yu ◽  
Jun Zhou ◽  
Jingde Chen ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Estrogen Receptor ◽  
Cell Line ◽  
Cancer Cell ◽  
Breast Cancer Cell ◽  
Breast Cancer Cell Line ◽  
Human Breast Cancer ◽  
Cancer Cell Line ◽  
Human Breast Cancer Cell ◽  
Human Breast

scholarly journals Paclitaxel liposomes exert radio-sensitization effect on breast cancer cell line SK-BR-3 by regulating expressions of apoptotic proteins

2020 ◽  
Vol 19 (5) ◽  
pp. 1009-1013
Author(s):  
Guoling Yin ◽  
Xiaoping Li ◽  
Xiaofei Chang
Keyword(s):  
Breast Cancer ◽  
Cell Line ◽  
Cancer Cell ◽  
Breast Cancer Cell ◽  
Breast Cancer Cell Line ◽  
Caspase 3 ◽  
Cancer Cell Line ◽  
Combination Group ◽  
Apoptotic Proteins ◽  
Sensitization Effect

Purpose: To study the radio-sanitization effect of paclitaxel liposomes on breast cancer cells, SK-BR-3.Methods: Breast cancer cell line SK-BR-3 was cultured and made into a cell suspension. Four groups of cells were used: control and radiotherapy groups, paclitaxel group, and paclitaxel liposome + radiotherapy group (combination group). The growth inhibitory effects of the different treatments on SKBR-3 cells were determined with CCK-8 method. Apoptosis in each group was evaluated with flow cytometry, while Western blotting was employed to assay Bcl-2, Caspase-3 and Bax protein levels.Results: There were marked inhibitory effect on growth of SK-BR-3 cells in drug, radiotherapy and combination groups, relative to control, while apoptosis was greater in combination group than in drug and radiotherapy groups (p < 0.05). The Bcl-2 protein level was higher in radiotherapy, drug and combination groups than in control group, while Caspase-3 and Bax proteins were markedly higher thancontrol values (p < 0.05).Conclusion: Paclitaxel liposomes exert radio-sensitization effect on SK-BR-3 by regulating the levels of apoptotic proteins. This provides a basis for research and development of new drugs. Keywords: Paclitaxel liposomes, Apoptotic proteins, Breast cancer, SK-BR-3, Radiotherapy, Sensitization, Bcl-2, Caspase-3, Bax

Sign in / Sign up

Export Citation Format

Share Document