scholarly journals Changes in corneal thickness and corneal endothelial cell density after phacoemulsification cataract surgery: a double-blind randomized trial

10.19082/6616 ◽  
2018 ◽  
Vol 10 (4) ◽  
pp. 6616-6623 ◽  
Author(s):  
Shahram Bamdad ◽  
Alireza Bolkheir ◽  
Mohammad Reza Sedaghat ◽  
Mahsa Motamed
Keyword(s):  
Endothelial Cell ◽  
Cataract Surgery ◽  
Randomized Trial ◽  
Cell Density ◽  
Corneal Thickness ◽  
Corneal Endothelial Cell ◽  
Endothelial Cell Density ◽  
Double Blind ◽  
Corneal Endothelial Cell Density ◽  
Phacoemulsification Cataract Surgery

scholarly journals Corneal endothelial cell density loss following glaucoma surgery alone or in combination with cataract surgery: a systematic review protocol

BMJ Open ◽  
2021 ◽  
Vol 11 (9) ◽  
pp. e050992
Author(s):  
Clarissa E H Fang ◽  
Peng Tee Khaw ◽  
Rashmi G Mathew ◽  
Christin Henein
Keyword(s):  
Endothelial Cell ◽  
Cataract Surgery ◽  
Cell Density ◽  
Systematic Reviews ◽  
Glaucoma Surgery ◽  
Corneal Endothelial Cell ◽  
Endothelial Cell Density ◽  
Controlled Trials ◽  
Surgical Trauma ◽  
Corneal Endothelial Cell Density

ObjectiveWe aim to systematically assess and compare corneal endothelial cell density (ECD) loss in patients with glaucoma following glaucoma surgery and cataract surgery.IntroductionCorneal ECD loss may occur due to intraoperative surgical trauma in glaucoma surgery or postoperatively with chronic endothelial cell trauma or irritation. Corneal oedema and decompensation after aqueous shunt glaucoma surgery has been reported but the long-term ECD loss is still unknown.Inclusion criteriaTrabeculectomy, glaucoma filtration surgery or microinvasive glaucoma surgery in adults with ocular hypertension, primary and secondary open angle glaucoma, normal tension glaucoma and angle-closure glaucoma. Participants with pre-existing corneal disease will be excluded. Glaucoma laser treatments and peripheral iridotomy will be excluded. The outcomes include preoperative and postoperative corneal ECD, percentage change of corneal ECD and adverse events.MethodsWe will conduct an electronic database search for randomised controlled trials, prospective non-randomised studies, observational studies in MEDLINE, EMBASE, Cochrane Central Register of Controlled Trials (CENTRAL), ClinicalTrials.gov and The International Prospective Register of Systematic Reviews (PROSPERO). Eligibility criteria will include quantitative articles published after and including the year 2000, written in English and containing data on ECD loss. Two independent reviewers will screen titles and abstracts and extract data from full texts, reporting outcomes according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Data extraction of key characteristics will be completed using customised forms. Methodological quality will be assessed using the Joanna Briggs Institute critical appraisal forms.Ethics and disseminationEthics approval is not required for this review, as it will only include published data. Findings will be published in a peer-reviewed journal and disseminated across ophthalmic networks.PROSPERO registration numberPROSPERO CRD42020192303.

Corneal Endothelial Cell Density After Trypan Blue Capsule Staining in Cataract Surgery

2002 ◽  
Vol 28 (4) ◽  
pp. 574-575 ◽  
Author(s):  
Bart T.H. van Dooren ◽  
Peter W.T. de Waard ◽  
Hester Poort-van Nouhuys ◽  
Houdijn W. Beekhuis ◽  
Gerrit R.J. Melles
Keyword(s):  
Endothelial Cell ◽  
Cataract Surgery ◽  
Cell Density ◽  
Trypan Blue ◽  
Corneal Endothelial Cell ◽  
Endothelial Cell Density ◽  
Corneal Endothelial Cell Density

Outcomes of cataract surgery in eyes with a low corneal endothelial cell density

2011 ◽  
Vol 37 (12) ◽  
pp. 2130-2136 ◽  
Author(s):  
Katsuya Yamazoe ◽  
Takefumi Yamaguchi ◽  
Kazuki Hotta ◽  
Yoshiyuki Satake ◽  
Kenji Konomi ◽  
...  
Keyword(s):  
Endothelial Cell ◽  
Cataract Surgery ◽  
Cell Density ◽  
Corneal Endothelial Cell ◽  
Endothelial Cell Density ◽  
Corneal Endothelial Cell Density

scholarly journals Study of Changes in Corneal Thickness and Corneal Endothelial Cell Density after Phacoemulsification Cataract Surgery

2021 ◽  
Vol 10 (12) ◽  
pp. 866-872
Author(s):  
Rajiv Pardasani ◽  
Sohan Lohiya
Keyword(s):  
Endothelial Cell ◽  
Cell Density ◽  
Coefficient Of Variation ◽  
Central Corneal Thickness ◽  
Corneal Thickness ◽  
Cell Loss ◽  
Corneal Endothelial Cell ◽  
Endothelial Cell Density ◽  
P Value ◽  
Corneal Endothelial Cell Density

BACKGROUND Phacoemulsification is a common surgery for cataract. The endothelium comprises of hexagonal cells which in single layer is essential for maintaining the transparency of the cornea. We wanted to compare endothelial cell density (ECD), central corneal thickness (CCT), coefficient of variability, and hexagonality of endothelial cells before and after phacoemulsification surgery. we also wanted to evaluate the endothelial cell loss after phacoemulsification surgery. METHODS A rural hospital-based prospective observational study with 120 patients was conducted in a hospital based setting utilising the data of patient’s eye by considering inclusion and exclusion criteria, before and after phacoemulsification surgery by using noncontact specular microscope. RESULTS The mean endothelial cell density significantly decreased postoperatively at day one, 4th week, 12th week. The mean central corneal thickness increased significantly at postoperative day one, then subsequently decreased at postoperative 4th week and 12th week (P value = 0.0001), but never reached the preoperative value. There was a significant change in coefficient of variation and hexagonality postoperatively (P value = 0.0001). CONCLUSIONS The primary result is the change in corneal endothelial cell density (cells per square millimetre of the corneal surface) which is decreased, and the central corneal thickness calculated in micro meter is increased. As endothelial cells do not replicate, to reimburse cell loss there are changes in coefficient of variation and hexagonality after phacoemulsification surgery. KEY WORDS Corneal Endothelial Cell Density, Central Corneal Thickness, Coefficient of Variation, Hexagonality, Phacoemulsification, Specular Microscope

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