scholarly journals Study of central corneal thickness using non-contact techniques: Specular microscopy (Nidek CEM-530), corneal tomography (Pentacam HR), and optical coherence tomography (Cirrus HD-OCT 5000) in healthy adult patients

2018 ◽  
Vol 16 (1) ◽  
pp. 25-31
Author(s):  
Patricia González-Rodríguez ◽  
Vanesa Blázquez-Sánchez ◽  
Sara Fernández-Cuenca
Keyword(s):  
Optical Coherence Tomography ◽  
Central Corneal Thickness ◽  
Healthy Adult ◽  
Adult Population ◽  
Corneal Thickness ◽  
Adult Patients ◽  
Specular Microscopy ◽  
Optical Coherence ◽  
Significant Difference ◽  
Corneal Tomography

Objective: To study and compare the value of central corneal thickness in a healthy adult population, using different non-contact techniques from daily clinical practice. Method: This work examines and compares the pachymetric measurements of 71 eyes of 36 healthy adult patients. Corneal thickness was evaluated using three non-contact instruments: a CEM-530 specular microscope (Nidek), Pentacam HR corneal tomography (Oculus), and Cirrus HD-OCT 5000 optical coherence tomography (Carl Zeiss Meditec). Tests were performed consecutively by a single observer in the same session and under the same environmental conditions. Results: The results obtained using the three devices are interchangeable, given that no statistically significant difference was observed among them. The study did not find statistically significant difference with respect to gender either. Conclusion: These three non-contact methods for the measurement of corneal central pachymetry are a reliable alternative to ultrasonic contact pachymetry.

scholarly journals Comparison of Four Methods for Corneal Thickness Measurement

2013 ◽  
Vol 6 (1) ◽  
pp. 37-42
Author(s):  
Teodora L. Marinova ◽  
Vesela Ivancheva ◽  
Svilena S. Peeva ◽  
Christina N. Grupcheva
Keyword(s):  
Optical Coherence Tomography ◽  
Laser Scanning ◽  
Central Corneal Thickness ◽  
Corneal Thickness ◽  
Anterior Segment ◽  
Laser Scanning Confocal Microscopy ◽  
Thickness Measurement ◽  
Specular Microscopy ◽  
Optical Coherence ◽  
Cornea Thickness

Summary The aim of the study was to evaluate the thickness of the normal cornea in order to establish correlation between four methods of measuring including: ultrasound pachymetry (USP), anterior segment optical coherence tomography (ASOCT), non-contact tono/pachymetry (TONOPACHY) and laser-scanning confocal microscopy (LSCM). The study was based on evaluating repeatability and comparability of four different methods formeasuring the corneal thickness. Non contact specular microscopy was first performed on all 27 patients (aged between 20 and 24 years) to evaluate corneal characteristics and confirm the absence of pathological changes. Each participant was examined by USP, ASOCT and TONOPACHY, and 13 eyes of 10 persons were also examined by LSCM. The values of average central corneal thickness measured by USP, ASOCT, TONOPACHY and LSCM were 532.20±4.5 pm, 553.33±12.1 pm, were 548.20±5.62 pm and 573.33±7.22 pm, respectively. There was a high correlation between the instruments. The mean differences for central corneal thickness measurements were 41.43±1.67 pm between USP and LSCM, 20.43±2.4 pm between USP and ASOCT, and 22.1 ±3.88 pm between USB and TONOPACHY. Anterior segment optical coherence tomography overestimated corneal thickness as compared with that measured by USP, which is believed to be a gold standard. Anterior segment optical coherence tomography had better agreement with USP, as compared with LSCM. However, the results of measured cornea thickness by TONOPACHY were very close to cornea thickness measured by ASOCT.

scholarly journals Agreement between anterior segment Optical Coherence Tomography, Lenstar and Ultrasound Biomicroscopy measurements of anterior segment parameters

2019 ◽  
Author(s):  
Ziyan Yu ◽  
Ting Huang ◽  
Qiao Yu ◽  
Jun Kong ◽  
Bo Qu
Keyword(s):  
Optical Coherence Tomography ◽  
Anterior Chamber ◽  
Central Corneal Thickness ◽  
Corneal Thickness ◽  
Anterior Segment ◽  
Anterior Chamber Depth ◽  
Ultrasound Biomicroscopy ◽  
Optical Coherence ◽  
Significant Difference ◽  
Medical University

Abstract Purpose To compare anterior chamber depth (ACD) and central corneal thickness (CCT) measurements by anterior segment optical coherence tomography (AS-OCT), Lenstar and ultrasound biomicroscopy (UBM). Methods A retrospective cross section study. A total of 83 eyes from 54 patients were included. Central corneal thickness (CCT) and anterior chamber depth (ACD) values obtained from three devices (AS-OCT, Lenstar and UBM) were recorded. All patients were collected from Oct. 2015 to Aug. 2016 in the Fourth Affiliated Hospital of China Medical University. Differences of these three devices (ACD and CCT) were statistically analyzed by randomized blocks analysis. Pearson correlative analysis and Bland-Altman analysis were used to compare the correlation and agreement. Results There’s no significant difference in measuring ACD by Lenstar and UBM (P>0.05), but there were significant differences in other two groups (AS-OCT and UBM, AS-OCT and Lenstar) (P<0.05). There were significant differences in the mean CCT measured by the three devices (P<0.05). There were high correlation in measuring ACD (all P<0.001, r1=0.928,r2=0.982,r3=0.932, respectively), and CCT(all P<0.001,r1=0.957,r2=0.949,r3=0.928, respectively). Conclusion AS-OCT, Lenstar and UBM yielded comparable results and are all can be used interchangeably for anterior segment measurements.

Comparative study of the central corneal thickness in healthy individuals and diabetic patients with and without retinopathy using anterior segment optical coherence tomography

QJM ◽  
2021 ◽  
Vol 114 (Supplement_1) ◽  
Author(s):  
Tamer F El-Mekkawi ◽  
Hazem O Rashed ◽  
Hisham S. Saad Eldin ◽  
Hagar M Faisal
Keyword(s):  
Optical Coherence Tomography ◽  
Diabetic Retinopathy ◽  
Comparative Study ◽  
Central Corneal Thickness ◽  
Corneal Thickness ◽  
Anterior Segment ◽  
Diabetic Patients ◽  
Optical Coherence ◽  
Chronic Hyperglycemia ◽  
Significant Difference

Abstract Background Chronic hyperglycemia in diabetes mellitus causes different morphologic and functional corneal changes. Aim of the Work to assess the central corneal thickness in diabetic patients with and without diabetic retinopathy using anterior segment optical coherence tomography. Patients and Methods This comparative study was conducted at Ain Shams University hospitals . It included 45 eyes divided into three groups: Group A: 15 eyes of diabetic patients without diabetic retinopathy , Group B: 15 eyes of diabetic patients with diabetic retinopathy and Group C: 15 eyes of non-diabetic individuals. Results : The mean CCT in diabetic patients without diabetic retinopathy was 551.13µ ± 37.93 with range 475-622. Diabetics with retinopathy was 558.93µ ± 39.32 with range 508-618 and non diabetics 534.73µ ± 33.67 with range 475-588. There was no significant difference in corneal thickness between the three groups (p = 0.201) Conclusion : Diabetic corneas tended to be thicker though this was not statistically significant in our work.

scholarly journals Correlation between Central Corneal Thickness and Degree of Myopia among Malaysian Patients Undergoing Laser Keratorefractive Surgery

2020 ◽  
pp. 52-58
Author(s):  
Sagili Chandrasekhara Reddy ◽  
Mohd Mansor Shariff ◽  
Aina Malindri Dasrilsyah
Keyword(s):  
Optical Coherence Tomography ◽  
Refractive Surgery ◽  
Central Corneal Thickness ◽  
Corneal Thickness ◽  
Anterior Segment ◽  
Military Hospital ◽  
Moderate Degree ◽  
Optical Coherence ◽  
Corneal Refractive Surgery ◽  
The Mean

Purpose: To determine the central corneal thickness in myopic adult patients scheduled for laser corneal refractive surgery and to explore its correlation with degree of refractive error. Materials and Methods: The case records of 130 myopic patients who underwent laser corneal refractive surgery in a military hospital over a period of two years were reviewed to determine the central corneal thickness. All patients had 6/6 vision with best correction, and did not have any other anterior segment or fundus diseases in both eyes. The central corneal thickness was measured with Visante Carl Zeiss anterior segment optical coherence tomography instrument.                                                                                                                        Results: Out of 130 patients, males were more (73, 56.2%); mean age of patients was 33.8 years (range 18-60 years) and majority were Malays (110, 84.6%).  The spherical power of myopia ranged from – 0.5 to – 10.00 D, and the cylindrical power ranged from – 0.25 to – 3.25 D. The mean central corneal thickness of both eyes was 528.2 µm (range 331- 615 µm); in the mild degree of myopia (- 0.50 to - 2.00 D) 527.9 µm, moderate degree (- 2.25 to -5.00 D) 529.4 µm, and high degree (-5.25 to -11.00 D) 523.9 µm. Conclusion: The anterior segment optical coherence tomography provides noncontact, rapid, pachymetry mapping of the corneal thickness. In Malaysian patients, the mean central corneal thickness of both eyes in myopia was 528.1 µm (range 331- 615 µm). There was no correlation between the mean central corneal thickness and degree of myopia, different genders, age groups, ethnic groups and two eyes.

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