scholarly journals PATTERNS OF CHANGES IN FLUORESCENCE OF NADH AND FAD COENZYMES AND THEIR RELATIONSHIP IN SKELETAL MUSCLE IN EARLY POST-MORTEM PERIOD (EXPERIMENTAL STUDY)

2020 ◽  
Author(s):  
Anastasia S. Babkina
Keyword(s):  
Skeletal Muscle ◽  
Mathematical Models ◽  
Fluorescence Intensity ◽  
Statistical Significance ◽  
Linear Regression Analysis ◽  
Post Mortem ◽  
Redox Ratio ◽  
Measuring Device ◽  
Nadh Fluorescence ◽  
The Relationship

Abstract. The paper presents changes and mathematical models of autofluorescence of reduced nicotinamide adenine dinucleotide (NADH) and flavin adenine dinucleotide (FAD) and their redox ratio (RR) in the rat skeletal muscle during the first 24 hours after death. Aim. To establish a pattern of change in the fluorescence intensity of NADH and FAD coenzymes, as well as their relationship in the skeletal muscle during the first 24 hours after death using mathematical modeling. Material and methods. The experiment was performed on Sprague Dawley rats. The fluorescence intensity of FAD and NADH coenzymes in skeletal muscle was measured in situ in living rats under general anesthesia, 5 minutes after euthanasia, and at intervals of 1.5-3 h during the 24-hour postmortem period. To estimate the fluorescence intensity of NADH and FAD coenzymes and to calculate the RR, the Lasma MC-3 fluorescence measuring device with special software was used. The obtained data were analyzed by non-linear regression analysis. The summary, accuracy estimation and significance of the regression equation coefficients were assessed using SigmaPlot 10.0 software. The significance of the regression model was tested using the Fisher F-criterion. Results. During the first 3 hours of the postmortem period, an increase in the mean values of RR and NADH fluorescence was detected, starting from 4.5 and till 24 hours post-mortem their gradual decrease was observed. The relationship between NADH, RR and time after death is characterized by the Weibull equation. The statistical significance of NADH and RR models, based on the obtained equations was considered high. Conclusion. The analysis of the obtained data allowed to create mathematical models describing the relationship between RR and NADH fluorescence intensity and time after death, which confirms non-randomness and regularity of the discovered patterns.time of death; NADH; FAD; auto-fluorescence; redox ratio; early post-mortem changes

The Relationship between Blood and Urine Alcohol Concentrations at Autopsy

1989 ◽  
Vol 29 (3) ◽  
pp. 209-217 ◽  
Author(s):  
M. K. Heatley ◽  
J. Crane
Keyword(s):  
Regression Analysis ◽  
Linear Regression Analysis ◽  
Blood Alcohol Concentration ◽  
Alcohol Concentration ◽  
Blood Alcohol ◽  
Post Mortem ◽  
Post Mortem Interval ◽  
Average Ratio ◽  
Simple Ratio ◽  
The Relationship

The relationship between the blood alcohol concentration and the urine alcohol concentration was studied in 109 routine coroner's autopsies. Although the average ratio for urine alcohol concentration to blood alcohol concentration lay close to the ratio of 4:3 quoted in the literature, the actual ratios determined were widely scattered around this value. Thus the use of this simple ratio to estimate the blood alcohol concentration from the urine alcohol concentration at post-mortem was unreliable. An equation determined by employing linear regression analysis was similarly unhelpful in enabling one to derive a precise value for the blood alcohol concentration from a given urine alcohol concentration. It was concluded that the main value in determining the urine alcohol concentration at autopsy was to exclude the possibility of the alcohol present in the blood sample having been generated during the post-mortem interval.

Determination of the fluorescence intensity of coenzymes NADH and FAD in the skeletal muscle of the rat depending on the post-mortem interval

2020 ◽  
Vol 63 (1) ◽  
pp. 31
Author(s):  
A. S. Babkina ◽  
D. V. Sundukov ◽  
A. M. Golubev ◽  
I. A. Ryzhkov ◽  
Z. I. Tsokolaeva ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Fluorescence Intensity ◽  
Post Mortem ◽  
Post Mortem Interval

scholarly journals The Relationship Between Self-Efficacy and Fluid and Dietary Compliance in Hemodialysis Patients

2013 ◽  
Vol 6 (2) ◽  
pp. 98-104 ◽  
Author(s):  
Ansy John ◽  
Patricia T. Alpert ◽  
Jennifer Kawi ◽  
Richard Tandy
Keyword(s):  
Self Efficacy ◽  
Statistical Significance ◽  
Linear Regression Analysis ◽  
Fluid Restriction ◽  
Dietary Compliance ◽  
Strict Adherence ◽  
Dietary Restrictions ◽  
Stage Renal Disease ◽  
End Stage ◽  
The Relationship

Patients with end-stage renal disease (ESRD) require complex medical management that necessitates strict adherence to their treatment program. But why individuals are noncompliant with their prescribed therapeutic regimen is not well understood. The purpose of this study was to determine the relationship between self-efficacy and self-reported fluid and dietary compliance as well as identify the possible barriers that prevented patient compliance. One hundred ESRD patients who received hemodialysis three times a week participated. Bivariate correlational analysis showed there were strong positive correlations between self-efficacy and daily fluid (r = .56; p < .001) and dietary (r = .53; p < .001) restrictions. Linear regression analysis was used to analyze the potential barriers predicted for fluid and dietary compliance, which also showed statistical significance. The results showed those who reported being in social gatherings were less compliant with fluid and dietary restrictions (F[1, 90] = 14.62, p < .001). Similarly, those who reported greater frustration with kidney disease reported less compliance with fluid and dietary restrictions (F[1, 90] = 4.65, p < .01). By using the results of this study, clinicians and nurses can adopt multiple strategies to improve patient self-efficacy levels and self-management capacities. This study also provides a better understanding of barriers that prevents dietary and fluid restriction compliance.

Study of the infl uence of information and communication tools on the psychophysiological state of schoolchildren on the basis of subjective evaluation

2020 ◽  
pp. 47-55
Author(s):  
Aleksandra Rakhmanova ◽  
Georgiy Loginov ◽  
Vladimir Dolich ◽  
Nataliya Komleva ◽  
Galina Rakhmanova
Keyword(s):  
High School ◽  
Emotional State ◽  
Statistical Significance ◽  
Subjective Evaluation ◽  
Educational Process ◽  
The Body ◽  
Leningrad Region ◽  
Communication Tools ◽  
Information And Communication ◽  
The Relationship

The relevance of the article is determined by the existence of contradictions between the need to introduce innovative technologies into the educational process at school, as an integral attribute of modern education, and the negative influence of factors on the physical and psycho-emotional state of health of students related to the use of information and communication tools (computers, phones, headphones). The goal of the study was to assess the relationship between the timing of the use of information and communication tools and the frequency of functional and psycho-emotional complaints in groups of middle and high school schoolchildren. 400 schoolchildren of the Saratov Region, the Moscow Region, Leningrad Region and the Republic of Dagestan were surveyed, who made up two groups of research: middle-school schoolchildren (grades 5–6) and high-school schoolchildren (grades 10–11 The survey was carried out by means of the standardized formalized cards which included the questions considering usage time of computers and mobile phones, complaints to a headache, hands pain, other pain and/or feeling of discomfort from visual organ and the organs of hearing, as well as a psycho-emotional state. Statistical analysis of the data was performed using the STATISTICA application software program by StatSoft Inc (USA). To compare the frequencies of a binary feature, a fourfold table of absolute frequencies was constructed and the level of statistical significance for the exact Fisher’s two-tailed test criterion was determined. The study was conducted according to the requirements of bioethics, after signing informed consent statement by teenagers and their parents. The study examined the relationship between the timing of the use of information and communication tools and the frequency of complaints in groups of schoolchildren. The results of the study should be taken into account when developing and implementing preventive measures to prevent negative effects of computers and mobile devices on the body of students.

The Influences of Palindromes in mRNA on Protein Folding Rates

2020 ◽  
Vol 27 (4) ◽  
pp. 303-312 ◽  
Author(s):  
Ruifang Li ◽  
Hong Li ◽  
Sarula Yang ◽  
Xue Feng
Keyword(s):  
Protein Folding ◽  
Regression Analysis ◽  
Linear Regression ◽  
Linear Regression Analysis ◽  
Folding Rate ◽  
Folding Rates ◽  
Negative Linear Correlation ◽  
Protein Folding Rate ◽  
The Relationship ◽  
Structure Environment

Background: It is currently believed that protein folding rates are influenced by protein structure, environment and temperature, amino acid sequence and so on. We have been working for long to determine whether and in what ways mRNA affects the protein folding rate. A large number of palindromes aroused our attention in our previous research. Whether these palindromes do have important influences on protein folding rates and what’s the mechanism? Very few related studies are focused on these problems. Objective: In this article, our motivation is to find out if palindromes have important influences on protein folding rates and what’s the mechanism. Method: In this article, the parameters of the palindromes were defined and calculated, the linear regression analysis between the values of each parameter and the experimental protein folding rates were done. Furthermore, to compare the results of different kinds of proteins, proteins were classified into the two-state proteins and the multi-state proteins. For the two kinds of proteins, the above linear regression analysis were performed respectively. Results : Protein folding rates were negatively correlated to the palindrome frequencies for all proteins. An extremely significant negative linear correlation appeared in the relationship between palindrome densities and protein folding rates. And the repeatedly used bases by different palindromes simultaneously have an important effect on the relationship between palindrome density and protein folding rate. Conclusion: The palindromes have important influences on protein folding rates, and the repeatedly used bases in different palindromes simultaneously play a key role in influencing the protein folding rates.

The Relationship Between The Perception of Elderly’s Health Status and Health Behaviors in Nakhon Nayok Province, Thailand

2019 ◽  
Vol 12 (1) ◽  
pp. 420-423
Author(s):  
Prapada Watcharanat ◽  
Prasong Tanpichai ◽  
Ravee Sajjasophon
Keyword(s):  
Regression Analysis ◽  
Health Status ◽  
Health Behaviors ◽  
Multiple Regression Analysis ◽  
Multiple Regression ◽  
Statistical Significance ◽  
The Elderly ◽  
Cross Sectional ◽  
Congenital Diseases ◽  
The Relationship

Purpose: This research aims to study the relationship between perception of elderly’s health and health behaviors in Nakhon Nayok province, Thailand Methods: This research was a cross-sectional study. The questionnaire was used to collect the data. This research was conducted in Nakhon Nayok province. The sample size was 270 which applied Taro Yamane's formula at a significant level 0.05. The descriptive statistics was implemented to describe the variables by presenting the frequency, percentage, mean and standard deviation. Furthermore, multiple regression analysis was applied to analyze the relationship between perception of elderly’s health and health behaviors. The statistical significance was considered to reject Hypothesis-null at < 0.05. Results: From a total of 270 people, more than 58.22% of the elderly perceived that they had moderate health conditions. Most elderly had congenital diseases (62.2%). The multiple regression analysis results showed that health status perception and health status perception when compared to their cohort related significantly to health behavior. Conclusion: The government should support the elderly on participation, trust, engagement, and cultural concern of the people in the community, which can contribute to promoting the physical, mental and social condition of the elderly.

scholarly journals Effect of Dietary Magnesium on Post Mortem Phosphocreatine Utilization in Skeletal Muscle of Swine: A Non-Invasive Study Using 31P-NMR Spectroscopy

1993 ◽  
Vol 34 (4) ◽  
pp. 397-404
Author(s):  
B. Moesgaard ◽  
I. Errebo Larsen ◽  
B. Quistorff ◽  
I. Therkelsen ◽  
V. Grøsfjeld Christensen ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Nmr Spectroscopy ◽  
31P Nmr ◽  
31P Nmr Spectroscopy ◽  
Post Mortem ◽  
Non Invasive ◽  
Dietary Magnesium

scholarly journals Investigating the Relationship between Public Satisfaction and Public Environmental Participation during Government Treatment of Urban Malodorous Black River in China

2021 ◽  
Vol 13 (6) ◽  
pp. 3584
Author(s):  
Shiwang Yu ◽  
Jianxia Bao ◽  
Wen Ding ◽  
Xue Chen ◽  
Xiaonan Tang ◽  
...  
Keyword(s):  
Public Participation ◽  
Public Perception ◽  
Action Plan ◽  
Linear Regression Analysis ◽  
Chinese Government ◽  
Whole Process ◽  
Residential Communities ◽  
Behavior Health ◽  
The Relationship ◽  
Environmental Participation

During China’s rapid economic development and urbanization, numerous cases of urban malodorous black river (MBR) have occurred. MBR refers to a polluted urban river that smells bad, is almost black in color, has no aquatic plants or animals, and that consequently causes many social and environmental problems. The Chinese government has sought public participation during the whole process of MBR treatment as part of a comprehensive action plan to improve residents’ satisfaction with their environment. To investigate the influencing factors of public participation and satisfaction, a questionnaire survey was conducted among residential communities close to an MBR. SPSS 22.0 was employed to conduct an analysis of the collected data, using factor analysis, correlation analysis, and linear regression analysis. The results indicate that there is a direct relationship between public satisfaction and the factors of government treatment, public perception and public participation behaviors, such as engagement behavior, supervision behavior, health influence, and compensation measures.

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