Platelet-Rich Fibrin in Regeneration of Intrabony Defects: A Randomized Controlled Trial

2017 ◽  
Vol 88 (11) ◽  
pp. 1192-1199 ◽  
Author(s):  
Gauresh Kumar Patel ◽  
Shivali S. Gaekwad ◽  
Sheela Kumar Gujjari ◽  
Veerendra Kumar S.C.
Keyword(s):  
Randomized Controlled Trial ◽  
Controlled Trial ◽  
Intrabony Defects ◽  
Platelet Rich Fibrin ◽  
Randomized Controlled

scholarly journals Effect of enamel matrix proteins on the treatment of intrabony defects: a split-mouth randomized controlled trial study

2007 ◽  
Vol 21 (3) ◽  
pp. 241-246 ◽  
Author(s):  
Daniela Chambrone ◽  
Ivan Munhoz Pasin ◽  
Marina Clemente Conde ◽  
Claudio Panutti ◽  
Silvia Carneiro ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Controlled Trial ◽  
Matrix Proteins ◽  
Treatment Modalities ◽  
Enamel Matrix ◽  
Intrabony Defects ◽  
Enamel Matrix Proteins ◽  
Pocket Depth ◽  
Randomized Controlled ◽  
Significant Difference

The objective of this split-mouth, double-blind, randomized controlled trial was to compare the clinical effect of treatment of 2- or 3-wall intrabony defects with open flap debridement (OFD) combined or not with enamel matrix proteins (EMP). Thirteen volunteers were selected with one pair of or more intrabony defects and probing pocket depth (PPD) > 5 mm. All individuals received instructions regarding oral hygiene and were submitted to scaling and root planing. Each participant received the two treatment modalities: test sites were treated with OFD and EMP, and control sites received only OFD. After 6 months, a significant reduction was observed in PPD for the EMP group (from 6.42 ± 1.08 mm to 2.67 ± 1.15 mm) and for the OFD group (from 6.08 ± 1.00 mm to 2.00 ± 0.95 mm) (p < 0.0001), but with no significant difference between groups (p = 0.13). A significant gain in relative attachment level (RAL) was observed in both groups (EMP: from 13.42 ± 1.88 mm to 10.75 ± 2.26 mm, p < 0.001; OFD: from 12.42 ± 1.98 mm to 10.58 ± 2.23 mm, p = 0.013), but with no significant difference between groups (p = 0.85). Gingival recession (GR) was higher in the EMP group (from 1.08 ± 1.50 mm to 2.33 ± 1.43 mm; p = 0.0009) than in the OFD group (from 0.66 ± 1.15 mm to 1.16 ± 1.33 mm; p = 0.16), but this difference was not significant (p = 0.06). In conclusion, the results showed that OFD combined with EMP was not able to improve treatment of intrabony defects compared to OFD alone.

Effect of Platelet-rich Fibrin on Healing of Apicomarginal Defects: A Randomized Controlled Trial

2015 ◽  
Vol 41 (7) ◽  
pp. 985-991 ◽  
Author(s):  
Meenu Dhiman ◽  
Suresh Kumar ◽  
Jigyasa Duhan ◽  
Pankaj Sangwan ◽  
Sanjay Tewari
Keyword(s):  
Randomized Controlled Trial ◽  
Controlled Trial ◽  
Platelet Rich Fibrin ◽  
Randomized Controlled
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