A Clinical and Histomorphometric Study of Calcium Sulfate Compared With Freeze-Dried Bone Allograft for Alveolar Ridge Preservation

2012 ◽  
Vol 83 (7) ◽  
pp. 847-855 ◽  
Author(s):  
Samira M. Toloue ◽  
Ioana Chesnoiu-Matei ◽  
Steven B. Blanchard
2014 ◽  
Vol 2014 ◽  
pp. 1-10 ◽  
Author(s):  
Andreas O. Parashis ◽  
Charalampos J. Kalaitzakis ◽  
Dimitris N. Tatakis ◽  
Konstantinos Tosios

Alveolar ridge preservation (ARP) has been shown to prevent postextraction bone loss. The aim of this report is to highlight the clinical, radiographic, and histological outcomes following use of a bilayer xenogeneic collagen matrix (XCM) in combination with freeze-dried bone allograft (FDBA) for ARP. Nine patients were treated after extraction of 18 teeth. Following minimal flap elevation and atraumatic extraction, sockets were filled with FDBA. The XCM was adapted to cover the defect and 2-3 mm of adjacent bone and flaps were repositioned. Healing was uneventful in all cases, the XCM remained in place, and any matrix exposure was devoid of further complications. Exposed matrix portions were slowly vascularized and replaced by mature keratinized tissue within 2-3 months. Radiographic and clinical assessment indicated adequate volume of bone for implant placement, with all planned implants placed in acceptable positions. When fixed partial dentures were placed, restorations fulfilled aesthetic demands without requiring further augmentation procedures. Histological and immunohistochemical analysis from 9 sites (4 patients) indicated normal mucosa with complete incorporation of the matrix and absence of inflammatory response. The XCM + FDBA combination resulted in minimal complications and desirable soft and hard tissue therapeutic outcomes, suggesting the feasibility of this approach for ARP.


2016 ◽  
Vol 87 (4) ◽  
pp. 416-425 ◽  
Author(s):  
Andreas O. Parashis ◽  
Charles E. Hawley ◽  
Paul C. Stark ◽  
Rumpa Ganguly ◽  
James B. Hanley ◽  
...  

2021 ◽  
Vol 2 (2) ◽  
pp. 18-22
Author(s):  
César Esquivel-Chirino ◽  
Vanessa Vargas-Romero ◽  
Gerardo Rodríguez-Torres ◽  
Verónica Villatoro-Ugalde ◽  
María Guadalupe Rivas-Fonseca ◽  
...  

Tooth extraction is a surgical procedure that is performed due to pulp and periapical pathology, periodontal disease, or teeth that are not deemed to be prosthetically or endodontically restorable. Following tooth extraction, bone resorption and vertical or horizontal defects occur. Traditionally, ridge preservation warrants the use of different agents such as autografts, allografts, xenografts, and mineral or ceramic materials. Autogenous dentin grafts are alternative to ridge preservation with osteoconductive, osteoinductive, and non-immunogenic properties to generate bone formation. The aim of the case report was to evaluate and compare clinical and histological outcomes using an autogenous dentin graft versus an allogeneic bone graft (DFDBA) as an alternative for ridge preservation.


2017 ◽  
Vol 43 (4) ◽  
pp. 267-273 ◽  
Author(s):  
Gi-Beom Cheon ◽  
Kyung Lhi Kang ◽  
Mi-Kyung Yoo ◽  
Jeoung-A Yu ◽  
Dong-Woon Lee

We evaluated the effectiveness of the open membrane technique using a high-density polytetrafluoroethylene (dPTFE) membrane with freeze-dried bone allografts in damaged sockets for alveolar ridge preservation (ARP). This retrospective study included 26 sites from 20 patients who had received ARP for the placement of dental implants. ARP was conducted using dPTFE membrane with allografts on the day of extraction without primary closure. When the membrane was removed after 4 weeks, the newly formed reddish tissue at the grafted site was checked (first outcome, clinical evaluation). Four months after membrane removal, a core biopsy was performed from the center of the grafted site before implant placement (second outcome, histomorphometric evaluation). Radiographic measurements of alveolar bone changes between implant prosthesis delivery and the 1-year follow-up were obtained (third outcome, radiographic evaluation). A total of 23 sites from 18 patients had no complications during the follow-up period. Three sites from two patients were excluded because of early membrane removal. Newly formed reddish tissue was found at 15 sites, and partially formed tissue was found at 8 sites. Although we were unable to harvest bone core from all sites, histomorphometric analysis in 11 patients indicated that the mean area of new bone was 28.48% ± 6.60%, that of the remaining graft particle was 27.68% ± 9.18%, and that of fibrous tissue was 43.84% ± 6.98%. The mean loss of marginal bone was 0.13 ± 0.06 mm at the mesial area and 0.15 ± 0.06 mm at the distal area, as assessed using radiographic evaluations. The results of this nonrandomized study suggest that this technique may be an appropriate procedure for ARP. Further studies with a control group and more subjectives can be designed based on this study.


Author(s):  
Hassan Azangookhiavi ◽  
Safoura Ghodsi ◽  
Fatemeh Jalil ◽  
Yalda Dadpour

Objectives: Bone remodeling after tooth extraction results in decreased ridge volume and complicates implant placement. Platelet-rich fibrin (PRF) is a rich source of autogenous cytokines and growth factors; it has been proven to effectively improve soft tissue healing and hard tissue regeneration. This study sought to compare the clinical application of freeze-dried bone allografts (FDBA) and PRF for alveolar ridge preservation after tooth extraction. Materials and Methods: This clinical trial was conducted on 32 patients presenting for the extraction of hopeless non-molar teeth. The teeth were extracted with minimal trauma, and the samples were randomly divided into two groups (n=16). Tooth sockets were filled with either FDBA or PRF (prepared using 10cc of the patient’s blood). Bone regeneration was assessed by evaluating changes in horizontal and vertical bone dimensions after 12 weeks (the time of implant placement) using an acrylic stent fabricated before tooth extraction and a periodontal probe. The results were compared by repeated-measures analysis of variance (ANOVA; P<0.05). Results: Ridge width showed a significant reduction compared to the baseline in both groups (P=0.001); ridge height changes were not significant (P>0.05). The evaluated groups did not show any significant difference in height/width changes (P>0.05). Conclusion: The results showed an acceptable efficacy for PRF without graft materials in alveolar ridge preservation. This material is cost-effective and could be easily prepared. PRF application in extraction sockets yielded similar results to FDBA.


2019 ◽  
Vol 2019 ◽  
pp. 1-7 ◽  
Author(s):  
Majdi A. Aladmawy ◽  
Zuhair S. Natto ◽  
Bjorn Steffensen ◽  
Paul Levi ◽  
Wai Cheung ◽  
...  

Aims. To assess the bone dimensional changes after extraction and alveolar ridge preservation (ARP) using primary coverage (closed flap technique, CFT) or healing by secondary intention (open flap technique, OFT). Materials and Methods. Ten patients (split mouth design) were planned for extraction and ARP. All sites received ARP with freeze-dried bone allograft (FDBA) and nonresorbable membrane after extraction. Clinical standardized measurements were used to assess the dimensional alterations of the alveolar ridge. Results. All patients completed the study, and a total of 20 sites were randomized to CFT or OFT group. Center height (mean difference of 8.1 mm, SD =1.9 CFT, and 7.5 mm, SD= 1.8 OFT) and buccal height (mean difference of 0.8 mm, SD =1.0 CFT, and 0.3 mm, SD= 1.1 OFT) were significantly different within the same group. However, there was no statistically significant difference between groups. In the OFT group, the keratinized tissue width was higher and the pain VAS scores at 24 hours were lower compared with the CFT (p = 0.004 and p = 0.006, respectively). Conclusions. Leaving the flap open did not have any effects on the dimensional changes of bone height or width. However, there was a wider band of keratinized tissue and less pain with the CFT compared with the OFT. The study protocol was registered at ClinicalTrials.gov, Identifier NCT03136913.


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