Histologic Evaluation of a Stem Cell–Based Sinus-Augmentation Procedure

2009 ◽  
Vol 80 (4) ◽  
pp. 679-686 ◽  
Author(s):  
Bradley S. McAllister ◽  
Kamran Haghighat ◽  
Aron Gonshor
Keyword(s):  
Stem Cell ◽  
Sinus Augmentation ◽  
Histologic Evaluation ◽  
Augmentation Procedure

Radiographic and histologic evaluation of platelet-rich plasma and bovine-derived xenograft combination in bilateral sinus augmentation procedure

Platelets ◽  
2012 ◽  
Vol 24 (4) ◽  
pp. 308-315 ◽  
Author(s):  
S. Yilmaz ◽  
E. Ozkan Karaca ◽  
S. Dirikan Ipci ◽  
G. Cakar ◽  
B.E. Kuru ◽  
...  
Keyword(s):  
Platelet Rich Plasma ◽  
Sinus Augmentation ◽  
Histologic Evaluation ◽  
Augmentation Procedure

Eight-Year Results of Site Retention of Anorganic Bovine Bone and Anorganic Bovine Matrix

2013 ◽  
Vol 39 (6) ◽  
pp. 727-732 ◽  
Author(s):  
Marco Degidi ◽  
Vittoria Perrotti ◽  
Adriano Piattelli ◽  
Giovanna Iezzi
Keyword(s):  
Bovine Bone ◽  
Cell Binding ◽  
Sinus Augmentation ◽  
Healing Period ◽  
A Cell ◽  
Etched Surface ◽  
Implant Loading ◽  
Titanium Dental Implants ◽  
Augmentation Procedure

The long-term fate of some biomaterials is still unknown, and the reports present in the literature are not conclusive as to whether these biomaterials are resorbed over time or not. Different reports can be found with regard to the resorption behavior of anorganic bovine bone (ABB). The aim of the present study was to provide a comparative histological and histomorphometrical evaluation, in the same patient, of 2 specimens retrieved from a sinus augmented with ABB and with anorganic bovine matrix added to a cell-binding peptide (PepGen P-15), respectively, after a healing period of 6 months and after 8 years of implant loading, to evaluate the resorption of both biomaterials. A unilateral sinus augmentation procedure with ABB (50%) and with PepGen P-15 (50%) was performed in a 54-year-old male patient. Two titanium dental implants with a sandblasted and acid-etched surface were inserted after 6 months. During this procedure, 2 tissue cores were retrieved from the sinus with a trephine, before implant insertion. After an additional 6 months, a fixed prosthetic restoration was fabricated. One of these implants, after a loading period of 8 years, fractured in the coronal portion and was removed. Both specimens, one retrieved after a 6-month healing period and the other after an 8-year loading period, were treated to obtain thin ground sections. In the 6-month specimen, the histomorphometry showed that the percentage of newly formed bone was 27.2% ± 3.6%, marrow spaces 35.6% ± 2.3%, residual ABB particles 25.1% ± 1.2%, and residual PepGen P-15 particles 12.1% ± 2.2%. In the 8-year specimen, the histomorphometry showed that the percentage of newly formed bone was 51.4% ± 4.8%, marrow spaces 40% ± 7.1%, residual ABB particles 6.2% ± 0.7%, and residual PepGen P-15 particles 2.4% ± 0.5%. Both biomaterials underwent significant resorption over the course of this study.

Radiographic and Histologic Evaluation of a Sinus Augmentation with Composite Bone Graft: A Clinical Case Report

2002 ◽  
Vol 73 (9) ◽  
pp. 1082-1088 ◽  
Author(s):  
Serge Armand ◽  
Axel Kirsch ◽  
Christophe Sergent ◽  
Philippe Kemoun ◽  
Gérard Brunel
Keyword(s):  
Case Report ◽  
Bone Graft ◽  
Clinical Case ◽  
Sinus Augmentation ◽  
Histologic Evaluation ◽  
Composite Bone

Volume Changes of Grafted Autogenous Bone in Sinus Augmentation Procedure

2011 ◽  
Vol 69 (6) ◽  
pp. 1633-1641 ◽  
Author(s):  
Carolina Sbordone ◽  
Ludovico Sbordone ◽  
Paolo Toti ◽  
Ranieri Martuscelli ◽  
Luigi Califano ◽  
...  
Keyword(s):  
Autogenous Bone ◽  
Volume Changes ◽  
Sinus Augmentation ◽  
Augmentation Procedure

Histologic Evaluation of a Provisional Implant Retrieved From Man 7 Months After Placement in a Sinus Augmented With Calcium Sulphate: A Case Report

2007 ◽  
Vol 33 (2) ◽  
pp. 89-95 ◽  
Author(s):  
Giovanna Iezzi ◽  
Elisabetta Fiera ◽  
Antonio Scarano ◽  
Gabriele Pecora ◽  
Adriano Piattelli
Keyword(s):  
Close Contact ◽  
Calcium Sulphate ◽  
Titanium Implants ◽  
Implant Surface ◽  
Sinus Augmentation ◽  
Bone Implant ◽  
Native Bone ◽  
Osteocyte Lacunae ◽  
Histologic Evaluation

Abstract Little is known about the in vivo healing processes at the interface of implants placed in different grafting materials. For optimal sinus augmentation, a bone graft substitute that can regenerate high-quality bone and enable the osseointegration of load-bearing titanium implants is needed in clinical practice. Calcium sulphate (CaS) is one of the oldest biomaterials used in medicine, but few studies have addressed its use as a sinus augmentation material in conjunction with simultaneous implant placement. The aim of the present study was to histologically evaluate an immediately loaded provisional implant retrieved 7 months after simultaneous placement in a human sinus grafted with CaS. During retrieval bone detached partially from one of the implants which precluded its use for histologic analysis. The second implant was completely surrounded by native and newly formed bone, and it underwent histologic evaluation. Lamellar bone, with small osteocyte lacunae, was present and in contact with the implant surface. No gaps, epithelial cells, or connective tissues were present at the bone–implant interface. No residual CaS was present. Bone–implant contact percentage was 55% ± 8%. Of this percentage, 40% was represented by native bone and 15% by newly formed bone. CaS showed complete resorption and new bone formation in the maxillary sinus; this bone was found to be in close contact with the implant surface after immediate loading.

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