scholarly journals Perspective: Late-Stage (T4) Translation Research and Implementation Science: The National Heart, Lung, and Blood Institute Strategic Vision

2017 ◽  
Vol 27 (4) ◽  
pp. 367 ◽  
Author(s):  
George A. Mensah ◽  
Cheryl Anne Boyce ◽  
LeShawndra N. Price ◽  
Helena O. Mishoe ◽  
Michael M. Engelgau

<p>In August 2016, the National Heart, Lung, and Blood Institute (NHLBI) released its Strategic Vision for charting a course for research over the next decade. This vision was the culmination of an unprecedented process that engaged diverse stakeholders from across the United States and around the globe. The process resulted in four mission-oriented goals and eight strategic objectives that provide an overall framework for advancing research in heart, lung, and blood diseases and sleep disorders. In this perspective, we address opportunities that NHLBI has identified to advance late-stage (T4) translation research, implementation science, health inequities research, global health research, and related research workforce development. Additionally, we highlight the importance of continued active engagement of the clinical and public health research community and the strategic, transdisciplinary, cross-sector partnerships necessary for advancing research priorities to maximize the population-level outcomes and health impact of scientific discoveries.</p><p><em>Ethn Dis. </em>2017;27(4):367-370; doi:10.18865/ed.27.4.367. </p>

Global Heart ◽  
2018 ◽  
Vol 13 (2) ◽  
pp. 65 ◽  
Author(s):  
Michael M. Engelgau ◽  
K.M. Venkat Narayan ◽  
Majid Ezzati ◽  
Luis A. Salicrup ◽  
Deshiree Belis ◽  
...  

2019 ◽  
Vol 29 (Suppl 1) ◽  
pp. 57-64 ◽  
Author(s):  
George A. Mensah ◽  
Catherine M. Stoney ◽  
Michelle M. Freemer ◽  
Sharon Smith ◽  
Michael M. Engelgau ◽  
...  

The National Heart, Lung, and Blood Institute (NHLBI) provides global leader­ship for a research, training, and education program to promote the prevention and treatment of heart, lung, and blood diseases and enhance the health of all individuals so that they can live longer and more fulfilling lives. Inherent in this mission is the com­mitment to advance health equity research as an avenue for enhancing the health of all individuals. Additionally, the four goals and eight research objectives of the NHLBI Strategic Vision directly support the com­mitment to health equity. In this article, we present selected examples of the NHLBI Strategic Vision implementation approaches for advancing health equity research in our mission areas of heart, lung, and blood diseases. Examples of diseases for which the burden of health inequities and our strategic vision implementation approaches are discussed include hypertension, heart failure, vascular dementia, asthma, and sickle cell disease. Examples are provided of new avenues of Institute-solicited re­search to stimulate and address compelling scientific questions and critical challenges to advance health equity. We also highlight the emerging fields of implementation sci­ence and predictive analytics as important opportunities to accelerate the translation of discovery science into health impact for all and to advance health equity.Ethn Dis.2019;29(Suppl1):57-64; doi:10.18865/ed.29.S1.57.


2018 ◽  
Vol 33 (5) ◽  
pp. 451-457 ◽  
Author(s):  
Ivy C. Mason ◽  
Mohamed Boubekri ◽  
Mariana G. Figueiro ◽  
Brant P. Hasler ◽  
Samer Hattar ◽  
...  

Despite the omnipresence of artificial and natural light exposure, there exists little guidance in the United States and elsewhere on light exposure in terms of timing, intensity, spectrum, and other light characteristics known to affect human health, performance, and well-being; in parallel, there is little information regarding the quantity and characteristics of light exposure that people receive. To address this, the National Center on Sleep Disorders Research, in the Division of Lung Diseases, National Heart, Lung, and Blood Institute, held a workshop in August 2016 on circadian health and light. Workshop participants discussed scientific research advances on the effects of light on human physiology, identified remaining knowledge gaps in these research areas, and articulated opportunities to use appropriate lighting to protect and improve circadian-dependent health. Based on this workshop, participants put forth the following strategic intent, objectives, and strategies to guide discovery, measurement, education, and implementation of the appropriate use of light to achieve, promote, and maintain circadian health in modern society.


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