scholarly journals Neighborhood Socioeconomic Status in Relation to All-cause, Cancer, and Cardiovascular Mortality in the Black Women’s Health Study

2016 ◽  
Vol 26 (2) ◽  
pp. 157 ◽  
Author(s):  
Traci N. Bethea ◽  
Julie R. Palmer ◽  
Lynn Rosenberg ◽  
Yvette C. Cozier

<p><strong>Background</strong>: Neighborhood socioeconomic status (SES) is associated with adverse health outcomes, but longitudinal data among Black Americans, who tend to live in more deprived neighborhoods, is lacking. <br />Objectives: We prospectively assessed the relation of neighborhood SES to mortality in the Black Women’s Health Study.</p><p><strong>Design</strong>: A prospective cohort of 59,000 Black women was followed from 1995-2011. Participant addresses were geocoded and US Census block group was identified. Neighborhood SES was measured by a score based on US Census block group data for six indicators of income, education and<br />wealth.</p><p><strong>Main outcome measures:</strong> Deaths were identified through the National Death Index. Cox proportional hazard models were used to estimate hazard ratios (HRs) and 95% CIs with control for covariates.</p><p><strong>Results</strong>: Based on 2,598 deaths during 1995-2011, lower neighborhood SES was associated with increased all-cause and cancer mortality irrespective of individual education: among those with 16 or more years of education, HRs for lowest relative to highest neighborhood SES quartile were 1.42 (95% CI 1.18-1.71) for all-cause and 1.54 (95% CI 1.14-2.07) for cancer mortality. Neighborhood SES was associated with cardiovascular mortality among lesseducated women.</p><p><strong>Conclusions</strong>: Lower neighborhood SES is associated with greater risk of mortality among Black women. The presence of the association even among women with high levels of education suggests that individual<br />SES may not overcome the unfavorable influence of neighborhood deprivation. <em>Ethn Dis</em>. 2016;26(2):157-164; doi:10.18865/<br />ed.26.2.157</p>

Blood ◽  
2009 ◽  
Vol 114 (22) ◽  
pp. 1954-1954
Author(s):  
James M. Foran ◽  
Laura A. McClure ◽  
Christina A. Clarke ◽  
Theresa H. M. Keegan

Abstract Abstract 1954 Poster Board I-977 Introduction: Despite advances in treatment and a well-characterized prognostic index, significant heterogeneity remains in DLBCL survival. Preliminary data suggest a potential survival disparity based on race/ethnicity or socioeconomic status (SES). To evaluate the impact of these and other variables on survival we performed an analysis in the ethnically diverse population-based California Cancer Registry (CCR). We utilized Neighborhood SES, an index of 7 census measures of education, income, occupation & cost of living, based on the residential census-block group at diagnosis. Each census-block group comprises ∼1500 residents. Neighborhood SES has been shown to be significantly associated with survival after Follicular Lymphoma (JCO 27:3044, 2009). Methods: All pts with DLBCL (ICD-O-3 codes 9680 & 9684) diagnosed from Jan 1988 to Dec 2007 and reported to CCR were included in the analysis, including n=16,892 diagnosed from 1988-2000, and n=11,916 from 2001-2007 (total study pop'n =28,808). HIV/AIDS pts were excluded, as were n=63 with Mediastinal LBCL & n=10 with primary effusion lymphoma. The mean age was 63 yrs, and the cohort was 53% male. Between time periods, there was a relative increase in Hispanic pts [15.4% (1988-2000) to 20.8% (2001-2007), p<0.001], and a 4% increase in advanced stage from 42% (1988-2000) to 46% (2001-2007) (p<0.001). Neighborhood SES was stratified into quintiles from lowest (SES-1) to highest (SES-5), the pt distribution was: SES-1, 14%; SES-2, 18%; SES-3, 21%; SES-4, 23%; and SES-5, 24%. To evaluate the impact of prognostic factors (particularly diagnosis period, SES, and race/ethnicity) on overall survival (OS) & disease-specific survival (DSS) we used Cox proportional hazards regression to calculate hazard ratios (HR) for death with 95% CI's. Multivariate regression models included variables significant at p<0.15 in univariate models or with a priori hypotheses for inclusion. Results are presented by stage at diagnosis [Localized/Regional (LocReg) vs. Advanced (ADV)]. Results: There was a significant improvement in OS in patients diagnosed after 2001 for both LocReg (HR 0.87, 95%CI 0.82-0.91, p<0.001) and ADV stage (HR 0.69, 95%CI 0.66-0.72, p<0.001), which correlates with the introduction of rituximab into therapy for DLBCL. As expected, age >60 years was associated with a significantly worse OS for LocReg (HR 3.06, 95%CI 2.90-3.24) and ADV stage (2.02, 95%CI 1.93-2.12). Females also had significantly better OS compared with males (Loc-Reg - HR 0.90, 95%CI 0.86-0.94; ADV - HR 0.89, 95%CI 0.85-0.93). There was no significant impact of race/ethnicity on survival with the exception of non-Hispanic Asian/Pacific Islanders (NH A/PI) with ADV stage, for whom OS was significantly inferior compared with whites (HR 1.18, 95%CI 1.09-1.27, p<0.001). Compared with the highest quintile (SES-5), there was a significant effect of lower neighborhood SES on OS and DSS (see Table). Conclusion: There has been a significant improvement in survival after DLBCL since 2001, but patients in the lowest SES-1 quintile have a 34% higher risk of death from any cause and 20% higher risk for death from lymphoma than those in the highest SES-5. In this model, race/ethnicity did not have a significant impact on survival with the exception of NH A/PI with ADV stage. Studies to understand and address these socioeconomic disparities are urgently required in order to extend the improvements in DLBCL survival more effectively. Disclosures: Foran: Genentech: Honoraria, Research Funding.


2012 ◽  
Vol 9 (8) ◽  
pp. 1074-1079 ◽  
Author(s):  
Patricia F. Coogan ◽  
Laura F. White ◽  
Stephen R. Evans ◽  
Julie R. Palmer ◽  
Lynn Rosenberg

Background:Influences on TV viewing time, which is associated with adverse health outcomes such as obesity and diabetes, need clarification. We assessed the relation of neighborhood socioeconomic status (SES) and walkability with TV viewing time in the Black Women’s Health Study, a prospective study of African American women.Methods:We created neighborhood SES and walkability scores using data from the U.S. census and other sources. We estimated odds ratios for TV viewing 5+ hours/day compared with 0–1 hours/day for quintiles of neighborhood SES and walkability scores.Results:Neighborhood SES was inversely associated with TV viewing time. The odds ratio for watching 5+ hours/day in the highest compared with the lowest quintile of neighborhood SES was 0.66 (95% CI 0.54–0.81). Neighborhood walkability was not associated with TV viewing time.Conclusions:Neighborhood SES should be considered in devising strategies to combat the high levels of sedentariness prevalent in African American women.


Obesity ◽  
2010 ◽  
Vol 18 (10) ◽  
pp. 2064-2065 ◽  
Author(s):  
Patricia F. Coogan ◽  
Yvette C. Cozier ◽  
Supriya Krishnan ◽  
Lauren A. Wise ◽  
Lucile L. Adams-Campbell ◽  
...  

2016 ◽  
Vol 26 (1) ◽  
pp. 17
Author(s):  
Tingjian Yan ◽  
Li-Jung Liang ◽  
Stefanie Vassar ◽  
Monica Cheung Katz ◽  
Jose J. Escarce ◽  
...  

<p><strong>Objective:</strong> To examine variation by race and gender in the association between neighborhood socioeconomic status and walking among community-dwelling older adults.</p><p><strong>Design:</strong> Cross-sectional.</p><p><strong>Setting:</strong> Cardiovascular Health Study, a longitudinal population-based cohort.</p><p><strong>Participants:</strong> 4,849 adults aged &gt;65 years.</p><p><strong>Measurements:</strong> Participants reported number of city blocks walked in the prior week. Neighborhood socioeconomic status (NSES) measured at the level of the census tract. Negative binominal regression models were constructed to test the association between NSES and blocks walked. In the fully adjusted models, we included two-way and three-way interaction terms among race, gender, and NSES. </p><p><strong>Results</strong>: In adjusted analyses, among White residents in the lowest NSES quartile (most disadvantaged), men walked 64% more than women (<em></em>P&lt;.001), while in the highest NSES (most advantaged), men walked 43% more than women (<em></em>P&lt;.001).  Among African American residents in the lowest NSES quartile, men walked 196% more blocks than women (<em></em>P&lt;.001), while in the highest NSES, men walked 43% more blocks than women, but this did not reach statistical significance (<em></em>P=.06). </p><p><strong>Conclusions:</strong> Female gender is more strongly associated with walking for African Americans than for Whites in low SES neighborhoods but had a similar association with walking for both African Americans and Whites in high SES neighborhoods. <em>Ethn Dis. </em>2016;26(1):17-26; doi:10.18665/ed.26.1.17</p>


2020 ◽  
Vol 1 (1) ◽  
Author(s):  
Bruce Ramphal ◽  
Mariah DeSerisy ◽  
David Pagliaccio ◽  
Elizabeth Raffanello ◽  
Virginia Rauh ◽  
...  

Abstract Although severe early life stress has been shown to accelerate the development of frontolimbic resting-state functional connectivity (RSFC), less is known about the effects of socioeconomic disadvantage, a prolonged and multifaceted stressor. In a cross-sectional study of 127 participants aged 5–25, we examined whether lower neighborhood socioeconomic status (SES; measured by Area Deprivation Index and neighborhood poverty and educational attainment) was associated with prematurely reduced amygdala-ventromedial prefrontal cortex (vmPFC) RSFC. We further tested whether neighborhood SES was more predictive than household SES and whether SES effects on connectivity were associated with anxiety symptoms. We found reduced basolateral amygdala-vmPFC RSFC at earlier ages in participants from more disadvantaged neighborhoods; this effect was unique to neighborhood SES and absent for household SES. Furthermore, this reduced connectivity in more disadvantaged youth and increased connectivity in more advantaged youth were associated with less anxiety; children who deviated from the connectivity pattern associated with their neighborhood SES had more anxiety. These results demonstrate that neighborhood socioeconomic disadvantage is associated with accelerated maturation of amygdala-vmPFC RSFC and suggest that the pathophysiology of pediatric anxiety depends on a child’s neighborhood socioeconomic characteristics. Our findings also underscore the importance of examining SES effects in studies of brain development.


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