scholarly journals In Cats Infected With Feline Herpesvirus Type-1 (FHV-1) Does Treatment With Famciclovir Result in a Reduction of Respiratory and Ocular Clinical Signs?

2017 ◽  
Vol 2 (3) ◽  
Author(s):  
Jacqueline Cole

Clinical bottom line Based on the current available evidence, famciclovir may have a positive effect on reducing respiratory and ocular clinical signs of feline herpesvirus type-1 (FHV-1) disease, however further research is needed before famciclovir can be routinely recommended as part of a treatment protocol for this disease.

1994 ◽  
Vol 28 (4) ◽  
pp. 320-329 ◽  
Author(s):  
Mary A. Hickman ◽  
Gerhard H. Reubel ◽  
Diane E. Hoffman ◽  
James G. Morris ◽  
Quinton R. Rogers ◽  
...  

This study describes the clinical course of an inadvertent feline herpesvirus, type 1 (FHV-1) outbreak in 2 specific pathogen-free (SPF) research and breeding colonies housing 690 cats and assesses a programme that was designed to eradicate the virus from the colonies. The clinical signs observed in these cats were milder, with more eye involvement than those previously described for FHV-1 infection and did not include abortion. FHV-1 eradication was based on the detection and elimination of both active and latent viral carriers. Carrier cats were detected by virus isolation from oral swabs before and after corticosteroid-induced reactivation of FHV-1 excretion. Four per cent of recovered cats were actively shedding virus prior to corticosteroid treatment; 21 % of the virus negative cats shed virus after one corticosteroid injection, and 12% of remaining culture negative cats tested positive upon a second corticosteroid treatment 6 weeks later. The colony remained virus free for 8 months after all detectable virus carriers were culled and there was no seroconversion among new kittens. A second epizootic of FHV-1 then occurred among susceptible animals. At this time, all breeding cats that had tested negative after 2 injections of corticosteroids were treated a third time; 23% of them now tested positive for FHV-1. This study demonstrates that corticosteroid treatment can be useful in improving the rate of detection, essential as a basis for decreasing the incidence of enzootic disease, but it is unlikely to detect all possible FHV-1 carriers in large populations of cats.


1991 ◽  
Vol 28 (4) ◽  
pp. 338-340 ◽  
Author(s):  
J. W. Kramer ◽  
J. F. Evermann ◽  
C. W. Leathers ◽  
A. J. McKeirnan ◽  
L. Rashti

1992 ◽  
Vol 126 (1-4) ◽  
pp. 283-292 ◽  
Author(s):  
T. Horimoto ◽  
J. A. Limcumpao ◽  
X. Xuan ◽  
M. Ono ◽  
K. Maeda ◽  
...  

1986 ◽  
Vol 41 (3) ◽  
pp. 323-330 ◽  
Author(s):  
F.M. COCKER ◽  
T.J. NEWBY ◽  
R.M. GASKELL ◽  
P.A. EVANS ◽  
C.J. GASKELL ◽  
...  

1991 ◽  
Vol 53 (3) ◽  
pp. 423-432 ◽  
Author(s):  
Joselito A. LIMCUMPAO ◽  
Taisuke HORIMOTO ◽  
Xuenan XUAN ◽  
Yukinobu TOHYA ◽  
Masayuki AZETAKA ◽  
...  

1995 ◽  
Vol 39 (1) ◽  
pp. 55-61 ◽  
Author(s):  
Ken Maeda ◽  
Kensuke Hirasawa ◽  
Yasushi Kawaguchi ◽  
Mitsuru Ono ◽  
Takeshi Mori ◽  
...  

2002 ◽  
Vol 88 (2) ◽  
pp. 144-149 ◽  
Author(s):  
Masayuki Mishima ◽  
Xuenan Xuan ◽  
Naoaki Yokoyama ◽  
Ikuo Igarashi ◽  
Kozo Fujisaki ◽  
...  

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