scholarly journals Observation on Clinical Efficacy and Safety of Amiodarone in the Treatment of Malignant Arrhythmia after Acute Myocardial Infarction (AMI)

2018 ◽  
Vol 6 (3) ◽  
Author(s):  
Jiazhong Lu
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Heart Rate ◽  
Mean Arterial Pressure ◽  
Arterial Pressure ◽  
Clinical Efficacy ◽  
Clinical Treatment ◽  
Efficacy And Safety ◽  
Curative Effect ◽  
Malignant Arrhythmia

<p>To investigate the clinical efficacy and safety of ethylamine iodine in the treatment of malignant arrhythmia after acute myocardial infarction. Method: 35 patients with malignant arrhythmia after acute myocardial infarction were enrolled in our hospital from May 2013 to August 2014. The patients were treated with ethidium iodide load of 75-150 mg/times. The patients were treated with intravenous infusion of 0.5-1.0 mg/min micro pump at 15-20 min. The clinical curative effect and the heart rate were analyzed at 15 min, 1, 2 and 24 h after treatment respectively, mean arterial pressure changes and adverse reactions and so on. Results: The total effective rate was 91.43% in the clinical treatment. The heart rate, mean arterial pressure and the difference before treatment were significant (P &lt;0.05) at 15 min, 1, 2, and 24 h after treatment and the drug dose was adjusted in 3 patients after bradycardia after return to the normal range. Conclusion: Ethylamine iodine can be used in the clinical treatment of acute myocardial infarction and malignant arrhythmia. It can achieve significant clinical curative effect, high safety and mild adverse reaction. It is worthy to be popularized and applied.</p>

scholarly journals Clinical efficacy and safety of Shuxuetong injection for acute myocardial infarction

Medicine ◽  
2021 ◽  
Vol 100 (7) ◽  
pp. e24773
Author(s):  
Feng Yu ◽  
Mengxue Xin ◽  
Na Huang ◽  
Taotao Zhang ◽  
JianHui Lu ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Clinical Efficacy ◽  
Efficacy And Safety

scholarly journals Comparison between esmolol and verapamil in attenuation of cardiovascular stress response to laryngoscopy and endotracheal intubation in elective surgery

2021 ◽  
Vol 12 (7) ◽  
pp. 64-68
Author(s):  
Nitisha Chakraborty ◽  
Sankar Roy ◽  
Debajyoti Sur ◽  
Arunava Biswas ◽  
Dipasri Bhattacharya ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Body Weight ◽  
Mean Arterial Pressure ◽  
Arterial Pressure ◽  
Diastolic Blood Pressure ◽  
Endotracheal Intubation ◽  
Efficacy And Safety ◽  
Cardiovascular Stress ◽  
The Mean

Background: Cardiovascular stress due to reflex sympathetic over activity is a great concern during laryngoscopy and endotracheal intubation. Aims and Objectives: To compare the efficacy and safety of esmolol and verapamil for attenuation of hemodynamic effects (heart rate, systolic blood pressure, diastolic blood pressure and mean arterial pressure) due to laryngoscopy and endotracheal intubation in elective surgical cases. Materials and Methods: A prospective, randomized, double blinded, controlled study was conducted on 60 patients divided equally into 30 each receiving esmolol (2 mg/kg body weight) and verapamil (0.1 mg/kg body weight) respectively. Heart rate, systolic and diastolic blood pressure and mean arterial pressure were recordedat pre-operative stage, after administration of the study drugs, immediately after intubation and at 1 ,3 ,5 minutes after intubation. Data collected were statistically analyzed. Results: The mean systolic blood pressure was lower in the esmolol group at all times of estimation compared with the verapamil group and the difference was at the time of intubation (p value <0.001).The mean diastolic blood pressure was lower in the esmolol group at all times of estimation compared to the verapamil group which was not statistically significant at any time of estimation. The mean arterial pressure was significantly lower at the time of immediately after intubation (p<0.001) in esmolol as compared to verapamil group. Adverse effects in both the study groups were insignificant. Conclusion: Esmololand Verapamil can effectively attenuate the cardiovascular stress to laryngoscopy and endotracheal intubation with the former appears to be a better alternative from efficacy and safety perspectives.

Carvedilol Versus Propranolol in the Prevention of Variceal Rebleeding in Hepatic Schistosomiasis: Efficacy and Safety

2021 ◽  
Author(s):  
Chantelli Iamblaudiot Razafindrazoto ◽  
Lova Dany Ella Razafindrabekoto ◽  
Domoina Harivonjy Hasina Laingonirina ◽  
Raveloson Raveloson ◽  
Anjaramalala Sitraka Rasolonjatovo ◽  
...  
Keyword(s):  
Heart Rate ◽  
Portal Hypertension ◽  
Mean Arterial Pressure ◽  
Arterial Pressure ◽  
Variceal Bleeding ◽  
Efficacy And Safety ◽  
Effective Prevention ◽  
Significant Difference ◽  
Propranolol Group ◽  
The Mean

Abstract Background: The betablockers combined with endoscopic variceal band ligation (EVL) is the most effective prevention of variceal rebleeding. The aim of this study is to evaluate the efficacy and safety of carvedilol compared to propranolol as secondary prevention of variceal bleeding in hepatic schistosomiasis. Methods: All patients with portal hypertension due to schistosomiasis presenting for EVL with at least one episode of variceal bleeding were included and randomized into propranolol + EVL and Carvedilol + EVL groups. Results: Sixty-one patients were selected and randomized into the propranolol group (n=30) and carvedilol group (n=31). We noted less recurrence of bleeding in the carvedilol group (n=1) than in the propranolol group (n=3) (3.33% vs 10%; p=0.30). Bleeding recurrence occurred after 30 days in the carvedilol group and after 5, 45 and 90 days in the propranolol group. At 4 months, a significant reduction in mean arterial pressure (-4.13 mmHg; 95%CI: -6.27 and -1.99; p <0.05) and heart rate (-12.13 mmHg; 95%CI: -13.92 and -10.35; p<0.05) was found in the carvedilol group. There was no significant difference between the two groups on the mean difference in mean arterial pressure. A patient in the carvedilol group presented breathing difficulty. No adverse effects have been demonstrated in the propranolol group. Conclusion: Carvedilol is as effective as propranolol in the prevention of variceal rebleeding in hepatic schistosomiasis.

scholarly journals Prognosis of acute myocardial infarction outcomes using evaluation of cardiac power (product of cardiac output and mean arterial pressure)

Critical Care ◽  
2009 ◽  
Vol 13 (Suppl 1) ◽  
pp. P161
Author(s):  
A Macas ◽  
A Krisciukaitis ◽  
V Saferis ◽  
G Baksyte ◽  
A Mundinaite ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Cardiac Output ◽  
Mean Arterial Pressure ◽  
Arterial Pressure ◽  
Cardiac Power ◽  
Power Product
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